Gene Information

Name : AFE_2421 (AFE_2421)
Accession : YP_002426807.1
Strain : Acidithiobacillus ferrooxidans ATCC 23270
Genome accession: NC_011761
Putative virulence/resistance : Resistance
Product : Cd(II)/Pb(II)-responsive transcriptional regulator
Function : -
COG functional category : K : Transcription
COG ID : COG0789
EC number : -
Position : 2167571 - 2168047 bp
Length : 477 bp
Strand : +
Note : identified by match to protein family HMM PF00376; match to protein family HMM PF09278; match to protein family HMM TIGR02047

DNA sequence : 
ATGCGAATCGGCGCACTTGGACAGGTGACCGGCGTGGATCCGGAGACCATCCGTTATTATGAGCGAATAGGCCTGTTGCC
CGCGCCAACCAGGCGGGCGAATGGTTATCGCGCTTATGGCCCCGCGCATCTGGAGCGACTTGCCTTTATTCGCCATTGCC
GGGCGCTGGATATGCCACTCGCGGATGTGCAGCGACTATTGCACTTGCTGGATCACCCACTGGACGATTGCCAAGACGTG
GATCGACTGATCGATACGCATCTGGCGCACGTACAGGGAAGACTCCAGTCCCTACAAGCGTTGGCGCGGCAGCTTGAGCA
ACTGCGCGGACGTTGCCATGGGCAACATGCAACCGCCGAATGCGGTATCCTGCATGAGTTGGTGGCCGCCGCCCAAGGGG
AAAACTGTATATGTCATGGCGGTTCGGTCCAGGCCCCCTTGAAGGATGTGCAGCGATCGGTAAGCCAAACAGGCTGA

Protein sequence : 
MRIGALGQVTGVDPETIRYYERIGLLPAPTRRANGYRAYGPAHLERLAFIRHCRALDMPLADVQRLLHLLDHPLDDCQDV
DRLIDTHLAHVQGRLQSLQALARQLEQLRGRCHGQHATAECGILHELVAAAQGENCICHGGSVQAPLKDVQRSVSQTG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadR ACS32041.1 MerR family transcriptional regulator Not tested AbaR5 Protein 1e-23 49
ACICU_00234 YP_001844893.1 transcriptional regulator Not tested AbaR20 Protein 1e-23 49
cadR ADZ05769.1 MerR family transcriptional regulator Not tested AbaR11 Protein 1e-23 49
pbrR CAJ77021.1 transcription regulator Not tested AbaR1 Protein 1e-23 49
pbrR CAJ77094.1 Transcriptional regulator Not tested AbaR1 Protein 8e-24 49
cadR AGK36653.1 MerR family transcriptional regulator Not tested AbaR26 Protein 8e-24 49
cadR ACN81029.1 MerR family transcriptional regulator Not tested AbaR5 Protein 1e-23 49
ORF C98 AAN62191.1 putative transcriptional regulator Not tested PAGI-2(C) Protein 5e-20 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
AFE_2421 YP_002426807.1 Cd(II)/Pb(II)-responsive transcriptional regulator BAC0058 Protein 2e-21 52
AFE_2421 YP_002426807.1 Cd(II)/Pb(II)-responsive transcriptional regulator BAC0301 Protein 7e-21 48