Gene Information

Name : AFE_0185 (AFE_0185)
Accession : YP_002424694.1
Strain : Acidithiobacillus ferrooxidans ATCC 23270
Genome accession: NC_011761
Putative virulence/resistance : Virulence
Product : type IV fimbriae expression regulatory protein PilR
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG2204
EC number : -
Position : 163903 - 165240 bp
Length : 1338 bp
Strand : +
Note : identified by similarity to SP:Q00934; match to protein family HMM PF00072; match to protein family HMM PF00158; match to protein family HMM PF02954

DNA sequence : 
TTGCCGCCCGCCCTGATCGTAGATGACGAGCCGGGCATCGTCGAACTGCTGGGCATTACGCTGCAGGGTATGGGGATCGC
TGTCACGGGCGCATATTCCCTTGCAGAAGCCCGCGCCCGCCTCGCCGAAGGCGCCCCTTCTTTATGTCTGAGCGATCTGC
GTTTGCCCGACGGTTCCGGTCTTGATCTGGTCCGCCGTTTGCGCGAGTTGTATCCACAAGTGCCGGTCGCCGTGATTACG
GCCTATTCTTCCGCCGATGGTGCCGTCGAAGCGATGCAGGCAGGGGCCTTCGATTACATGGCCAAGCCCATCGAACTGGC
GCGTCTGCGGCGATTGATATCCCAGGCCGTTGATCTCAGCCGCCTGTCCCCGGCGGGCCTGGGCGGCACGCAACGACTGG
TCGGCGATGCTCCGGTCATGCAGCGGTTGCGCGACGATATCCGCCGAGTAGCGCGGAGTAACGCGCCGGTACACATCACC
GGTAAGTCCGGTACGGGCAAGGAACTGGCCGCACGCGCCATTCACGCCTCGGGACCCCGTCACGACAAGCCCTTCGTGGC
CGTCAACTGCGGCGCCATTCCCGAGGGATTGGTGGAGAGTGAACTGTTCGGTGCCGAAAAGGGGGCTTATTCCGGTGCCG
TACAGCGTCGCGAAGGACTCTTTGCGGCGGCCAACGGGGGCACTATTTTTCTGGATGAGATCGGCGATCTGCCGATGATG
ATGCAGGTCAAGCTGCTGCGGGCCATTCAGGAACGGGCCATTCGCCCCCTGGGCGCGGCGCGGGAAATCTCCCTGGACCT
GCGCTTCATTTCCGCCACCCACCGTGACCTGCAGGAAATGGTTGCGGCCGGAAAGTTTCGTCAGGATCTCCGGTATCGTC
TGGATGTGGTAAGACTCCATATGCCGGCCCTGCGGGAACATCCGGAAGACATCCCGCAACTGGCAGAGGTGATTCTGCAA
CGTATCGGCGTGGCACCGCAGGATATTCCAGCGCTGCTGTCCCCAGGCACTTTGGAGCGGCTGGGTAGTTACGCCTTCCC
CGGCAACGTTCGCGAGTTGGAAAACTTTCTGGAGCGGAGCCTTGCCCTCAAGCAGGAAGGGATGCTGCTCGACGAAGGGA
TGTCCTCCCCCGCCGGCCCGGTGTCAAAAAGCAACGGGCCGGCGTTGGCACCGGTAATCGCCGTACCGGCCGCTTTTGAC
GCGGCGGAGGCCGCATTGCTGCGGCAGGTGCTCGATCAGGCCGAAGGGGATCGGCGTCATGCCGCCGTTCTGCTGGGGAT
CAGTCTGCAGTCGCTGGATCTGCGGCTGCACCGATTATTCCCGGAGGGTGACGCATGA

Protein sequence : 
MPPALIVDDEPGIVELLGITLQGMGIAVTGAYSLAEARARLAEGAPSLCLSDLRLPDGSGLDLVRRLRELYPQVPVAVIT
AYSSADGAVEAMQAGAFDYMAKPIELARLRRLISQAVDLSRLSPAGLGGTQRLVGDAPVMQRLRDDIRRVARSNAPVHIT
GKSGTGKELAARAIHASGPRHDKPFVAVNCGAIPEGLVESELFGAEKGAYSGAVQRREGLFAAANGGTIFLDEIGDLPMM
MQVKLLRAIQERAIRPLGAAREISLDLRFISATHRDLQEMVAAGKFRQDLRYRLDVVRLHMPALREHPEDIPQLAEVILQ
RIGVAPQDIPALLSPGTLERLGSYAFPGNVRELENFLERSLALKQEGMLLDEGMSSPAGPVSKSNGPALAPVIAVPAAFD
AAEAALLRQVLDQAEGDRRHAAVLLGISLQSLDLRLHRLFPEGDA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00300 YP_008207765.1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Not tested AbaR25 Protein 1e-74 45
BJAB0868_00304 YP_008211630.1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Not tested AbaR26 Protein 1e-74 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
AFE_0185 YP_002424694.1 type IV fimbriae expression regulatory protein PilR BAC0467 Protein 3e-72 47
AFE_0185 YP_002424694.1 type IV fimbriae expression regulatory protein PilR BAC0089 Protein 2e-66 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
AFE_0185 YP_002424694.1 type IV fimbriae expression regulatory protein PilR VFG1214 Protein 7e-95 49
AFE_0185 YP_002424694.1 type IV fimbriae expression regulatory protein PilR VFG0116 Protein 2e-54 41