Gene Information

Name : phoB (AFE_1434)
Accession : YP_002425862.1
Strain : Acidithiobacillus ferrooxidans ATCC 23270
Genome accession: NC_011761
Putative virulence/resistance : Virulence
Product : DNA-binding response regulator PhoB
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 1237096 - 1237827 bp
Length : 732 bp
Strand : +
Note : identified by similarity to SP:P45605; match to protein family HMM PF00072; match to protein family HMM PF00486; match to protein family HMM TIGR02154

DNA sequence : 
ATGGACGAAGACAAGGTATCCTCCCGTGTCCTGGTAGTGGAGGATGAGGAAGGCATTCAGGAACTCCTGCGCGTTACCCT
GCAGCGTAATGGCTTTGACGTTCGCTGTGAGGGCAGCGTCGAATCGGCGGAAGCGGTACTCCAGACCTGGGGGCCGCAGT
TGCTGGTGCTCGACTGGATGCTTCCCGGCAAAAATGGCCTGGCATGGTGCCGTATGCTGCGCCGTCGTGAAGAGACCCGG
AAGCTGCCCATCATCCTCCTTACCGCGCGCGGTGAAGAGGGTGACAGGGTGCATGGTCTGGAATCAGGTGCGGATGATTA
TCTGGCCAAACCCTTTTCTCCGCGGGAACTGGTGGCGCGGGTCAATGCCCTGCTGCGGCGCAGTTACGGTGGTACGGCGG
CGGGCCGGGTGCGGCTTGGCGGTCTGCAGGTGGATCTGCGCGCGCATCGGGTCTACGCCGATGAGGTACAGGTTCATCTC
GGGCCAACCGAGTTTCGTCTTTTGCGTCTTTTTGTGACCAATCCGGAACGGGTCTTTTCGCGGGATATGCTGCTCGATCA
GATCTGGGGGCGGCAGAGTTTTGTCGAAGAGCGCACGGTCGACGTCCACATTCGCCGCTTGCGTCGGGGGCTGGAGCACC
ACGGTTACGCCCAGATCATCGAAACTGTCAGGGGCGAAGGCTATCGCTGTAGTGCTTTGGGTTTCCAGCGGGAAGTGGTG
GACGAGCGATGA

Protein sequence : 
MDEDKVSSRVLVVEDEEGIQELLRVTLQRNGFDVRCEGSVESAEAVLQTWGPQLLVLDWMLPGKNGLAWCRMLRRREETR
KLPIILLTARGEEGDRVHGLESGADDYLAKPFSPRELVARVNALLRRSYGGTAAGRVRLGGLQVDLRAHRVYADEVQVHL
GPTEFRLLRLFVTNPERVFSRDMLLDQIWGRQSFVEERTVDVHIRRLRRGLEHHGYAQIIETVRGEGYRCSALGFQREVV
DER

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
c3565 NP_755440.1 response regulator Not tested PAI I CFT073 Protein 1e-31 43
unnamed CAD42044.1 hypothetical protein Not tested PAI II 536 Protein 3e-31 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
phoB YP_002425862.1 DNA-binding response regulator PhoB NC_010410.6002989.p0 Protein 1e-32 42
phoB YP_002425862.1 DNA-binding response regulator PhoB NC_011595.7057856.p0 Protein 1e-32 42
phoB YP_002425862.1 DNA-binding response regulator PhoB NC_010400.5986590.p0 Protein 8e-32 41
phoB YP_002425862.1 DNA-binding response regulator PhoB AE000516.2.gene3505. Protein 1e-35 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
phoB YP_002425862.1 DNA-binding response regulator PhoB VFG1702 Protein 4e-32 43
phoB YP_002425862.1 DNA-binding response regulator PhoB VFG1563 Protein 2e-31 42