Gene Information

Name : smpB (AFE_0277)
Accession : YP_002424784.1
Strain : Acidithiobacillus ferrooxidans ATCC 23270
Genome accession: NC_011761
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 249876 - 250337 bp
Length : 462 bp
Strand : -
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGAGCAGCACCATCGCCCTCAATCGCGAGGCGAAACATGAATACTTTATTGAAGAGCGCTTTGAAGCCGGCATGGTCTT
ACAGGGCTGGGAGGTGAAGTCGCTGCGTGCCAACCGGCTCACTCTCAAAGACAGTTATATCATCGTCAAAAATGCGGAAC
TCTGGTTGCTGGGCGCGCACATCAGTCCACTGCCTACCGCCAGCACCCATATAAACCCTGACCCGACACGCACCCGCAAG
CTGCTGATGCACAGGGAACAGATCAATCGCATGATCGGTAGTGTCGAGCGCAAGGGCTTTACGATCGTGCCCCTGGCCAT
GTACTGGAAGCAAGGCCGTGCCAAAGTGGAAATCGCACTGGTGAAGGGCAAACAGGAGCACGACAAACGTGCCACGGTCA
AAGACCGGGAATGGCAGCGGGACAAGGCGCGCATCATGAAGGGCGGGGCGCGGGATGTCTGA

Protein sequence :
MSSTIALNREAKHEYFIEERFEAGMVLQGWEVKSLRANRLTLKDSYIIVKNAELWLLGAHISPLPTASTHINPDPTRTRK
LLMHREQINRMIGSVERKGFTIVPLAMYWKQGRAKVEIALVKGKQEHDKRATVKDREWQRDKARIMKGGARDV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 4e-38 50
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 3e-26 45
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 7e-24 41