Gene Information

Name : Mchl_5185 (Mchl_5185)
Accession : YP_002423875.1
Strain : Methylobacterium chloromethanicum CM4
Genome accession: NC_011757
Putative virulence/resistance : Virulence
Product : winged helix family two component transcriptional regulator PhoB
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 5549042 - 5549746 bp
Length : 705 bp
Strand : +
Note : TIGRFAM: phosphate regulon transcriptional regulator PhoB; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: mex:Mext_4718 phosphate regulon transcriptional regulator PhoB

DNA sequence : 
ATGACGAGTGCGCACATCCTGATCGTCGAGGACGAGGAATCGCTGACGACCCTGCTGCGCTACAATCTCGAAGCGGAGGG
TTTCCAAGTCGACGTCGCGGTTCGCGGCGACGAGGCCGACCTTCGCCTGCACGAGACCACGCCCGACCTCGTGCTGCTCG
ACTGGATGGTGCCGGGACTCTCGGGGATCGAGCTGTGCCGGCGCATCCGTGCCCGCCGTGAGACCGAACGCCTGCCGGTC
ATCATGCTGACCGCCCGGGGCGAAGAGACCGACCGTGTGCGCGGTCTCTCGACCGGCGCCGACGACTACGTCGTCAAGCC
GTTCTCCGTGCCGGAGTTGCTCGCCCGCGTCCGTGCGCTCCTGCGCCGGGCCAAGCCCACCCACGTCTCCGACATGCTCG
TGGCCGGCGATATCGAGCTCGACCGCGTCAGCCACCGCATCCGCCGGCAGGGCCGCGAGATCCATCTCGGCCCGACCGAG
TTCAAGCTGCTCGAATACCTGATGCAGAGCCCTGGCCGGGTCTTCTCGCGGGAGCAGTTGCTCGACGGCGTGTGGGGCCA
CGACGTCTACATCGACGAGCGCACGGTCGATGTTCATGTCGGCCGCCTGCGCAAGGCGATCAACCGCCCGCGCCAGAGCG
ACCCGATCCGCACCGTGCGCGGCTCCGGCTACTCGTTCGACGAGATGTTCGCCGGAGCGGAGTGA

Protein sequence : 
MTSAHILIVEDEESLTTLLRYNLEAEGFQVDVAVRGDEADLRLHETTPDLVLLDWMVPGLSGIELCRRIRARRETERLPV
IMLTARGEETDRVRGLSTGADDYVVKPFSVPELLARVRALLRRAKPTHVSDMLVAGDIELDRVSHRIRRQGREIHLGPTE
FKLLEYLMQSPGRVFSREQLLDGVWGHDVYIDERTVDVHVGRLRKAINRPRQSDPIRTVRGSGYSFDEMFAGAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD42044.1 hypothetical protein Not tested PAI II 536 Protein 5e-27 43
c3565 NP_755440.1 response regulator Not tested PAI I CFT073 Protein 5e-27 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mchl_5185 YP_002423875.1 winged helix family two component transcriptional regulator PhoB CP001485.1.gene721.p Protein 5e-23 44
Mchl_5185 YP_002423875.1 winged helix family two component transcriptional regulator PhoB NC_012469.1.7686381. Protein 7e-29 42
Mchl_5185 YP_002423875.1 winged helix family two component transcriptional regulator PhoB NC_012469.1.7685629. Protein 1e-26 42
Mchl_5185 YP_002423875.1 winged helix family two component transcriptional regulator PhoB AE000516.2.gene3505. Protein 3e-33 42
Mchl_5185 YP_002423875.1 winged helix family two component transcriptional regulator PhoB HE999704.1.gene2815. Protein 2e-29 41
Mchl_5185 YP_002423875.1 winged helix family two component transcriptional regulator PhoB NC_010400.5986590.p0 Protein 4e-27 41
Mchl_5185 YP_002423875.1 winged helix family two component transcriptional regulator PhoB NC_011595.7057856.p0 Protein 9e-28 41
Mchl_5185 YP_002423875.1 winged helix family two component transcriptional regulator PhoB HE999704.1.gene1528. Protein 6e-24 41
Mchl_5185 YP_002423875.1 winged helix family two component transcriptional regulator PhoB NC_010410.6002989.p0 Protein 9e-28 41
Mchl_5185 YP_002423875.1 winged helix family two component transcriptional regulator PhoB BAC0125 Protein 1e-22 41
Mchl_5185 YP_002423875.1 winged helix family two component transcriptional regulator PhoB CP000647.1.gene2531. Protein 5e-24 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mchl_5185 YP_002423875.1 winged helix family two component transcriptional regulator PhoB VFG1563 Protein 3e-27 43
Mchl_5185 YP_002423875.1 winged helix family two component transcriptional regulator PhoB VFG1702 Protein 2e-27 43
Mchl_5185 YP_002423875.1 winged helix family two component transcriptional regulator PhoB VFG1390 Protein 2e-25 42