Gene Information

Name : Mchl_1096 (Mchl_1096)
Accession : YP_002419923.1
Strain : Methylobacterium chloromethanicum CM4
Genome accession: NC_011757
Putative virulence/resistance : Resistance
Product : ATPase P
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 1107398 - 1109593 bp
Length : 2196 bp
Strand : -
Note : TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: haloacid dehalogenase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain

DNA sequence :
ATGAACCAAGCCGCCCCTACGGACCCGACATCATCTCCCACCACGGGCAATCAGGCCCTGCGCTACAGAGTCAAGGGCAT
GGACTGCCCAACCTGCGCCGGGAAGATCGAGAACGCCGTCTCCCGGCTGCCGGGTGTCGCGGACGTTCGCGTAAACTACG
GCAGCCAGGTTCTCGACCTGGCGCTCGACGAGGGCGTCACCCCGAGGACCGAGTTGGAGGGGCGCGTCGAACGCCTGGGC
TACGGCGTCGCGCCGCTGCCCACGGCCGCGGACCTGGCCAAGGCCCGGGCCGAGGGTGTCGCCCCGCCGGCCGGGACCAT
GGAGGATGCCGAACCGCCGCTCTGGCGGAGCCGCAAGGCGCTGCTGGGCATTCTCATCGGCACCCTGTTCGCCGCCGGGT
TCATCGTCGAGCGGATCGCGCCCGGCTTGGCGGGCGAGTACGCCTACTGGCCGGGGGCGCTCGTCGGGCTCGCCTATTAC
GGGCGCCGCGCGGTCGTGGCGGCCACGGCCGGCACGCCTTTCTCCATCGAGATGCTGATGTCGGTGGCGACGGCGGGGGC
GCTGGCCATCCATGCGGCCGAGGAGGCCGCCATCGTCGTCCTGCTCTTCACGGTCGGCGAGATGTTGGAGGTCGTGGCGG
CGGGGCGCGCACGCGCCGGCATCAAGGCGCTTGCGGCCCTGGTGCCTAAGACTGCCCGCCTCGTCGACGAAGCCGACGGC
ACGATCCGGGAGGTGCCCGCGGCGTCGCTCGCCATCGGGCAGGTCGTCGTGGTGAGGCCGGGCGACCGCGTGCCCGCCGA
CGGCGTGATCACGGATGGCTCGTCGAGCCTCGACGAGTCCCCCATCACCGGCGAGTCGGTCCCGAAGGCCAAGGAGGTTG
GTGACACGGTCTACGCCGGCAGCGTCAACGCCGACGGCGCACTCCAGGTCCGCGTCACCAAGACAGCGGCGGACAACACG
GTCGCCCGCATCCTCCACTTGGTCGAGGAGGCGCAGGCATCGAAGTCGCCCACGGCCCGCTTCATCGACCGGTTCAGCGC
GGTCTACACGCCCATCGCCTTCGCATTCGCGGCCGCCGTCGCGGTCCTGCCGCCGCTCCTCGGTGCCGACTGGGGCACTT
GGGTCTACCGGGGGCTCGCGCTCCTCCTCATCGCCTGCCCCTGCGCCCTCGTGCTCTCGACGCCGGCGGCCATCGCATCG
GGGTTGGCCGCCGGGGCGCGGCGCGGGCTGCTCGTGAAGGGCGGGGCGGCGCTGGAGGTCATCGGGCGGGTGCGCACGGT
GGCGTTCGACAAGACGGGAACCCTGACGGCTGGACGGCCGCGGGTCACCGACATCCTGGTCTTCGCGCCGGATGCGTCGG
AGCGCTCGCTTCTCGGATTGGCCGCCGCAGTCGAGAACGGGTCCAGCCATCCCATCGCCCGGGCCATCCTGGACCGGGCG
AACGAGGACGGGGTGCCGCTCCGGCCGACGCGCGATGCCCGCGCCACCCCCGGCAAGGCCGTGCAGGCCACGGTCATGGG
CCAGACGGTGCTTGTGGCCTCGCCGCGCCACGCCGCCGATAGCCTCCGGCTTGGCCCGGAGGCGGACCGTGCCGTCGCCG
GCCTGGAGACCAGTGGCAAGACGGTGGTCATCATCATCCGCGGCACCGAGGCACTGGGCGCCATCGCGGTCCGGGACGAG
CCCCGTGCCGACGCGGCCGCCGGCATCGCGGCCCTGCGGAAGCTGGGCGTGCGCAGCGTGATGCTGACCGGCGACAATCG
CCGCGCGGCCGAGGCGGTCGCGTCCGAACTCGGCCTCGACGTGAAGGCCGAGCTCCTGCCGCAAGACAAGCTCGCCGAGA
TCGCGGCCCTGAAGGAGGAGGGCCCGGTCGCGATGGTCGGCGACGGCATCAATGACGCGCCTGCCCTGGCCTCCGCCAGC
GTCGGCATCGCGATGGGCGGCGGCACGGACGCGGCCCTGGAAACGGCGGACGCCGCGGTGCTGAACGACCGCGTGGGAGA
CGTGGCCGCCCTCGTCGCCTTGTCCCGGGCGACGCTGGGAAACATCCGCCAGAACGTCGCCATCGCGCTCGGCCTGAAGG
CGGTGTTCCTGGTGACGACCATCGCCGGCATCACCGGCCTCTGGCCCGCCATCCTGGCCGATACCGGCGCGACCGTCCTG
GTGACGGCCAACGCGCTCCGTCTCCTGAGGGCATGA

Protein sequence :
MNQAAPTDPTSSPTTGNQALRYRVKGMDCPTCAGKIENAVSRLPGVADVRVNYGSQVLDLALDEGVTPRTELEGRVERLG
YGVAPLPTAADLAKARAEGVAPPAGTMEDAEPPLWRSRKALLGILIGTLFAAGFIVERIAPGLAGEYAYWPGALVGLAYY
GRRAVVAATAGTPFSIEMLMSVATAGALAIHAAEEAAIVVLLFTVGEMLEVVAAGRARAGIKALAALVPKTARLVDEADG
TIREVPAASLAIGQVVVVRPGDRVPADGVITDGSSSLDESPITGESVPKAKEVGDTVYAGSVNADGALQVRVTKTAADNT
VARILHLVEEAQASKSPTARFIDRFSAVYTPIAFAFAAAVAVLPPLLGADWGTWVYRGLALLLIACPCALVLSTPAAIAS
GLAAGARRGLLVKGGAALEVIGRVRTVAFDKTGTLTAGRPRVTDILVFAPDASERSLLGLAAAVENGSSHPIARAILDRA
NEDGVPLRPTRDARATPGKAVQATVMGQTVLVASPRHAADSLRLGPEADRAVAGLETSGKTVVIIIRGTEALGAIAVRDE
PRADAAAGIAALRKLGVRSVMLTGDNRRAAEAVASELGLDVKAELLPQDKLAEIAALKEEGPVAMVGDGINDAPALASAS
VGIAMGGGTDAALETADAAVLNDRVGDVAALVALSRATLGNIRQNVAIALGLKAVFLVTTIAGITGLWPAILADTGATVL
VTANALRLLRA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 1e-96 41
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 7e-97 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mchl_1096 YP_002419923.1 ATPase P BAC0461 Protein 9e-108 48
Mchl_1096 YP_002419923.1 ATPase P BAC0092 Protein 7e-71 42
Mchl_1096 YP_002419923.1 ATPase P BAC0124 Protein 1e-71 42