Gene Information

Name : tkt-1 (AFE_1843)
Accession : YP_002426258.1
Strain : Acidithiobacillus ferrooxidans ATCC 23270
Genome accession: NC_011761
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 1601311 - 1603341 bp
Length : 2031 bp
Strand : +
Note : identified by match to protein family HMM PF00456; match to protein family HMM PF02779; match to protein family HMM PF02780; match to protein family HMM TIGR00232

DNA sequence :
ATGACAACTCCAACAGCCCCCTTTGGGGGGGAATACACATCCATTGATCAGCTTTCTATCAATACGATTCGCACGCTGGC
TATGGACGCTGTGCAACAGGCCGATTCAGGGCATCCAGGGACGCCCATGGCGTTGGCTCCAGCCGGCTACGTGCTATGGA
CGCGATTCCTTCGACACCATCCGTGCAATCCCATGTGGTTCAACCGGGACCGCTTCGTCTTATCGGCTGGGCATGCCTCC
ATGCTGCTGTATGCCTTACTCCATCTCAGCGGATATGACCTTTCACTCGAAGAAATCCGGCATTTTCGTCAATGGGGCAG
CAAGACTCCCGGACATCCGGAATACGGCCTCACTCCAGGGGTAGAAACCACCACTGGCCCTCTTGGTCAGGGCCTGATGA
ACGCGGTGGGCATGGCCATGGCCGAGGCCCATTTGGCAGCCCGCTTCAACCGGCCGGGATATGAAATCATCAATCACCAG
ACCTACGTTTTTTGTAGTGACGGCGATCTCATGGAGGGGGCATCCCACGAAGCCGCTTCCCTGGCTGGGCATTTAGCTTT
GGGCAAACTGATCGTGCTCTATGACGACAACCACATTACCATCGAAGGGAGTACGGCACTGGCCTTTTCCGACGACGTCG
CCCGGCGTTTCGACGCTTACCATTGGCATGTCCAAAACCTGGGCGAGGCGGCGAATGAGCTCGACACATTGGAGAACGCC
TTCCGTAATGCGCAGCAGGAAAGCAATCAGCCCTCCTTGATCATCGTCCGGTCTCATATCGCCTATGGCGCCCCTCATGC
CCAGGATACCGCCAAGGCCCATGGAGCCCCGTTGGGGGAAGCGGAGATTCGTGCCACGAAAGCGTTCTATGGATGGCCAC
CGGACGCCGGATTCCTCGTCCCGGATCCGGTGTTAATGCATATGCGTCAGGCTCAGGAGCGCGGGGCGGATCTGGAATCG
GCATGGAATCGGAAATTCGAAGCCTATCAGAAGGATTACCCCCAGGAGGGCGCCCATCTGATAGCGGCCATGGCGGGGGA
GCTTCCTGAAGGTTGGGACGAGAACATTCCCCACTTTACTCCTGAGGATGGCCCCATGGCGACTCGGGTGGCCTCCGAGA
AGACTTTGAACGCTTTTGCCGATAAGGTTCCCTGGTTGATGGGCGGTAGCGGAGATCTGGCGCCGTCCACCAATACCCGG
ATCGCCAGTTCCGGGGATTTTGAAAAAGACGGTTACAAAAATCGCAACATTCACTGGGGGGTGCGCGAGCACGTCATGTG
TGCCGCCTGTTCCGGTATGGCGCTCCATGGCGGGATTCGCCCTTATGGCGCAAGTTTTCTGATCTTCACCGACTATGCGC
GGCCGGCCATCCGTCTCGCCGCCATGATGAGGCTGCCCGTGATTTACGTGATGACCCACGATTCCATCGGTCTCGGGGAA
GATGGACCGACGCATCAACCGATAGAACATCTGGCGTCGTTCCGCGCCATGCCCAATCTGTGCGTAATCCGTCCAGCCGA
TGCCAACGAGGCGGCCTATGCGTGGCGTGCGGCCATCATCCGCCGGGACGGGCCTACGATGCTCGTCCTTACGCGGCAAT
CCCTTCCCGTATGGGACCGCAGCCTTCTCGGTGAGGCCAGAGGGAGCATGCAGGGGGCCTATGTGCTGTCCCGAGAACGG
GGCGGTCGCCCTCATATTCTTCTCCTAGCCAGCGGTTCCGAGGTGCAGCTCGTTCTGCAAGCCCAGGCCAAACTATACGA
GCGAGGAATAGATGCCCGGGTGGTCAGCATGCCCAGCTGGGAGCTGTTCCGCGCCCAGCCAGCGGCTTACCGGGATACGG
TGCTCCCACGAGATATCAAAGTCCGGCTCGCCGTAGAGGCTGCGGCATCCCTGGGGTGGTGCGAATGGGTGGGAGAGGGC
GCCACCATAGGCCTGAGCCGCTTCGGCGCCAGTGCACCCTATCCAGAAAATTTCCGCCATCTGGGATTCACCGTGGATAA
TGTGGTACAGGAAGCCCAACGGCTATTATAA

Protein sequence :
MTTPTAPFGGEYTSIDQLSINTIRTLAMDAVQQADSGHPGTPMALAPAGYVLWTRFLRHHPCNPMWFNRDRFVLSAGHAS
MLLYALLHLSGYDLSLEEIRHFRQWGSKTPGHPEYGLTPGVETTTGPLGQGLMNAVGMAMAEAHLAARFNRPGYEIINHQ
TYVFCSDGDLMEGASHEAASLAGHLALGKLIVLYDDNHITIEGSTALAFSDDVARRFDAYHWHVQNLGEAANELDTLENA
FRNAQQESNQPSLIIVRSHIAYGAPHAQDTAKAHGAPLGEAEIRATKAFYGWPPDAGFLVPDPVLMHMRQAQERGADLES
AWNRKFEAYQKDYPQEGAHLIAAMAGELPEGWDENIPHFTPEDGPMATRVASEKTLNAFADKVPWLMGGSGDLAPSTNTR
IASSGDFEKDGYKNRNIHWGVREHVMCAACSGMALHGGIRPYGASFLIFTDYARPAIRLAAMMRLPVIYVMTHDSIGLGE
DGPTHQPIEHLASFRAMPNLCVIRPADANEAAYAWRAAIIRRDGPTMLVLTRQSLPVWDRSLLGEARGSMQGAYVLSRER
GGRPHILLLASGSEVQLVLQAQAKLYERGIDARVVSMPSWELFRAQPAAYRDTVLPRDIKVRLAVEAAASLGWCEWVGEG
ATIGLSRFGASAPYPENFRHLGFTVDNVVQEAQRLL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 1e-138 50
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 1e-138 49