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Name : spaS (ECUMN_3194) Accession : YP_002413878.1 Strain : Escherichia coli UMN026 Genome accession: NC_011751 Putative virulence/resistance : Virulence Product : surface presentation of antigens protein SpaS Function : - COG functional category : N : Cell motility COG ID : COG1377 EC number : - Position : 3307071 - 3308183 bp Length : 1113 bp Strand : - Note : Required for surface presentation of invasion plasmid antigens; required for invasion and for secretion of the three ipa proteins DNA sequence : ATGGCAAATAAAACTGAAAAGCCAACACAAAAGAAACTCCAGGATGCTTCTAAAAAAGGTCAAATTCTAAAAAGTAGAGA CTTAACAGTCTCTGTAATAATGCTTGTGGGTACTTTATATCTCGGATATGTATTTGATGTGCATCACATTATGTCGATTC TTGAATACATCCTTGATCATAACGCTAAACCGGATATTTGGGACTATTTTAAAGCTATGGGGATAGGTTGGTTGAAAACG ATCATTCCTTTTTTGCTGGTTTGTATGTTTACAACAATACTTGTTTCATGGTTTCAAAGTAAAATGCAATTAGCAACTGA AGCTATTAAGTTTAAGTTTGATTCATTAAATCCAGTAAATGGCTTAAAACGTATATTTGGCTTAAAAACCGTAAAAGAAT TTGTTAAAGCAATACTTTATATTATTTTTTTTGCATTGGCGATCAAATTATTTTGGAGTAACCATAAATCACTGCTTTTT AAAACTCTTGATGGAGATATCATTTCTTTATTATCAGATTGGGGAGAGATGCTATTCCTTCTCATACTGTATTGTCTCGG CAGTATGATAATTGTCTTAATTTTTGATTTTATCGCTGAATATTTTTTATTTATGAAAGATATGAAAATGGATAAACAAG AAGTTAAAAGAGAATACAAGGAACAAGAAGGAAGTCCAGAAATTAAGTCTAAACGCAGAGAGCGCCATCAAGAAATTCTT TCTGAGCAATTGAAATCTGATGTCAGTAATAGCCGTTTGATGATTGCCAACCCTACTCACATTGCCATAGGGATATACTT TAAGCCACATCTGTCACCTATCCCATTGATTTCTGTAAGAGAAACTAATGAGGTAGCATTAGCCGTAAGGAAATATGCAA AGGAAATCGGGATACCAATTATTACAGATAAAAAATTAGCACGAAAAATTTATGCTACCCATCGTCGCTACGATTATGTG AGCTTCGAAAATATAGATGAAATATTACGTCTTCTGCTGTGGCTTGAAGATGTGGAGAATGCCGGACAACCTGTTCCAGA TGAACAGTTCTCTTCAGAAGATAAATTCATTGAGGGTGAAGACACAGAAATCGAGAATAAAGATAATAATTGA Protein sequence : MANKTEKPTQKKLQDASKKGQILKSRDLTVSVIMLVGTLYLGYVFDVHHIMSILEYILDHNAKPDIWDYFKAMGIGWLKT IIPFLLVCMFTTILVSWFQSKMQLATEAIKFKFDSLNPVNGLKRIFGLKTVKEFVKAILYIIFFALAIKLFWSNHKSLLF KTLDGDIISLLSDWGEMLFLLILYCLGSMIIVLIFDFIAEYFLFMKDMKMDKQEVKREYKEQEGSPEIKSKRRERHQEIL SEQLKSDVSNSRLMIANPTHIAIGIYFKPHLSPIPLISVRETNEVALAVRKYAKEIGIPIITDKKLARKIYATHRRYDYV SFENIDEILRLLLWLEDVENAGQPVPDEQFSSEDKFIEGEDTEIENKDNN |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| ECs3721 | NP_311748.1 | surface presentation of antigens protein SpaS | Not tested | LIM | Protein | 3e-160 | 98 |
| spaS | NP_461808.1 | surface presentation of antigens protein SpaS | Virulence | SPI-1 | Protein | 4e-76 | 55 |
| spaS | NP_806490.1 | surface presentation of antigens protein SpaS | Virulence | SPI-1 | Protein | 6e-76 | 54 |
| spaS | YP_217806.1 | surface presentation of antigens protein SpaS | Virulence | SPI-1 | Protein | 7e-75 | 54 |
| spaS | NP_457281.1 | secretory protein (associated with virulence) | Virulence | SPI-1 | Protein | 6e-76 | 54 |
| spaS | AAS66868.1 | SpaS | Not tested | SSR-2 | Protein | 8e-67 | 47 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| spaS | YP_002413878.1 | surface presentation of antigens protein SpaS | VFG0548 | Protein | 2e-76 | 55 |
| spaS | YP_002413878.1 | surface presentation of antigens protein SpaS | VFG1015 | Protein | 3e-74 | 53 |
| spaS | YP_002413878.1 | surface presentation of antigens protein SpaS | VFG2452 | Protein | 7e-58 | 42 |
