Gene Information

Name : AFE_1742 (AFE_1742)
Accession : YP_002426162.1
Strain : Acidithiobacillus ferrooxidans ATCC 23270
Genome accession: NC_011761
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase (NAD) family protein
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 1508468 - 1509988 bp
Length : 1521 bp
Strand : +
Note : identified by match to protein family HMM PF00171

DNA sequence :
ATGATTTACGCAGCACCCGGCGCAGATGGCGCCAAGGTTAAATACAAGTCCAAGTACGACAATTTTATCGGCGGCAAGTG
GGTTGCCCCGGTCAAGGGCCAGTATTTTGATGTAATCACCCCGATCAATGGCAAGAGCTACACGCAGGCTGCCCGTTCTA
CCGCAGAAGACATCGAACTGGCGCTAGACGCTGCCCATGCCATAGCGGACAAGTGGGGCAAGACATCCCCCGCCGAGCGC
GCCAACATTCTTCTGAAAGTTGCTGACCGTATCGAAGCGAATCTCGAACTACTGGCTTATGCAGAGACCGTCGACAACGG
CAAGCCGATCCGCGAGACCCTCAACGCTGATATACCTCTGGCAGTTGATCACTTCCGTTATTTCGCCGGCTGCGTCCGCG
CTCAGGAGGGCGGTATCAGCGACATCGACGAGAACACTGTTGCTTACCACTTCCACGAGCCGCTCGGCGTTGTCGGCCAG
ATCATCCCGTGGAACTTCCCGATCCTGATGGCATCCTGGAAGCTAGCTCCCGCACTTGGCGCCGGCAACGTGGTGGTACT
CAAGCCAGCCGAATCGACCCCAATCAGCATCCTGATCCTGGCAGAGTTGATCGCCGACCTACTCCCTCCCGGCGTGCTGA
ACATCGTCAATGGCTATGGCCGCGAGGCTGGCATGCCGTTGGCCACCAGTAAGCGCATTGCCAAGATAGCCTTTACCGGT
TCGACTACTACGGGTCGTGTCATCGCCCAGGCAGCCGCCAACAGCCTAATCCCGGCGACGCTGGAACTTGGGGGCAAATC
GCCCAACATCTTCTTCGCCGATGTGATGGATAAGGACGACAGCTTCCTCGACAAGGCCATCGAAGGCCTCGTGCTGTTTG
CCTTCAATCAGGGCGAAGTCTGCACGTGCCCCTCGCGCGCTCTGATCCAAGAATCAATCTACGACAAGTTTATGGAACGC
TGCCTGGACCGCATCAAGGCTATCAAGCAGGGTAATCCTCTGGACACCAACACGATGATCGGAGCCCAGGCGTCCAAGGA
ACAGTTGACGAAAATCCTGTCCTATCTCGACCTCGGTAAGCAGGAAGGCGCTCAGGTGCTGATCGGTGGTTCGCAAGCGA
TTGTAGACGGTGATCTCGACGGCGGCTACTACGTCCAGCCGACCCTATTCAAGGGCCACAACAAGATGCGCATCTTCCAG
GAGGAAATTTTCGGGCCAGTGCTTGCTGTAACTACCTTTAAGGATGAAGCTGAAGCCTTATCTATCGCCAACGATACGCT
TTACGGTCTCGGTGCGGGTGTCTGGAGCCGCAACGGCAACGTCGCCTATCGCATGGGCCGTGCCATCAAGGCCGGGCGTG
TCTGGATTAACTGCTACCACGCTTATCCGGCGCATGCAGCCTTCGGCGGTTACAAGGAGTCGGGCATAGGTCGCGAGACC
CATAAAGTGATGCTCGACCACTACCAACAGACCAAGAACCTGCTGGTCAGCTACGCCGAGCAGAAACTGGGCTTCTTCTG
A

Protein sequence :
MIYAAPGADGAKVKYKSKYDNFIGGKWVAPVKGQYFDVITPINGKSYTQAARSTAEDIELALDAAHAIADKWGKTSPAER
ANILLKVADRIEANLELLAYAETVDNGKPIRETLNADIPLAVDHFRYFAGCVRAQEGGISDIDENTVAYHFHEPLGVVGQ
IIPWNFPILMASWKLAPALGAGNVVVLKPAESTPISILILAELIADLLPPGVLNIVNGYGREAGMPLATSKRIAKIAFTG
STTTGRVIAQAAANSLIPATLELGGKSPNIFFADVMDKDDSFLDKAIEGLVLFAFNQGEVCTCPSRALIQESIYDKFMER
CLDRIKAIKQGNPLDTNTMIGAQASKEQLTKILSYLDLGKQEGAQVLIGGSQAIVDGDLDGGYYVQPTLFKGHNKMRIFQ
EEIFGPVLAVTTFKDEAEALSIANDTLYGLGAGVWSRNGNVAYRMGRAIKAGRVWINCYHAYPAHAAFGGYKESGIGRET
HKVMLDHYQQTKNLLVSYAEQKLGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 5e-152 64
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 1e-161 63
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 1e-161 63
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 1e-161 63
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 6e-161 63

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
AFE_1742 YP_002426162.1 aldehyde dehydrogenase (NAD) family protein VFG0082 Protein 2e-152 64