Gene Information

Name : Mchl_0800 (Mchl_0800)
Accession : YP_002419647.1
Strain : Methylobacterium chloromethanicum CM4
Genome accession: NC_011757
Putative virulence/resistance : Resistance
Product : peptidase M15D vanX D-ala-D-ala dipeptidase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG2173
EC number : -
Position : 818165 - 818827 bp
Length : 663 bp
Strand : +
Note : PFAM: peptidase M15D vanX D-ala-D-ala dipeptidase; KEGG: mex:Mext_0840 peptidase M15D VanX D-ala-D-ala dipeptidase

DNA sequence :
ATGCGCGTTGCACTGACGGGCCTCGCCCTCGCCGCGTCCCAGCCGACCGCGGCGGAGACCGATCCCTTCGTCGATGCCGC
CCGGCACGTGCCGGGGCTCGCGCTCGACATGCGCTATGCCGGCTCCGACAACTTCGTCGGCCGGCCCATCGCCGGCTACG
AGGCACCGCGCTGCCTGCTCACCCCGCAGGCCGCCGGTGCGCTGGCCCGGGTGCAGGCGTCGCTGGCGCCGGACGGCCTC
GGCCTGAAGGTGTTCGATTGCTACCGCCCGCGCCAGGCGGTGGCCGACTTCGCCGCCTGGGCGCGCGACCCGGCCGACGC
ACGCATGAAGGCGGCCTACTACCCGCGGACGGACAAGGCGGATCTGTTCCGCCTCGGCTACATCGCTGAGCGCTCGTCGC
ATTCCCGCGGCTCCACCGTGGACCTGACGCTGGTGCGCAGCGCCGACGGCGTCGAACTCGACATGGGCACGCCGTTCGAC
CTGTTCGACCCGTCCTCGGCAACGGATTTTCCCGGCGTCAGCCCGATCCAGTCGCGCAACCGTCACCGCCTGCGCGACGC
GATGATTCGCGCCGGCTTCGTGCCCTACGCGCAGGAATGGTGGCACTTCACCCTCAAGGGCGAGCCCTACACCGACACGG
CCTTCGACCGGCCCGTCCGCTGA

Protein sequence :
MRVALTGLALAASQPTAAETDPFVDAARHVPGLALDMRYAGSDNFVGRPIAGYEAPRCLLTPQAAGALARVQASLAPDGL
GLKVFDCYRPRQAVADFAAWARDPADARMKAAYYPRTDKADLFRLGYIAERSSHSRGSTVDLTLVRSADGVELDMGTPFD
LFDPSSATDFPGVSPIQSRNRHRLRDAMIRAGFVPYAQEWWHFTLKGEPYTDTAFDRPVR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
vanX NP_815950.1 D-alanyl-D-alanine dipeptidase Not tested Not named Protein 2e-32 44
vanXB YP_008394260.1 D-alanyl-D-alanine dipeptidase Not tested Not named Protein 6e-32 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mchl_0800 YP_002419647.1 peptidase M15D vanX D-ala-D-ala dipeptidase U82965.2.orf32.gene. Protein 7e-39 47
Mchl_0800 YP_002419647.1 peptidase M15D vanX D-ala-D-ala dipeptidase FJ349556.1.orf5.gene Protein 3e-35 44
Mchl_0800 YP_002419647.1 peptidase M15D vanX D-ala-D-ala dipeptidase AE016830.1.gene2249. Protein 7e-33 44
Mchl_0800 YP_002419647.1 peptidase M15D vanX D-ala-D-ala dipeptidase U35369.1.gene7.p01 Protein 1e-32 44
Mchl_0800 YP_002419647.1 peptidase M15D vanX D-ala-D-ala dipeptidase M97297.gene.p01 Protein 6e-37 43
Mchl_0800 YP_002419647.1 peptidase M15D vanX D-ala-D-ala dipeptidase NC_014475.1.orf4.gen Protein 6e-37 43
Mchl_0800 YP_002419647.1 peptidase M15D vanX D-ala-D-ala dipeptidase NC_005054.2598281.p0 Protein 6e-37 43
Mchl_0800 YP_002419647.1 peptidase M15D vanX D-ala-D-ala dipeptidase AF310956.2.orf6.gene Protein 2e-32 43
Mchl_0800 YP_002419647.1 peptidase M15D vanX D-ala-D-ala dipeptidase AF130997.1.orf5.gene Protein 7e-32 43
Mchl_0800 YP_002419647.1 peptidase M15D vanX D-ala-D-ala dipeptidase AF155139.2.orf6.gene Protein 1e-32 43