Gene Information

Name : AFE_2131 (AFE_2131)
Accession : YP_002426531.1
Strain : Acidithiobacillus ferrooxidans ATCC 23270
Genome accession: NC_011761
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase (NAD) family protein
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 1883674 - 1885194 bp
Length : 1521 bp
Strand : -
Note : identified by match to protein family HMM PF00171

DNA sequence :
ATGCAATATGCAAATCCAAATACCGAAGGCGCAGTCGTCAACTTCAAAGAACGCTATGACAACTTCATCGGCGGCCGGTG
GGTTGCCCCAGTCCGCGGTGAATACTTCGACAATATTTCCCCGATCAACGGCAAGCCGTTCTGCCAAATCCCCCGTTCCA
GCGCGGAAGATATTGAACTGGCATTGGATGCCGCCCACGCTGCCAAAGATGCCTGGGGCAGAACTTCCGTTACTGCCCGT
TCCAATATCCTGCTGAAAATCGCTGACCGCATTGACGCCAATCTGGAAATGCTGGCTGTGGCTGAAACCTGGGATAACGG
CAAAGCCGTGCGCGAAACTCTGAATGCGGACGTGCCGCTTTCCTCCGACCACTTCCGCTACTTCGCAGGCTGCTTACGCG
CTCAGGAAGGCACTATAGGTGAAATCGACGAAAATACCGTCGCTTACCACTTCCATGAGCCGCTGGGCGTCGTTGGTCAA
ATCATTCCGTGGAACTTCCCGCTGCTGATGGCGTGCTGGAAGCTGGCGCCCGCACTGGCGGCAGGTAACTGTGTGGTACT
GAAACCGGCAGAACAGACCCCCGCCTCCATTCTGGTGATGATGGAACTGATCGCCGACCTGTTGCCGGCAGGCGTGCTGA
ACGTGGTCAACGGCTACGGTGTGGAAGCAGGCAAAGCGCTGGCAACCAGCAAACGCATTGCCAAAATCGCCTTTACCGGC
TCTACCCCGGTCGGTTCCCTGATCATGAAATACGCGGCGGAAAACATTATCCCGTCTACCGTGGAACTGGGTGGCAAATC
CCCCAACATCTTCTTTGCCGACGTGCTGGATCAGGAAGATGCGTTTGTGAGCAAGGCGGTGGAGGGCGCGGTACTGGCAT
TCTTCAACCAAGGCGAAGTCTGCACTTGCCCTTCACGCCTGTTGATTCAAGAATCCATCTACGAAAAATTCATCGGCATG
GTGGTTGAGCGTTCAGCGCAAATCAAACGCGGCAATCCGTTGGATACTGAAGTCATGGTCGGTGCGCAAGCTTCCCAGGA
ACAGTACGACAAAATCCTCAGCTACATCCAGATCGGCAAGGACGAAGGCGCTGAAGTCATTACCGGTGGCGCGGTGGAAA
CCATGTCTGCGGATTACTGCGAAGGTTACTACATCCAACCTACCCTGCTGAAAGGCACCAACAACATGCGTGTGTTCCAA
GAAGAAATCTTCGGGCCGGTCGTGTCTGTGACAACCTTCAAGGACGAAGCGGAAGCATTGGCGATTGCCAACGACATCGA
GTTTGGTCTGGGCGCAGGCGTGTGGACTCGCGACATGAACCGTGCCTACCGCATGGGCCGTGGCATTCAGGCAGGTCGTG
TGTGGACCAACTGCTACCACATGTACCCAGCACATGCTGCCTTCGGTGGTTACAAAAAATCCGGCGTAGGCCGTGAAACC
CACAAAATGATGCTCGACCATTATCAGCAAACGAAAAACCTGCTGGTCAGCTACGACATCAATCCGTTGGGCTTTTTCTA
G

Protein sequence :
MQYANPNTEGAVVNFKERYDNFIGGRWVAPVRGEYFDNISPINGKPFCQIPRSSAEDIELALDAAHAAKDAWGRTSVTAR
SNILLKIADRIDANLEMLAVAETWDNGKAVRETLNADVPLSSDHFRYFAGCLRAQEGTIGEIDENTVAYHFHEPLGVVGQ
IIPWNFPLLMACWKLAPALAAGNCVVLKPAEQTPASILVMMELIADLLPAGVLNVVNGYGVEAGKALATSKRIAKIAFTG
STPVGSLIMKYAAENIIPSTVELGGKSPNIFFADVLDQEDAFVSKAVEGAVLAFFNQGEVCTCPSRLLIQESIYEKFIGM
VVERSAQIKRGNPLDTEVMVGAQASQEQYDKILSYIQIGKDEGAEVITGGAVETMSADYCEGYYIQPTLLKGTNNMRVFQ
EEIFGPVVSVTTFKDEAEALAIANDIEFGLGAGVWTRDMNRAYRMGRGIQAGRVWTNCYHMYPAHAAFGGYKKSGVGRET
HKMMLDHYQQTKNLLVSYDINPLGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-159 68
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 4e-169 67
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 4e-169 67
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 4e-169 67
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-168 67

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
AFE_2131 YP_002426531.1 aldehyde dehydrogenase (NAD) family protein VFG0082 Protein 7e-160 68