Gene Information

Name : AFE_3161 (AFE_3161)
Accession : YP_002427523.1
Strain : Acidithiobacillus ferrooxidans ATCC 23270
Genome accession: NC_011761
Putative virulence/resistance : Resistance
Product : D-isomer specific 2-hydroxyacid dehydrogenase family protein
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1052
EC number : -
Position : 2842362 - 2843357 bp
Length : 996 bp
Strand : -
Note : identified by match to protein family HMM PF00389; match to protein family HMM PF02826

DNA sequence :
ATGCGTTGTCTGGTGACCAGTGCTCGCCCTTACGATGAACAATTCCTCAGCGCCGCCAACCATGGACGCCACGAATTGGT
ATTTGTTGAAACCGCACTGAGCGCGGATACGGCTTTTATTGCCCAGGGATACCCTGCCATTTGCCCCTTCGTGGATGACA
CGCTGGACGCAAAAACACTGGAAACCATAGCGCGCTTGGGGACTAAACTACTGGTCTTGCGCAGCACCGGGTTCAATCAT
GTGGACATGCCTGCGGCCGAGAAGTACGGCATCACCGTCATGCGGGTACGCGATTATTCCCCTTATGCGGTGGCTGAATA
TGCCGTCGGCCTGATGTTGACCCTGAACCGACACCTGCATAAAGCCTATAACCGGGTGCGTGACGGTAATTTTCTCCTCG
ACGGCTTGCTGGGTTTTGACATGCATGGCAAAACCGTAGGCATTATCGGCACTGGAAAAATTGGCCAGGCACTCGCCCGG
ATTCTGCATGGTATGGGCTGCCACTTGTTGGGCTACGACACAGTCGCCAATCCCGCGTGCCTGGAACTCGGCGTTGCATA
TGTACCGCTGGAAGAATTGCTCGTCAAAAGCCAAATCGTCAGCCTCCATGTGCCGCTGCTCCCGGAAACCCGGCATCTGA
TGAATGCGGAACGGTTCGCCTTGATGCCGGACGGTGCCATGCTGATCAATACCAGCCGTGGTCCGCTCATCGACACCACG
GCACTCATTGCGGCACTGAAAAGCCGCCATCTGGGTGCTGTGGGTCTGGATGTCTATGAAGAAGAGGCAGAATTATATTT
TAAGGATCATTGCGATGACATTATCTGCGATGACAGCTTCGAACGGCTGCTCACTTTTCCCAATGTCATCATCACGGGCC
ATCAGGCCTTTTTTACCAGTGAGGCACTGACCACCATTGCCAGGACCACGATCCAGAACCTGGATGACTACAGCGATGGA
AAGGATAATCCCAATTGCGTTCGCAGCAAGGGATGA

Protein sequence :
MRCLVTSARPYDEQFLSAANHGRHELVFVETALSADTAFIAQGYPAICPFVDDTLDAKTLETIARLGTKLLVLRSTGFNH
VDMPAAEKYGITVMRVRDYSPYAVAEYAVGLMLTLNRHLHKAYNRVRDGNFLLDGLLGFDMHGKTVGIIGTGKIGQALAR
ILHGMGCHLLGYDTVANPACLELGVAYVPLEELLVKSQIVSLHVPLLPETRHLMNAERFALMPDGAMLINTSRGPLIDTT
ALIAALKSRHLGAVGLDVYEEEAELYFKDHCDDIICDDSFERLLTFPNVIITGHQAFFTSEALTTIARTTIQNLDDYSDG
KDNPNCVRSKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
EF2295 NP_815952.1 D-specific alpha-keto acid dehydrogenase Not tested Not named Protein 3e-33 42
vanHB YP_008394258.1 VanH protein, D-specific alpha-keto acid dehydrogenase Not tested Not named Protein 8e-34 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
AFE_3161 YP_002427523.1 D-isomer specific 2-hydroxyacid dehydrogenase family protein U35369.1.gene5.p01 Protein 2e-33 42
AFE_3161 YP_002427523.1 D-isomer specific 2-hydroxyacid dehydrogenase family protein AF310956.2.orf4.gene Protein 4e-34 42
AFE_3161 YP_002427523.1 D-isomer specific 2-hydroxyacid dehydrogenase family protein NC_005054.2598279.p0 Protein 2e-30 42
AFE_3161 YP_002427523.1 D-isomer specific 2-hydroxyacid dehydrogenase family protein NC_014475.1.orf2.gen Protein 2e-30 42