Gene Information

Name : eprK (ECUMN_3188)
Accession : YP_002413872.1
Strain : Escherichia coli UMN026
Genome accession: NC_011751
Putative virulence/resistance : Virulence
Product : putative type III secretion system lipoprotein EprK
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG4669
EC number : -
Position : 3303429 - 3304163 bp
Length : 735 bp
Strand : -
Note : Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12791847; Product type pm : putative membrane component

DNA sequence :
ATGAAATATATATCATTATTCTTGTTTATCCTGCTGTTGTGCGGTTGCAAGCAGCAGGAATTACTGAACCATCTTGATCA
ACAGCAAGCTAATGATGTCCTTGCTGTTTTACAAAGACATAATATTAATGCTGAGAAGAAGGATCAAGGCAAAACTGGAT
TTTCAATCTATGTAGAACCAACGGATTTTGCTTCTGCGGTGGATTGGCTAAAAATCTACAATCTCCCGGGTAAGCCTGAT
ATTCAAATATCGCAGATGTTCCCTGCAGATGCACTCGTTTCCTCTCCACGAGCGGAAAAAGCAAGATTGTATTCTGCTAT
TGAACAGCGTTTAGAGCAATCTCTCAAAATTATGGATGGCATTGTTTCTTCAAGAGTACATGTTAGTTACGATGTTGATA
CAGGTGATAGTGGCAAAACTGCTTTACCAATTCATATTTCTGTACTTGCTGTATATGAAAAAGATATCAATCCAGAAATA
AAAATAAATGACATTAAGAGATTTATTGTTAATAGCTTTGCAAGCGTACAATATGAGAATATTTCAGTCGTATTGTCAAA
ACGAAGAGATATTATTGAACAAGCACCAACATATGAAATTAACGAACCTATTTTTGCTTATGATAAGACTATGCCGGTTT
CTATCTTACTTGCATTAATGTCCATTGCGACTTGCTGGCTGTTATGGAAGTACAGGGCTATTATAACTAATTTAATCAGG
TTAAAAAATAAGTAG

Protein sequence :
MKYISLFLFILLLCGCKQQELLNHLDQQQANDVLAVLQRHNINAEKKDQGKTGFSIYVEPTDFASAVDWLKIYNLPGKPD
IQISQMFPADALVSSPRAEKARLYSAIEQRLEQSLKIMDGIVSSRVHVSYDVDTGDSGKTALPIHISVLAVYEKDINPEI
KINDIKRFIVNSFASVQYENISVVLSKRRDIIEQAPTYEINEPIFAYDKTMPVSILLALMSIATCWLLWKYRAIITNLIR
LKNK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ECs3716 NP_311743.1 EprK Not tested LIM Protein 4e-104 97
eprK AAZ31284.1 EprK Virulence ETT2 Protein 1e-102 95
prgK YP_217790.1 cell invasion protein Virulence SPI-1 Protein 8e-58 56
prgK NP_461792.1 needle complex inner membrane lipoprotein Virulence SPI-1 Protein 8e-58 56
prgK AAS66872.1 PrgK Virulence SSR-2 Protein 3e-53 56
prgK NP_457265.1 pathogenicity 1 island effector protein Virulence SPI-1 Protein 1e-58 55
prgK NP_806474.1 pathogenicity island 1 effector protein Virulence SPI-1 Protein 1e-58 55

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
eprK YP_002413872.1 putative type III secretion system lipoprotein EprK VFG0533 Protein 4e-58 56
eprK YP_002413872.1 putative type III secretion system lipoprotein EprK VFG0998 Protein 7e-44 45
eprK YP_002413872.1 putative type III secretion system lipoprotein EprK VFG1787 Protein 2e-38 43