Gene Information

Name : cat (ECUMN_4806)
Accession : YP_002415399.1
Strain : Escherichia coli UMN026
Genome accession: NC_011751
Putative virulence/resistance : Resistance
Product : chloramphenicol acetyltransferase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG4845
EC number : 2.3.1.28
Position : 4986477 - 4987136 bp
Length : 660 bp
Strand : -
Note : Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 390404, 390403, 7353655; Product type e : enzyme

DNA sequence : 
ATGGAGAAAAAAATCACTGGATATACCACCGTTGATATATCCCAATGGCATCGTAAAGAACATTTTGAGGCATTTCAGTC
AGTTGCTCAATGTACCTATAACCAGACCGTTCAGCTGGATATTACGGCCTTTTTAAAGACCGTAAAGAAAAATAAGCACA
AGTTTTATCCGGCCTTTATTCACATTCTTGCCCGCCTGATGAATGCTCATCCGGAATTCCGTATGGCAATGAAAGACGGT
GAGCTGGTGATATGGGATAGTGTTCACCCTTGTTACACCGTTTTCCATGAGCAAACTGAAACGTTTTCATCGCTCTGGAG
TGAATACCACGACGATTTCCGGCAGTTTCTACACATATATTCGCAAGATGTGGCGTGTTACGGTGAAAACCTGGCCTATT
TCCCTAAAGGGTTTATTGAGAATATGTTTTTCGTCTCAGCCAATCCCTGGGTGAGTTTCACCAGTTTTGATTTAAACGTG
GCCAATATGGACAACTTCTTCGCCCCCGTTTTCACCATGGGCAAATATTATACGCAAGGCGACAAGGTGCTGATGCCGCT
GGCGATTCAGGTTCATCATGCCGTTTGTGATGGCTTCCATGTCGGCAGAATGCTTAATGAATTACAACAGTACTGCGATG
AGTGGCAGGGCGGGGCGTAA

Protein sequence : 
MEKKITGYTTVDISQWHRKEHFEAFQSVAQCTYNQTVQLDITAFLKTVKKNKHKFYPAFIHILARLMNAHPEFRMAMKDG
ELVIWDSVHPCYTVFHEQTETFSSLWSEYHDDFRQFLHIYSQDVACYGENLAYFPKGFIENMFFVSANPWVSFTSFDLNV
ANMDNFFAPVFTMGKYYTQGDKVLMPLAIQVHHAVCDGFHVGRMLNELQQYCDEWQGGA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cat CAJ77070.1 Chloramphenicol acetyltransferase Not tested AbaR1 Protein 1e-101 100
cat YP_006098370.1 chloramphenicol acetyltransferase Not tested Tn2411 Protein 2e-101 100
cat AAL08441.1 chloramphenicol acetyltransferase Not tested SRL Protein 6e-99 99
catA2 ACF06176.1 chloramphenicol acetyltransferase II Not tested Tn5036-like Protein 6e-47 46

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cat YP_002415399.1 chloramphenicol acetyltransferase NC_010558.1.6276004. Protein 8e-102 100
cat YP_002415399.1 chloramphenicol acetyltransferase NC_010410.6002590.p0 Protein 8e-102 100
cat YP_002415399.1 chloramphenicol acetyltransferase NC_011586.7045194.p0 Protein 8e-102 100
cat YP_002415399.1 chloramphenicol acetyltransferase CP004022.1.gene799.p Protein 5e-81 80

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cat YP_002415399.1 chloramphenicol acetyltransferase VFG1032 Protein 3e-99 99