Gene Information

Name : dnaB (ECUMN_4586)
Accession : YP_002415192.1
Strain : Escherichia coli UMN026
Genome accession: NC_011751
Putative virulence/resistance : Unknown
Product : replicative DNA helicase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0305
EC number : -
Position : 4757033 - 4758448 bp
Length : 1416 bp
Strand : +
Note : unwinds double stranded DNA

DNA sequence :
ATGGCAGGAAATAAACCCTTCAACAAACAGCAGGCTGAACCCCGCGAACGCGATCCACAAGTTGCCGGGCTGAAAGTGCC
TCCGCACTCGATCGAAGCGGAGCAGTCGGTGTTGGGCGGTTTAATGCTGGATAACGAACGTTGGGACGATGTAGCCGAGC
GTGTGGTGGCAGACGATTTTTACACCCGCCCACACCGTCATATCTTTACTGAAATGGCGCGTTTGCAGGAAAGCGGTAGT
CCTATCGATCTGATTACCCTTGCGGAATCGCTGGAACGCCAGGGGCAACTCGATAGCGTCGGTGGTTTTGCTTATCTGGC
AGAGTTGTCAAAAAATACGCCAAGTGCAGCGAACATCAGTGCCTATGCGGACATCGTGCGTGAACGTGCCGTTGTTCGCG
AGATGATTTCGGTTGCGAATGAGATTGCCGAAGCCGGTTTTGATCCGCAGGGGCGCACCAGCGAAGATCTGCTGGACCTG
GCTGAATCCCGCGTCTTTAAAATTGCCGAAAGTCGTGCAAACAAAGACGAAGGCCCGAAGAACATCGCCGATGTGCTCGA
CGCAACCGTGGCGCGTATTGAGCAGTTGTTTCAGCAGCCACACGATGGCGTTACCGGGGTAAACACCGGTTATGACGATC
TCAACAAAAAAACCGCTGGCTTGCAGCCGTCGGATTTGATCATCGTCGCCGCGCGTCCGTCGATGGGTAAAACGACATTT
GCGATGAACCTCGTCGAAAACGCGGCGATGTTGCAGGATAAACCGGTACTTATCTTCTCGCTGGAGATGCCATCAGAACA
GATTATGATGCGTACTCTGGCGTCGCTGTCGCGCGTTGACCAGACTAAAATCCGTACCGGGCAGCTCGATGATGAAGACT
GGGCGCGCATTTCCGGCACCATGGGTATTTTGCTCGAAAAACGTAATATCTATATCGATGACTCCTCCGGCCTGACGCCA
ACGGAAGTGCGTTCCCGCGCGCGCCGTATTGCCCGTGAACACGGCGGCATCGGGCTTATCATGATCGACTACCTGCAACT
GATGCGCGTACCGGCGCTTTCCGATAACCGTACGCTGGAAATTGCAGAAATCTCCCGCTCGCTGAAAGCACTGGCGAAAG
AATTGAACGTGCCGGTGGTGGCGCTGTCCCAGTTGAACCGTTCTCTGGAACAACGTGCCGACAAACGCCCGGTCAACTCC
GACCTGCGTGAATCTGGCTCTATCGAGCAGGATGCGGACTTGATCATGTTTATCTATCGTGATGAGGTGTATCACGAAAA
CAGTGATTTAAAAGGCATCGCGGAAATTATTATCGGTAAACAACGTAACGGCCCAATCGGGACGGTACGCCTGACCTTTA
ACGGTCAATGGTCGCGCTTCGACAACTATGCGGGGCCGCAGTACGACGACGAATAA

Protein sequence :
MAGNKPFNKQQAEPRERDPQVAGLKVPPHSIEAEQSVLGGLMLDNERWDDVAERVVADDFYTRPHRHIFTEMARLQESGS
PIDLITLAESLERQGQLDSVGGFAYLAELSKNTPSAANISAYADIVRERAVVREMISVANEIAEAGFDPQGRTSEDLLDL
AESRVFKIAESRANKDEGPKNIADVLDATVARIEQLFQQPHDGVTGVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTF
AMNLVENAAMLQDKPVLIFSLEMPSEQIMMRTLASLSRVDQTKIRTGQLDDEDWARISGTMGILLEKRNIYIDDSSGLTP
TEVRSRARRIAREHGGIGLIMIDYLQLMRVPALSDNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQRADKRPVNS
DLRESGSIEQDADLIMFIYRDEVYHENSDLKGIAEIIIGKQRNGPIGTVRLTFNGQWSRFDNYAGPQYDDE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
PMI2640 YP_002152342.1 DNA helicase Not tested Not named Protein 3e-106 55
dnaB2 YP_001402701.1 replicative DNA helicase Not tested YAPI Protein 3e-106 53
api2 CAF28476.1 putative DNA binding protein with DNA-dependent ATPase activity Not tested YAPI Protein 9e-107 53
dnaB2 YP_001007676.1 putative DNA helicase Not tested YAPI Protein 1e-106 53
dnaB CAI36044.1 replicative DNA helicase DnaB Not tested PPHGI-1 Protein 7e-88 50
unnamed ABR13456.1 replicative DNA helicase Not tested PAGI-5 Protein 7e-101 50
STY4522 NP_458617.1 DNA helicase Not tested SPI-7 Protein 9e-92 50
t4227 NP_807829.1 DNA helicase Not tested SPI-7 Protein 9e-92 50
dnaB1 YP_005176258.1 replicative DNA helicase Not tested ICEPmu1 Protein 7e-83 45