Gene Information

Name : guaA (AFE_1778)
Accession : YP_002426196.1
Strain : Acidithiobacillus ferrooxidans ATCC 23270
Genome accession: NC_011761
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1542291 - 1543835 bp
Length : 1545 bp
Strand : +
Note : identified by similarity to SP:P49057; match to protein family HMM PF00117; match to protein family HMM PF00958; match to protein family HMM TIGR00884; match to protein family HMM TIGR00888

DNA sequence :
ATGCAAGAACGTATCCTGATTCTCGATTTTGGTTCGCAGTTCACCCAGCTTATTGCGCGGCGGGTGCGCGAAGCGCACGT
CTATTGCGAAATTCACCCCTACAATATGGCGCTGGCGGAGATATGGGCTTGGCGGCCCAAGGGGATCATTCTGTCCGGAG
GGCCATCGTCGGTGCACGATGTCGATGCCCCATCCGTTGATCCTGCCCTGTTTGCCATGGGCTTGCCAGTCCTCGGTATT
TGTTACGGCCTGCAGTTGATGGCCCAGTTACTGGGTGGGCGGGTAGGCAAGGCGGAGCATCGGGAATACGGCCGCGCGCA
CCTTCAGATAAAGGAAGCGATCGGACCGTTTCTACCCTTTGGAGCGGCAGGCGCTGCCGAAGAAGTCTGGATGAGTCACG
GCGACCGGATAGAATCCATGCCCGATGGTTTCCGGGTGCTGGCCAGCAGCGCCAATTCACCGCTGGCGGCCATTGGCGAC
TCTGCACGCAACTTTTATGGTGTGCAGTTCCATCTGGAGGTCGCCCATACCCCCCGCGGCGCGGAGATGCTCACGGCCTT
CGTGCGCGGCGTATGCGGCTGCACTGGCGACTGGACCATGCACTCTTATGTGGACACGGCAGTGGCGACGATCCGTGCCC
AGGTGGGCAAGGGCCGGGTCATCGCCGCGCTTTCCGGCGGGGTGGATTCGGCCGTGGCGGTGGTGCTCATTCATCGCGCC
ATCGGCGACCAGCTTACCTGTATTTTTGTGGATAACGGGCTGTTGCGCTTTGGGGAAGCGGAGAAGGTGGCGACGGTCTT
TCGCAATTACTTTCAGATTCCCCTGCAGGTGGTGGATGCCCGGCAGCGTTTTCTGGATGTACTGGCGGATGTCACCGATC
CCGAAAAGAAGCGCAAGGCCATCGGTAATCTGTTCATCGAGATTTTTGAGGAAGAGTCGAAGCATCTGGAAGGCGCCGAT
TTCCTGGCGCAGGGTACCCTTTATCCTGACGTGATCGAGTCCATCTCGTTTAAGGGTCCCAGCGCGACCATCAAGTCTCA
CCATAACGTGGGTGGCTTGCCGGAGCGCATGCGCTTGCAACTGGTGGAGCCTTTGCGTGAGCTGTTCAAGGACGAAGTAC
GTGAACTCGGCCGTGAGCTGGGCATGCCCGAAGAAGTGATCCGGCGTCAGCCCTTCCCGGGGCCTGGTTTGGCCATCCGC
TGTCTGGGGGCGGTTGATGAACATCGCCTCGAAGTCCTGCGCCGTGCCGACCGTATCGTCATGGAAGAGATCCGTGATGC
CGGATTGTATGGTCGTCTCTGGCAGGCTTTTGCGGTATTGCTGCCGGTGCGCAGTGTCGGCGTGATGGGCGACGCGCGGA
CCTATGATGAAACCGTCGCCCTGCGCGCGGTGGAGTCGGCGGATGGCATGACCGCAGACTGGGCGCATATACCCTATGAA
GTGCTGGGACGCATCTCCACCCGGATCATCAACGAGGTCGCCGGGATCAATCGGGTGGTTTACGATATTTCATCCAAGCC
GCCGGCTACTATCGAGTGGGAGTGA

Protein sequence :
MQERILILDFGSQFTQLIARRVREAHVYCEIHPYNMALAEIWAWRPKGIILSGGPSSVHDVDAPSVDPALFAMGLPVLGI
CYGLQLMAQLLGGRVGKAEHREYGRAHLQIKEAIGPFLPFGAAGAAEEVWMSHGDRIESMPDGFRVLASSANSPLAAIGD
SARNFYGVQFHLEVAHTPRGAEMLTAFVRGVCGCTGDWTMHSYVDTAVATIRAQVGKGRVIAALSGGVDSAVAVVLIHRA
IGDQLTCIFVDNGLLRFGEAEKVATVFRNYFQIPLQVVDARQRFLDVLADVTDPEKKRKAIGNLFIEIFEEESKHLEGAD
FLAQGTLYPDVIESISFKGPSATIKSHHNVGGLPERMRLQLVEPLRELFKDEVRELGRELGMPEEVIRRQPFPGPGLAIR
CLGAVDEHRLEVLRRADRIVMEEIRDAGLYGRLWQAFAVLLPVRSVGVMGDARTYDETVALRAVESADGMTADWAHIPYE
VLGRISTRIINEVAGINRVVYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 5e-141 55
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-141 55
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-141 55
guaA NP_938969.1 GMP synthase Not tested Not named Protein 8e-127 53