Gene Information

Name : Mchl_4604 (Mchl_4604)
Accession : YP_002423306.1
Strain : Methylobacterium chloromethanicum CM4
Genome accession: NC_011757
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 4881281 - 4882567 bp
Length : 1287 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCACGACATCCGCGCCATCCGCGAGAACCCGGAGGCCTTCGACCGCGACCTGGAGCGGCGTGGCCTCGCGCCCCTCAG
CGCCGAGCTGATCGCCCTCGACGACGTGCGCAAGGGTGCGGTCTCGGCCGCACAGGCGGCCCAGGAGCGGCGCAACGCGC
TGTCCAAGGAGATCGGCGCCGCCAAGAAGGCCAAGGACGAGGCCCGTGCGACCGAGCTGATGGCCGAGGTCGCCCGCCTG
AAGGAAGAGGCACCGGGCCTCGAAGCCGCGCAGGGGGAGGCCGCCAAGGCCCTCGACGAGCGTCTCGCCGCGATCCCGAA
CCGTCCGAAGGACGACGTGCCCCCCGGCGCCGACGAGCACGGCAATGTCGAGTACCGCCGCTTCGATTCCTCCCGTGAGC
GCCTGACGCAAGGGCGTCAGCATTTCGAGCTCGGCGAGGCCACCGGGCTGATGGATTTCGAGGCGGCCGCGAAACTCTCC
GGCTCGCGCTTCGTCGTGCTGAAGGGCCAGCTCGCCCGGCTGGAGCGGGCGCTCGGCCAGTTCATGCTCGACCTGCACAC
GGGCGAGCACGGCTATACCGAGGTGGTGCCGCCGGTCCTCGTGCGTGAGGAAGCGATGTTCGGCACGGCGCAATTGCCGA
AGTTCCGTGATGATCAGTTCGCGGCGGGCGAGAACTTCTGGCTGATCCCCACGGCGGAAGTCCCGCTCACCAACCTCGTG
CGCGAAAGCATCCTCGCGGAGGACGAGCTTCCCTTGCGCTTCACCGCGCTCACCCCCTGCTTCCGCGCGGAGGCCGGGGC
GGCGGGGCGCGACACCCGCGGCATGCTGCGCCAGCACCAGTTCAACAAGGTCGAGCTGGTCTCGATCACCGCACCCGAAA
AGTCGGCCGAGGAGCACGAGCGGATGCTCGCCTGCGCCGAGGCCGTGCTGCAGAAGCTCGATCTCACCTATCGCGTCATG
ACGCTGTGTACCGGTGACATGGGCTTTGCCTCCCAGAAAACCTACGACATCGAGGTCTGGGTGCCGGGCCAGCAGACATA
CCGCGAGATTTCGTCCTGCTCGGTCTGCGGCGAGTTCCAGGCGCGGCGGATGAATGCGCGCTACCGGGCCAAGGAGGGCA
GGGGGGTCGGCTTCGTCCACACCCTGAACGGCTCGGGCGTCGCGGTCGGCCGCGCGCTGATCGCCGTGATGGAGAACTAC
CAGAACCCCGACGGCAGCGTCACGATCCCGTCGGCGCTCCAGCCCTACATGGGCGGCCTCACCCGGATCGAGGGACCGAA
GAACTGA

Protein sequence :
MHDIRAIRENPEAFDRDLERRGLAPLSAELIALDDVRKGAVSAAQAAQERRNALSKEIGAAKKAKDEARATELMAEVARL
KEEAPGLEAAQGEAAKALDERLAAIPNRPKDDVPPGADEHGNVEYRRFDSSRERLTQGRQHFELGEATGLMDFEAAAKLS
GSRFVVLKGQLARLERALGQFMLDLHTGEHGYTEVVPPVLVREEAMFGTAQLPKFRDDQFAAGENFWLIPTAEVPLTNLV
RESILAEDELPLRFTALTPCFRAEAGAAGRDTRGMLRQHQFNKVELVSITAPEKSAEEHERMLACAEAVLQKLDLTYRVM
TLCTGDMGFASQKTYDIEVWVPGQQTYREISSCSVCGEFQARRMNARYRAKEGRGVGFVHTLNGSGVAVGRALIAVMENY
QNPDGSVTIPSALQPYMGGLTRIEGPKN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 7e-98 51