Gene Information

Name : arsB (ECUMN_3992)
Accession : YP_002414641.1
Strain : Escherichia coli UMN026
Genome accession: NC_011751
Putative virulence/resistance : Resistance
Product : arsenite/antimonite transporter
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1055
EC number : -
Position : 4098695 - 4099984 bp
Length : 1290 bp
Strand : +
Note : Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15004242, 95355341, 1535622, 7721697; Product type t : transporter

DNA sequence :
ATGTTACTGGCAGGCGCTATTTTTGTCCTGACCATCGTATTGGTTATCTGGCAGCCGAAAGGTTTAGGCATCGGCTGGAG
TGCAACGCTCGGCGCGGTACTGGCGTTGCTTACGGGCGTGGTTCATCCGGGTGATATTCCGGTGGTGTGGAATATCGTCT
GGAACGCGACGGCGGCGTTTATTGCCGTCATTATCATCAGCCTGCTGCTGGATGAGTCCGGCTTTTTTGAATGGGCGGCG
CTGCACGTCTCACGCTGGGGCAATGGACGCGGTCGCTTGCTGTTCACCTGGATTGTCCTGCTCGGTGCCGCCGTTGCAGC
TCTGTTTGCCAATGATGGCGCGGCGCTGATTTTAACGCCAATTGTCATCGCCATGCTGCTGGCTTTAGGATTCAGTAAAG
GCACTACGCTTGCGTTTGTGATGGCGGCCGGGTTCATTGCCGATACCGCCAGCCTGCCGCTTATTGTCTCCAACCTGGTG
AATATCGTTTCCGCAGATTTCTTTGGCCTCGGCTTTCGCGAATACGCATCGGTGATGGTGCCGGTGGATATCGCCGCAAT
TGTTGCCACGCTGGTGATGTTGCATCTTTATTTCCGCAAAGATATTCCGCAGAACTACGACATGGCGCTGCTGAAATCGC
CCGCAGAAGCGATTAAAGATCCTGCTACGTTCAAAACTGGCTGGTTTGTTTTACTGTTTCTGCTGGTGGGATTTTTCGTC
CTGGAACCGCTCGGCATTCCGGTAAGCGCCATTGCGGCAGTGGGCGCGCTGATATTATTTGCCGTCGCTAAACGCGGTCA
TGCAATTAATACGGGTAAAGTCCTGCGCGGTGCGCCCTGGCAGATTGTCATCTTCTCGCTCGGCATGTATCTGGTGGTTT
ATGGCCTGCGCAATGCCGGACTAACGGAATATCTTTCTGGCGTACTCAACGTGCTGGCGGAAAACGGCCTGTGGGCCGCG
ACGCTCGGCACCGGATTCCTCACCGCCTTCCTCTCTTCTATTATGAACAATATGCCGACGGTACTGGTTGGCGCGTTGTC
CATTGATGGCAGCACGGCATCTGGCGTTATCAAAGAAGCGATGGTTTATGCCAACGTGATTGGCTGCGATTTGGGACCGA
AAATTACCCCAATTGGTAGCCTGGCTACGCTACTCTGGCTGCACGTACTTTCGCAGAAGAATATGACTATCAGCTGGGGA
TATTACTTCCGTACAGGAATTATCATGACCCTGCCGGTGCTTTTTGTGACGCTGGCTGCGCTGGCGCTACGCCTCTCTTT
CACTTTGTAA

Protein sequence :
MLLAGAIFVLTIVLVIWQPKGLGIGWSATLGAVLALLTGVVHPGDIPVVWNIVWNATAAFIAVIIISLLLDESGFFEWAA
LHVSRWGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSKGTTLAFVMAAGFIADTASLPLIVSNLV
NIVSADFFGLGFREYASVMVPVDIAAIVATLVMLHLYFRKDIPQNYDMALLKSPAEAIKDPATFKTGWFVLLFLLVGFFV
LEPLGIPVSAIAAVGALILFAVAKRGHAINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNVLAENGLWAA
TLGTGFLTAFLSSIMNNMPTVLVGALSIDGSTASGVIKEAMVYANVIGCDLGPKITPIGSLATLLWLHVLSQKNMTISWG
YYFRTGIIMTLPVLFVTLAALALRLSFTL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arsB2 YP_001007633.1 arsenical pump membrane protein Not tested YAPI Protein 4e-157 92
arsB YP_005754065.1 arsenical pump membrane protein Not tested Type-XI SCCmec Protein 8e-95 59
arsB YP_252017.1 arsenical pump membrane protein Not tested SCCmec Protein 3e-95 59
SH0109 YP_252024.1 arsenical pump membrane protein Not tested SCCmec Protein 1e-98 59

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
arsB YP_002414641.1 arsenite/antimonite transporter BAC0576 Protein 2e-160 94
arsB YP_002414641.1 arsenite/antimonite transporter BAC0578 Protein 2e-161 94
arsB YP_002414641.1 arsenite/antimonite transporter BAC0031 Protein 1e-156 91
arsB YP_002414641.1 arsenite/antimonite transporter BAC0577 Protein 3e-155 90
arsB YP_002414641.1 arsenite/antimonite transporter BAC0574 Protein 2e-96 60
arsB YP_002414641.1 arsenite/antimonite transporter BAC0575 Protein 9e-100 60