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Name : merA (AFE_2481) Accession : YP_002426863.1 Strain : Acidithiobacillus ferrooxidans ATCC 23270 Genome accession: NC_011761 Putative virulence/resistance : Resistance Product : mercuric reductase Function : - COG functional category : C : Energy production and conversion COG ID : COG1249 EC number : 1.16.1.1 Position : 2212525 - 2214168 bp Length : 1644 bp Strand : + Note : identified by similarity to SP:P17239; match to protein family HMM PF00070; match to protein family HMM PF00403; match to protein family HMM PF01266; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIG DNA sequence : ATGACCGAGAACGCGCCCACCGAACTCGCTATCACTGGCATGACCTGCGACGGTTGCGCCGCGCATGTGCGCAAAGCACT CGAAGGCGTGCCCGGCGTACGCGAGGCGCAGGTGTCCTACCCGGATGCCACGGCCCGGGTCGTGCTGGAGGGCGAGGTGC CGATGCAGCGGCTAATCAAGGCGGTGGTTGCAAGTGGCTATGGTGTGCATCCACGGAGCGACGGTGCCTCCTCCACAAAC GATGGACAGGAGCTACACATCGCTGTGATCGGCAGCGGCGGAGCGGCGATGGCGTGCGCATTGAAGGCTGTCGAGCGGGG CGCGCGCGTGACGCTGATCGAACGCAGCACCATCGGCGGCACCTGCGTGAACATCGGTTGCGTGCCGTCCAAGATCATGA TCCGCGCCGCCCATATCGCCCACCTGCGCCGGGAAAGCCCATTCGATGGCGGCATCCAGGCGGTCGCGCCGACCATCCAG CGCACAGCGCTGCTGGTCCAACAGCAGGCCCGTGTCGATGAACTGCGTCACGCCAAGTACGAAGGCATCCTGGACGGCAA CCCGGCCATCACCGTTCTGCGCGGTGAAGCGCGTTTCAAGGACAGCCGGAGTGTTGTCGTCCATTTGAACGATGGTGGCG AGCGCGTCGTAATGTTCGACCGCTGCCTGGTTGCCACGGGCGCCAGTCCGGCCGTGCCGCCGATTCCCGGCTTGAAAGAC ACTCCTTATTGGACCTCCACCGAAGCGCTGGTCAGCGAATCGATCCCCGAGCGTCTGGCCGTGATCGGCTCGTCGGTGGT GGCGCTGGAACTGGCGCAAGCCTTCGCCCGGCTCGGCAGCCATGTGACGATCCTGGCGCGCGGCACCTTGTTCCTCCGGG AAGACCCGGCCATCGGTGAGGCCATCACGGCGGCGTTTCGCGCCGAAGGCATCGAGGTGCTGGAGCACACCCAGGCCAGC CAGGTCGCTTATGCGGATGGCGAATTTGTGCTAGCCACCGGGCACGGCGAACTGCGCGCCGATAAGCTGCTGGTCGCCAC TGGTCGCGCACCGAACACACGCCGCCTGAATCTGGAAGCGGCGGGCGTGGCCATCAATGCGCAAGGGGCCATCGTCATCG ACCAGGGTATGCGCACGAACAGCCCGAACATTTACGCCGCTGGCGACTGCACCGACCAGCCGCAATTCGTCTACGTGGCG GCAGCGGCCGGCACCCGTGCGGCCATCAACATGATGGGCGGTAGTGCAGCCCTGGACTTGACGGCGATGCCAGCCGTGGT GTTCACCGATCCGCAAGTGGCGACTGTGGGTTACAGCGGCGCGGAAGCGCATCGCGACGGCATCGAAACCGACAGCCGCA CGCTGACGCTCGACAACGTGCCGCGGGCGCTCGCCAATTTCAATACACGCGGCTTCATCAAGCTGGTAGCCGAAGTGGGC AGTGGTCGCCTAATCGGCGTGCAGGTGGTCGCCCCGGAAGCGGGCGAGCTGATCCAGACTGCCGCGCTGGCGATTCGTAA CCGGATGACGGTACAGGAACTGGCTGACCAGTTGTTTCCCTACCTGACGATGGTCGAAGGGCTGAAGCTTGCTGCCCAGA CCTTCACCAGGGATGTGAAGCAGTTGTCCTGCTGTGCGGGTTGA Protein sequence : MTENAPTELAITGMTCDGCAAHVRKALEGVPGVREAQVSYPDATARVVLEGEVPMQRLIKAVVASGYGVHPRSDGASSTN DGQELHIAVIGSGGAAMACALKAVERGARVTLIERSTIGGTCVNIGCVPSKIMIRAAHIAHLRRESPFDGGIQAVAPTIQ RTALLVQQQARVDELRHAKYEGILDGNPAITVLRGEARFKDSRSVVVHLNDGGERVVMFDRCLVATGASPAVPPIPGLKD TPYWTSTEALVSESIPERLAVIGSSVVALELAQAFARLGSHVTILARGTLFLREDPAIGEAITAAFRAEGIEVLEHTQAS QVAYADGEFVLATGHGELRADKLLVATGRAPNTRRLNLEAAGVAINAQGAIVIDQGMRTNSPNIYAAGDCTDQPQFVYVA AAAGTRAAINMMGGSAALDLTAMPAVVFTDPQVATVGYSGAEAHRDGIETDSRTLTLDNVPRALANFNTRGFIKLVAEVG SGRLIGVQVVAPEAGELIQTAALAIRNRMTVQELADQLFPYLTMVEGLKLAAQTFTRDVKQLSCCAG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| merA | AGK07079.1 | MerA | Not tested | SGI1 | Protein | 0.0 | 80 |
| merA | ABQ57371.1 | MerA | Not tested | SGI1 | Protein | 0.0 | 80 |
| merA | AGK07021.1 | MerA | Not tested | SGI1 | Protein | 0.0 | 80 |
| merA | ACN81005.1 | MerA Hg(II) mercuric ion reductase | Not tested | AbaR5 | Protein | 0.0 | 80 |
| merA | CAJ77060.1 | Mercuric ion reductase | Not tested | AbaR1 | Protein | 0.0 | 80 |
| merA | AET25397.1 | MerA | Not tested | PAGI-2(C) | Protein | 0.0 | 79 |
| merA | AFG30120.1 | MerA | Not tested | PAGI-2 | Protein | 0.0 | 79 |
| merA | YP_006098387.1 | mercuric ion reductase | Not tested | Tn2411 | Protein | 0.0 | 79 |
| merA | AAN62178.1 | mercuric (Hg(II)) reductase | Not tested | PAGI-2(C) | Protein | 0.0 | 76 |
| unnamed | ABR13401.1 | mercuric reductase | Not tested | PAGI-5 | Protein | 0.0 | 73 |
| merA | BAB47642.1 | mercuric reductase | Not tested | Type-III SCCmec | Protein | 2e-93 | 41 |
| SE0085 | NP_763640.1 | dihydrolipoamide dehydrogenase | Not tested | SCCpbp4 | Protein | 2e-93 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| merA | YP_002426863.1 | mercuric reductase | BAC0653 | Protein | 0.0 | 81 |
| merA | YP_002426863.1 | mercuric reductase | BAC0652 | Protein | 0.0 | 79 |
| merA | YP_002426863.1 | mercuric reductase | BAC0650 | Protein | 2e-174 | 67 |
| merA | YP_002426863.1 | mercuric reductase | BAC0651 | Protein | 1e-93 | 41 |
| merA | YP_002426863.1 | mercuric reductase | BAC0224 | Protein | 3e-91 | 41 |
