Gene Information

Name : iucD (ECUMN_3372)
Accession : YP_002414043.1
Strain : Escherichia coli UMN026
Genome accession: NC_011751
Putative virulence/resistance : Virulence
Product : L-lysine 6-monooxygenase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG3486
EC number : 1.14.13.59
Position : 3486493 - 3487830 bp
Length : 1338 bp
Strand : -
Note : Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3275632, 10064136; Product type e : enzyme

DNA sequence :
ATGAAAAAAAGTGTCGATTTTATTGGTGTCGGGACAGGGCCATTTAATCTCAGTATTGCTGCATTGTCACATCAGATCGA
AGAACTGAACTGTCTCTTCTTTGACGAACATCCTCATTTTTCCTGGCATCCGGGTATGCTGGTACCGGATTGTCATATGC
AGACTGTCTTTCTGAAAGATCTGGTCAGTGCAGTTGCACCTACAAATCCCTACAGCTTTGTTAACTATCTGGTGAAGCAC
AAAAAGTTCTATCGCTTCCTTACAAGCAGACTACGTACAGTATCCCGTGAAGAGTTTTCTGACTATCTCCGCTGGGCTGC
TGAAGATATGAATAACCTGTATTTCAGTCATACCGTTGAAAATATTGATTTCGACAAAAAAAGTCGATTGTTTCTGGTTC
AGACCAGTCGGGGAGAATATTTTGCCCGCAATATCTGCCTTGGTACAGGAAAACAACCTTATTTACCACCCTGTGTGAAG
CATGTGACACAATCCTGTTTCCATGCCAGTGAAATGAATCTTCGTCGGCCGGACCTGAGTGGAAAACGGATAACTGTGGT
TGGTGGAGGACAGAGTGGTGCAGACCTGTTCCTTAATGCATTACGCGGGGAATGGGGAGAAGCGGCGGAAATAAACTGGG
TCTCACGGCGTAATAATTTTAACGCACTGGATGAGGCTGCTTTTGCTGATGAGTATTTTACACCTGAATATATTTCAGGC
TTCTCCGGACTGAAGGAAGATATTCGCCATCAGTTACTGGATGAGCAGAAAATGACATCGGATGGCATCACTGCCGATTC
TTTACTGACCATTTATCGTGAGTTGTACCACCGTTTTGAAGTTCTGAGAAAACCAAGAAATATCCGTCTGCTACCCAGCC
GCTCGGTAACAACTCTGGAAAGTAGTGGTCCGGGCTGGAAGTTATTGATGGAACATCATCTGGATCGGGGCAGAGAGAGC
CTGGAAAGTGATGTGGTGATTTTCGCCACAGGTTACCGTTCTGCATTGCCACAAATACTTCCCTCACTGATGCCCTTGAT
CACCATGCACGATAAGAACACCTTTAAAGTGCGTGATGACTTCACTCTGGAATGGAGTGGCCCGAAAGAAAATAACATCT
TTGCGGTCAACGCCAGCATGCAAACTCATGGCATCGCCGAACCCCAGCTCAGCCTGATGGCCTGGAGATCTGCACGTATT
CTTAATCGCGTACTGGGGCGTGATTTATTCGATCTCAGTATGCCGCCCGCACTGATTCAGTGGCGCAGCGGCAGCCGGAA
AAAACCGCAGCCGGAGGCTGCTGCTTTAACTCACTATACAACAAATATTCAGGAATAA

Protein sequence :
MKKSVDFIGVGTGPFNLSIAALSHQIEELNCLFFDEHPHFSWHPGMLVPDCHMQTVFLKDLVSAVAPTNPYSFVNYLVKH
KKFYRFLTSRLRTVSREEFSDYLRWAAEDMNNLYFSHTVENIDFDKKSRLFLVQTSRGEYFARNICLGTGKQPYLPPCVK
HVTQSCFHASEMNLRRPDLSGKRITVVGGGQSGADLFLNALRGEWGEAAEINWVSRRNNFNALDEAAFADEYFTPEYISG
FSGLKEDIRHQLLDEQKMTSDGITADSLLTIYRELYHRFEVLRKPRNIRLLPSRSVTTLESSGPGWKLLMEHHLDRGRES
LESDVVIFATGYRSALPQILPSLMPLITMHDKNTFKVRDDFTLEWSGPKENNIFAVNASMQTHGIAEPQLSLMAWRSARI
LNRVLGRDLFDLSMPPALIQWRSGSRKKPQPEAAALTHYTTNIQE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
iucD YP_002414043.1 L-lysine 6-monooxygenase Virulence Not named Protein 0.0 100
iucD NP_709457.1 lysine:N6-hydroxylase Virulence SHI-2 Protein 0.0 99
iucD AAD44749.1 IucD Virulence SHI-2 Protein 0.0 99
iucD NP_839220.1 lysine:N6-hydroxylase Virulence SHI-2 Protein 0.0 99
iucD AAK71634.1 IucD Virulence SHI-3 Protein 0.0 98

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
iucD YP_002414043.1 L-lysine 6-monooxygenase VFG0937 Protein 0.0 100
iucD YP_002414043.1 L-lysine 6-monooxygenase VFG0618 Protein 0.0 99
iucD YP_002414043.1 L-lysine 6-monooxygenase VFG1084 Protein 0.0 98