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Name : topB (AFE_1738) Accession : YP_002426158.1 Strain : Acidithiobacillus ferrooxidans ATCC 23270 Genome accession: NC_011761 Putative virulence/resistance : Unknown Product : DNA topoisomerase III Function : - COG functional category : L : Replication, recombination and repair COG ID : COG0550 EC number : 5.99.1.2 Position : 1501586 - 1503685 bp Length : 2100 bp Strand : - Note : identified by match to protein family HMM PF01131; match to protein family HMM PF01751; match to protein family HMM TIGR01056 DNA sequence : ATGAAACTATACATCGCCGAGAAGCCCAGCCTGGGCAAAGGGATCGCCGAGTATTTGCCCGGATCGAAAAACAAAGGGAA CGGCTTCATCCAGTGCGGAGTGGATACCGTCGTAACCTGGTGTTTCGGCCATATCTTCGAGCAGGAAGAGCCGGACTTCT ATACGCCTGATGATGTTCCCACCACGCCAAAGGGCAAGAAGAAATGGCGATTTGAGGAACTGCCCATATTTCCTGAGCAA TGGAAGAAGCGGGCGAAGGATGACGCCAAGGCCCAGATCAAGGTGATCCGGGCCTTGCTCAAGAAAGCCTCGTCTGTCGT CAATGCAGGCGACCCGGACCGAGAGGGCCAGCTGCTGGTGGATGAGGTCCTGGAGGAACTCCGCTGGAAAGGACCAACCC TGAGGATCTGGCTGGCCGCCCTCGATGAGCAGTCCGTGCGTAAGGCGCTGGCATCGCTCAAGGATAACCACGACTACCAG AATCTCCGAAACTCAGCCGAAGCCCGTGCCCGCGCGGACTGGCTCATGGGCATGAATCTCACCCGTGCTTTCACCCTGCG CAACAGCGGCGCCGGAGTCGTCTCCGTGGGTCGGGTGCAGACGCCGACCTTGGCTCTGGTCGTGGCCCGTGATGAGAAGA TCGAGCACTTCAAGCCGAAGGACTACTACGTTCCGCGCATCAACGCGGGCTTCTGGGCCACCTGGGAGTTGCGGGAGGAT TTCGAGGGGGTCGATGCCGAAGGGTATCTCACCGACCGGAAAGCCGCTGACCGGCTGGCATCCCGGGCCAAGGCGGAAGG CAAGGCCACGGTGAAGGACTTCACCAGCGCGGAAAAGCAGCAGCAGGCACCATTAGGCTTCTCCCTTGCAGAGTTACAAA AGGTCTGCTCCGCCAAGCTCGGCATGTCGGCACAAAGTGTCCTTGATGCGGCCCAGGCGCTGTACGAGGAGCACAAGGCG GCGACCTATCCCCGGACCGATTGCCGCTATCTTCCGGAAGAACAGCATGGGGATGCCGGACAGATACTGTCCGGCCTGGC AAAAGCTGGATTTGCGGATCTGGTGAAAGCCGCCGATTCTAACCGGAAGTCGGCCATCTGGAATACGGGCAAAGTGACGG CGCACCACGCCATCATTCCGACCGGCTCCATGCAGGGCTCTATGAGCCCCGCAGTGGCCAAAGTCTACGATATCATCGTC CGCTCCTATCTCGCGCAGTTCTATCCGCCCTATGTGTACCGGGCGATCAAGGCTCTACTGACTTGCACCAGCGAGGACTG GAAGGCGACTGCCAACATCCCGGTATCCGCAGGCTGGAAAGCCGTGTATGGGATGACCGATGACGATAATGATGACACCC CCGCCCAGCCGATCCCGGCGCTCAAAAAAGGCCAGGTCCTGACCGTCCAGGATGCAGATGTCCAGGCAAAACAGACCAAG CCGCCGGCCCGATTTACGGATGGGTCGCTCATTGAGGCCATGAGCAACATCCATAAGGTGGTGGAGGATGAAGCCGCCAA GGCCAAACTCAAGGAAACCTCTGGCCTGGGAACCGAGGCCACTCGGGCCAGCATCATTGAAACGCTGCTGACCCGGGGAT TCCTGGAGCGCAAAGGCAAGCAGATCCTCTCCACCCAGGCAGGGCGGGCGCTGGTTCACGCGCTGCCCAAAGACCTGACC GATCCCGTCCTGACGGCACGCTGGGAAGATGCCCTGTCATCCGTGTCTGAGGGCCGCGTGACGCTACAGCAGTTCGAGGA AGCCCAGCGCAAATTCGTGGTGCGTATGATCGAGGCGGCCAAGGCGACGACCGTAGCTGTCGGCCAGGCACGGCCAACTT CCGGCGCTGGGCGTGGCAAGTCGTCTACCGGAAAAACGCGGGGCGTCGGACAAAAGACTGGCCCCGCCTGCCCGGACTGC AAGAAGCTGACCATCACCCTGAAGACGAAGAAGGGCGATGCCTTTTTCAAGTGCGAGGGCTGCCAGTCTTGCTGGTGGCC GGACAAGCAGGATGCCAAGAAGCTCGGAACGAAGTGGGGGCTAGAAAAGAATGAGTACGTTAGAAGAGAAGACTGGATTT CTCACACACAGCAGGATTGA Protein sequence : MKLYIAEKPSLGKGIAEYLPGSKNKGNGFIQCGVDTVVTWCFGHIFEQEEPDFYTPDDVPTTPKGKKKWRFEELPIFPEQ WKKRAKDDAKAQIKVIRALLKKASSVVNAGDPDREGQLLVDEVLEELRWKGPTLRIWLAALDEQSVRKALASLKDNHDYQ NLRNSAEARARADWLMGMNLTRAFTLRNSGAGVVSVGRVQTPTLALVVARDEKIEHFKPKDYYVPRINAGFWATWELRED FEGVDAEGYLTDRKAADRLASRAKAEGKATVKDFTSAEKQQQAPLGFSLAELQKVCSAKLGMSAQSVLDAAQALYEEHKA ATYPRTDCRYLPEEQHGDAGQILSGLAKAGFADLVKAADSNRKSAIWNTGKVTAHHAIIPTGSMQGSMSPAVAKVYDIIV RSYLAQFYPPYVYRAIKALLTCTSEDWKATANIPVSAGWKAVYGMTDDDNDDTPAQPIPALKKGQVLTVQDADVQAKQTK PPARFTDGSLIEAMSNIHKVVEDEAAKAKLKETSGLGTEATRASIIETLLTRGFLERKGKQILSTQAGRALVHALPKDLT DPVLTARWEDALSSVSEGRVTLQQFEEAQRKFVVRMIEAAKATTVAVGQARPTSGAGRGKSSTGKTRGVGQKTGPACPDC KKLTITLKTKKGDAFFKCEGCQSCWWPDKQDAKKLGTKWGLEKNEYVRREDWISHTQQD |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| topB | NP_458624.1 | topoisomerase B | Not tested | SPI-7 | Protein | 1e-105 | 42 |
| topB | NP_807836.1 | DNA topoisomerase III | Not tested | SPI-7 | Protein | 1e-105 | 42 |
| topB | AAF14809.1 | topoisomerase B | Not tested | SPI-7 | Protein | 1e-105 | 42 |
