Gene Information

Name : AFE_2955 (AFE_2955)
Accession : YP_002427322.1
Strain : Acidithiobacillus ferrooxidans ATCC 23270
Genome accession: NC_011761
Putative virulence/resistance : Virulence
Product : sigma-54 dependent DNA-binding response regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG2204
EC number : -
Position : 2639809 - 2641182 bp
Length : 1374 bp
Strand : -
Note : identified by match to protein family HMM PF00072; match to protein family HMM PF00158

DNA sequence :
ATGGAAAAAGGCAGAATCTTACTCGTGGATGATGACGCCGATCTCCTGCGTCTGTTGTCCCTGCGCATGAAGGCGGCCGG
CTATGTGGTCAGCACCGCGGCCAGCGGCAGCGAAGCGTTGTCGGTACTGGCGATGGAGCACCCGTCCCTGGTCATCACCG
ATCTCAAGATGGATGAGATGGACGGTATGGCGCTGCTGGACGCCATTCGCCGCGACTACCCGACGTTGCCCGTCATCATC
CTTACCGCCCACGGTTCCATCCCCGATGCCCTGCTGGCCGCTGACCAGGGTGTCTTTGCCTTCCTCACCAAGCCTTTTGA
TGGCAAGGATCTGATGGCGCAGGTGGAGCGTGCCTTCAACCTGACGGCGGCGGTTCCCCCTTCTTCGGGCAAGAAGGGCC
GGGACTCCAGTTGGGACCGGATCCTGACCCGCAGCCCCAAAATGCAGACGGTGCTGGATCAGGCGCGTCTGGTGGCGGCA
TCCGATGCCAGCGTCTTCATTCATGGCGCCAGTGGTACCGGTAAGGAACTGCTGGCCCAGGCCATCCATCAGGCGAGTCC
GCGCCATGGCCACGCCTTTATTGCCGTCAACTGCGCGGCCTTTCCCGAGCAACTGCTGGAGTCGGAACTCTTCGGGCACA
AAAAGGGCGCCTTCACCGGAGCGGCCAGCAGTCATCAGGGCCTGTTCCAGGCGGCGGAGGGCGGCACGCTTTTTCTGGAC
GAAATTGGCGATATGCCTCTCCCGTTACAGGTCAAACTGCTGCGCGCCCTGCAGGAACGGATGATTCGTCCGGTCGGCGC
CACCGAGAGCATCGCCGTCGACGTGCGGATCATCTCCGCCAGTCACCGGGATTTGGAGCAGGAGATGGCTGCCCGGCGTT
TCCGGGATGATCTCTACTATCGCCTTTGCGTGGTGACCCTGGAACTTCCCGCCCTGGCGGAGCGCCCGGAGGATATCCCG
CTGCTGGCCGAGTTTTTCCTGCGAGATGCGGCGGCCAAGAATCGCAAGGACGTTCGCGGGATCGCGCCGGAAGCCATGGA
ACTGCTCGTATCGGCGCCCTGGCCGGGCAATGTCCGGCAGCTCGCCAACGTCATCGAACAGGCGGTGGTGCTGTCCACTA
CCCCGCGAATCGGGGCGCCCCTCATCCGTCATGCCTTGCGTGACCGGGAAGGGGAGGTCATGCCTCTGGCCGATGCCAAG
GGCCGTTTCGAGATGAATTATCTGATCCAGATCATGCGCATGACCCGCGGCAACGTGAGTCAGGCCGCACAACTCGCACA
GCGCAACCGCACCGAGTTTTATCGCCTCCTGCACCGCTACCACCTCGATCCCGCCGCCTTCAAGGAAGCCGGTGGTGAAG
CGGAGGAGGAGTAG

Protein sequence :
MEKGRILLVDDDADLLRLLSLRMKAAGYVVSTAASGSEALSVLAMEHPSLVITDLKMDEMDGMALLDAIRRDYPTLPVII
LTAHGSIPDALLAADQGVFAFLTKPFDGKDLMAQVERAFNLTAAVPPSSGKKGRDSSWDRILTRSPKMQTVLDQARLVAA
SDASVFIHGASGTGKELLAQAIHQASPRHGHAFIAVNCAAFPEQLLESELFGHKKGAFTGAASSHQGLFQAAEGGTLFLD
EIGDMPLPLQVKLLRALQERMIRPVGATESIAVDVRIISASHRDLEQEMAARRFRDDLYYRLCVVTLELPALAERPEDIP
LLAEFFLRDAAAKNRKDVRGIAPEAMELLVSAPWPGNVRQLANVIEQAVVLSTTPRIGAPLIRHALRDREGEVMPLADAK
GRFEMNYLIQIMRMTRGNVSQAAQLAQRNRTEFYRLLHRYHLDPAAFKEAGGEAEEE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00300 YP_008207765.1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Not tested AbaR25 Protein 1e-58 41
BJAB0868_00304 YP_008211630.1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Not tested AbaR26 Protein 1e-58 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
AFE_2955 YP_002427322.1 sigma-54 dependent DNA-binding response regulator BAC0467 Protein 3e-78 50
AFE_2955 YP_002427322.1 sigma-54 dependent DNA-binding response regulator BAC0089 Protein 6e-82 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
AFE_2955 YP_002427322.1 sigma-54 dependent DNA-binding response regulator VFG1249 Protein 1e-68 48
AFE_2955 YP_002427322.1 sigma-54 dependent DNA-binding response regulator VFG1214 Protein 7e-66 45
AFE_2955 YP_002427322.1 sigma-54 dependent DNA-binding response regulator VFG0116 Protein 9e-56 42