Gene Information

Name : Mchl_4172 (Mchl_4172)
Accession : YP_002422894.1
Strain : Methylobacterium chloromethanicum CM4
Genome accession: NC_011757
Putative virulence/resistance : Resistance
Product : arsenical resistance protein ArsH
Function : -
COG functional category : R : General function prediction only
COG ID : COG0431
EC number : -
Position : 4398848 - 4399615 bp
Length : 768 bp
Strand : -
Note : TIGRFAM: arsenical resistance protein ArsH; PFAM: NADPH-dependent FMN reductase; KEGG: mex:Mext_3863 arsenical resistance protein ArsH

DNA sequence : 
GTGGACAAGTCCCATCAGCCGTTCGCCGACGGGTTGCCGAACCTCTCCGAGGCGCATGTCGAACTGCCCACCGCTGAGCG
GGTGCAGGCGTCGACGCCGCTCGCGCACGCGCCGCGCTTCCTGATCCTCTACGGTTCGCTCCGGGAGCGCTCCTTCAGCC
GGTTCCTGGCCTACGAGGCGGCCCGGTTGCTGGAGGCGATGGGCGGCGAGGTGCGGATCTTCCACGCGCACGGCCTGCCG
CTCCCCGACGACGCGACGGCAGACCACCCGAAGGTGCGGGAGCTCCGCGAACTCTCGGTCTGGTCCGAGGGGCAGGTCTG
GGTGAGCCCCGAGCGGCACGGCAACCTGACCGGGGTGATGAAAAGCCAGATCGATTGGCTGCCGCTGAGCGAGGGCTCGG
TCCGCCCGACGCAGGGGCGCACGCTTGCGGTGATGCAGGTGTCGGGCGGTTCGCAGAGCTTCAATGCGGTGAACAGCCTG
CGGGTGCTCGGGCGCTGGATGCGGATGATCACCATCCCGAACCAGTCCTCGGTGCCGATGGCCTACAAGGAGTTCGACGA
GGCCGGCCGCATGAGGCCGGGACCGCTCTACGACCGGGTCGTGGACGTGTGCGAGGAGCTGATGAAGTTCACGCTCCTGA
CCCGCGGACGGGCCGATTACCTCGTCGACCGCTACTCCGAGCGCAAGGAGCGTGAGCCCGACCGGCTCAAGGCGATTGCC
GCCGATGTGGGCTTTGTCCGGGCGCCATCCTCCGAGCGGGCATCGTAG

Protein sequence : 
MDKSHQPFADGLPNLSEAHVELPTAERVQASTPLAHAPRFLILYGSLRERSFSRFLAYEAARLLEAMGGEVRIFHAHGLP
LPDDATADHPKVRELRELSVWSEGQVWVSPERHGNLTGVMKSQIDWLPLSEGSVRPTQGRTLAVMQVSGGSQSFNAVNSL
RVLGRWMRMITIPNQSSVPMAYKEFDEAGRMRPGPLYDRVVDVCEELMKFTLLTRGRADYLVDRYSERKEREPDRLKAIA
ADVGFVRAPSSERAS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arsH YP_001007636.1 putative arsenic resistance protein Not tested YAPI Protein 1e-71 75
BCAM0236 YP_002232867.1 putative NADPH-dependent FMN reductase Not tested BcenGI11 Protein 1e-76 71
arsH AFC76432.1 ArsH Not tested AbaR5 Protein 3e-71 63
arsH CAJ77015.1 arsenic resistance protein Not tested AbaR1 Protein 2e-71 63
arsH ADZ05766.1 arsenic resistance protein Not tested AbaR11 Protein 2e-71 63

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mchl_4172 YP_002422894.1 arsenical resistance protein ArsH BAC0595 Protein 4e-63 67
Mchl_4172 YP_002422894.1 arsenical resistance protein ArsH BAC0034 Protein 2e-70 65