Gene Information

Name : kpsC (ECUMN_3423)
Accession : YP_002414088.1
Strain : Escherichia coli UMN026
Genome accession: NC_011751
Putative virulence/resistance : Virulence
Product : Capsule polysaccharide export protein
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG3563
EC number : -
Position : 3534549 - 3536576 bp
Length : 2028 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8397187, 8326861; Product type t : transporter

DNA sequence :
ATGATTGGCATTTACTCGCCTGGCATCTGGCGTATTCCGCATCTGGAGAAATTTCTGGCGCAACCGTGCCAGAAACTTTC
TCTGCTGCGCCCTGTTCCACAAGAAGTTGATGCTATCGCCGTGTGGGGACATCGTCCCAGCGCGGCGAAACCAGTCGCCA
TCGCCAAAGCAGCGGGAAAACCCGTCATTCGTCTGGAAGATGGATTTGTGCGTTCGCTGGATCTTGGCGTCAATGGCGAG
CCGCCGCTTTCTCTGGTGGTGGATGATTGTTGCATTTACTACGATGCCAGCAAGCCTTCAGCACTGGAGAAACTGGTACA
GGATAAAGCCGGAAATACAGCTCTGATAAGCCAGGCCAGAGAAGCGATGCACACCATCGTGACCGGGGATTTGTCGAAAT
ATAACCTGGCACCTGCGTTTGTGGCTGATGAGTCAGAACGTTCAGACATCGTTCTGGTTGTCGATCAGACATTTAATGAT
ATGTCAGTGACGTATGGCAATGCTGGCCCGCATGAGTTTGCTGCCATGCTGGAAGCCGCGATGGCGGAAAATCCTCAAGC
CGAAATTTGGGTGAAGGTGCATCCGGATGTCCTGGAAGGAAAGAAAACAGGTTATTTCGCCGCTCTGCGCGCCACGCAAC
GAGTACGTTTAATTGCCGAGAATGTCAGCCCGCAGTCGCTGTTGCGACACGTTTCCCGGGTTTACGTCGTGACCTCCCAG
TACGGCTTTGAAGCCTTGCTGGCAGGAAAACCGGTGACATGCTTCGGCCAGCCCTGGTATGCAGGCTGGGGCTTAACCGA
CGATCGCCATCCGCAGTCCGCTTTGTTATCTGCCCGACGCGGTTCTGCCACGCTGGAGGAACTTTTTGCCGCTGCATACC
TGCGTTACTGTCGCTATATCGATCCGCAAACGGGAGAAGTAAGCAATCTATTTACCGTGCTGCAATGGCTGCAATTACAA
CGTCGACATCTGCAACAGCGTAATGGTTATTTATGGGCGCCAGGCTTAACGCTGTGGAAGTCAGCGATCCTGAAACCTTT
CTTGCAAACGGCAACAAACCGGCTGAGTTTTTCACGTCGCTGTACTGCGGCGAGCGCCTGCGTGGTATGGGGTGTAAAGG
GAGAACAGCAATGGCGAGCCGAAGCGCAGCGAAAATCACTGCCGTTATGGCGAATGGAAGATGGTTTTCTACGTTCATCC
GGACTTGGCTCTGACCTTTTGCCGCCGCTATCGTTGGTCCTGGATAAACGCGGGATCTACTATGACGCCACGCGCCCCAG
CGACCTGGAAGTGCTGCTTAATCACAGCCAGTTAACACTGGCGCAGCAGATGCGAGCTGAAAAATTACGCCAGCGACTGG
TTGAAAGCAAACTGAGCAAATACAACCTGGGGGCCGATTTCTCTCTGCCTGCCGAGGCCAAAGATAAAAAAATCATCCTG
GTGCCGGGTCAGGTAGAAGACGATGCCTCAATTAAAACAGGCACTGTGTCGATTAAGAGCAACCTTGAGTTATTACGCAC
AGTACGCGAGCGCAATCCGCACGCTTACATTATTTATAAACCGCACCCGGATGTACTGGTGGGGAATCGCAAGGGCAATA
TTCCGACAGAACTAATTGCTGAACTCGCTGATTATCAGGCACTGGACGCAGATATTATTCAATGCATTCAGCGCGCAGAT
GAAGTGCACACCATGACATCATTGTCCGGGTTTGAAGCGTTATTACATGGCAAGCAAGTTCATTGTTACGGCCTGCCCTT
CTATGCCGCTTGGGGTTTAACCGTTGATGAACATCATTGCCCGCGCCGCGAGCGCAGATTAACGATAGCAGACTTGATCT
ATCAGGCGTTGATTGTTTACCCAACATATATTCATCCAACACGGCTACAGCCTATTACGGTTGAGGAAGCTGCGGAATAT
TTAATCCAGACGCCGCGTAAGCCGATGTTTATTACCCGAAAAAAAGCGGGGCGGGTAATACGCTATTGCCGCAAATTAAT
TATGTTCTGCAAGGTCAGATTTGGCTAA

Protein sequence :
MIGIYSPGIWRIPHLEKFLAQPCQKLSLLRPVPQEVDAIAVWGHRPSAAKPVAIAKAAGKPVIRLEDGFVRSLDLGVNGE
PPLSLVVDDCCIYYDASKPSALEKLVQDKAGNTALISQAREAMHTIVTGDLSKYNLAPAFVADESERSDIVLVVDQTFND
MSVTYGNAGPHEFAAMLEAAMAENPQAEIWVKVHPDVLEGKKTGYFAALRATQRVRLIAENVSPQSLLRHVSRVYVVTSQ
YGFEALLAGKPVTCFGQPWYAGWGLTDDRHPQSALLSARRGSATLEELFAAAYLRYCRYIDPQTGEVSNLFTVLQWLQLQ
RRHLQQRNGYLWAPGLTLWKSAILKPFLQTATNRLSFSRRCTAASACVVWGVKGEQQWRAEAQRKSLPLWRMEDGFLRSS
GLGSDLLPPLSLVLDKRGIYYDATRPSDLEVLLNHSQLTLAQQMRAEKLRQRLVESKLSKYNLGADFSLPAEAKDKKIIL
VPGQVEDDASIKTGTVSIKSNLELLRTVRERNPHAYIIYKPHPDVLVGNRKGNIPTELIAELADYQALDADIIQCIQRAD
EVHTMTSLSGFEALLHGKQVHCYGLPFYAAWGLTVDEHHCPRRERRLTIADLIYQALIVYPTYIHPTRLQPITVEEAAEY
LIQTPRKPMFITRKKAGRVIRYCRKLIMFCKVRFG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsC YP_854335.1 capsule polysaccharide export protein KpsC Not tested PAI I APEC-O1 Protein 0.0 97
kpsC AAZ04470.1 capsule polysaccharide export protein Virulence PAI I APEC-O1 Protein 0.0 97
lipA NP_273145.1 capsule polysaccharide modification protein Not tested IHT-A Protein 1e-126 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
kpsC YP_002414088.1 Capsule polysaccharide export protein VFG0259 Protein 6e-127 50
kpsC YP_002414088.1 Capsule polysaccharide export protein VFG0692 Protein 2e-117 47
kpsC YP_002414088.1 Capsule polysaccharide export protein VFG0704 Protein 7e-105 47