Gene Information

Name : Mchl_2886 (Mchl_2886)
Accession : YP_002421653.1
Strain : Methylobacterium chloromethanicum CM4
Genome accession: NC_011757
Putative virulence/resistance : Resistance
Product : dihydrofolate reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0262
EC number : 1.5.1.3
Position : 3035255 - 3035755 bp
Length : 501 bp
Strand : -
Note : PFAM: dihydrofolate reductase region; KEGG: mex:Mext_2659 dihydrofolate reductase

DNA sequence :
ATGGCTCAACCCCGCATCTCTCTGGTCGCAGCCATCGCCCGCAACGGCGTGATCGGCCGCGACAACAGCCTCGCGTGGCG
GCTTTCCAGCGACCTGAAGCGCTTCAAGGCGCTCACCATGGGCAAGCCGATCCTGATGGGGCGCAAGACCTGGGATTCGA
TCGGCCGCCCCCTGCCCGGACGCCGCAGTCTGGTCATCACCCGCGACCGCAGCCTCACCCTCTCCGACGTGACCGTCGTG
CATGATTGGGACGAAGCGCTCGCCGCCGCCGGGGACGACGAACTGATGGTGGTAGGCGGCGCCGAGATCTACAGGCTCGC
CCTGCCCCATGCCGACCGGCTGCATCTCACCGAAGTCGATGCGGCGCCTGAGGGCGATGCGTACTTTCCGCCCTTCGATC
GGTCTCTCTTCCGTGAGACGTTGCGCGAGGCGCACGGCCCCGGCGAGCGCGACGAGTTCGCGTTTCATTTCGTGGACTTG
GAGCGATTGGGCAGCCGTTGA

Protein sequence :
MAQPRISLVAAIARNGVIGRDNSLAWRLSSDLKRFKALTMGKPILMGRKTWDSIGRPLPGRRSLVITRDRSLTLSDVTVV
HDWDEALAAAGDDELMVVGGAEIYRLALPHADRLHLTEVDAAPEGDAYFPPFDRSLFRETLREAHGPGERDEFAFHFVDL
ERLGSR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dfrA12 ACF06156.1 dihydrofolate reductase Not tested Tn5036-like Protein 2e-21 47