Gene Information

Name : nrdE (ECUMN_3001)
Accession : YP_002413694.1
Strain : Escherichia coli UMN026
Genome accession: NC_011751
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit alpha
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : 1.17.4.1
Position : 3106645 - 3108789 bp
Length : 2145 bp
Strand : +
Note : Catalyzes the rate-limiting step in dNTP synthesis

DNA sequence :
TTGGCAACGACAACCGTAGAACGCCTGACGCAGGAAACGATGGATTACCACGCGCTGAATGCGATGCTTAACCTTTACGA
TAGCGCAGGTCGCATTCAGTTCGATAAAGATCGCCAGGCCGTTGACGCCTTTATGGCGACACATGTGCGTCCGAACAGTG
TGACCTTCAGTAGCCAGCAGCAGCGCCTGAACTGGCTGGTCAACGAAGGTTACTATGATGAAAACGTCCTCAACCGCTAC
TCTCGCGATTTTGTCATTACGCTGTTTGCCCACGCGCACGCCAGCGGTTTTCGTTTCCAGACATTCCTCGGAGCATGGAA
GTTTTACACCAGCTATACGTTGAAGACATTCGACGGTAAGCGTTATCTGGAAGATTTTGCCGATCGAGTCACGATGGTGG
CGCTGACGCTGGCACAAGGCGATGAAACTCTGGCGACGCAACTGACCGATGAGATGCTGTCAGGACGCTTTCAGCCAGCC
ACGCCAACATTCCTCAACTGCGGTAAGCAGCAGCGCGGCGAACTGGTTTCCTGTTTTTTGCTGCGTATTGAAGACAATAT
GGAGTCGATTGGTCGGGCGGTAAATTCCGCACTGCAACTGTCGAAACGCGGCGGCGGCGTAGCATTTTTGCTGTCGAATC
TGCGAGAAGCGGGCGCGCCAATTAAACGTATTGAAAATCAATCATCTGGCGTGATTCCGGTGATGAAAATGCTGGAAGAC
GCATTTTCCTATGCCAACCAGCTCGGCGCGCGTCAGGGTGCTGGCGCAGTCTATTTACATGCCCATCATCCCGATATTCT
GCGTTTTCTCGATACGAAACGGGAAAATGCCGACGAGAAAATCCGCATTAAAACACTGTCGCTGGGCGTGGTGATCCCGG
ATATCACTTTCCATCTGGCAAAAGAGAATGCGCAGATGGCACTGTTTTCGCCTTATGACGTTGAGCGGGTTTATGGCAAG
CCGTTTGCTGATATCGCCATCAGTGAACACTATGCCGAACTGGTTGCCAATGAACGCATCCGCAAAAAATACCTCAACGC
CCGTGATTTCTTCCAGCGACTGGCAGAAATCCAGTTTGAGTCCGGCTATCCCTACATCATGTATGAAGACACGGTTAACC
GTGCTAACCCTATCGCCGGGCGCATAAATATGAGCAATCTCTGCTCAGAAATTTTGCAGGTTAACAGCGCCTCAGAGTAT
GACGAGAATCTCGACTATGCCCGCACAGGCCATGATATTTCCTGCAATTTAGGTTCGTTGAATATTGCCCACACCATGGA
TTCCCCCGACTTTGCCCGCACGGTAGAGACTGCCGTGCGCGGTTTAACGGCGGTGTCAGATATGAGTCATATCCGCAGCG
TGCCGTCCATCGAAGCCGGAAATGCCGCCTCACACGCCATCGGACTGGGGCAGATGAATTTACACGGCTATCTGGCGCGA
GAAGGCATCGCTTATGGTTCGCCGGAAGCACTGGATTTCACCAATCTCTATTTCTATACCATCACCTGGCACGCACTGCG
TACCTCGATGTTGCTGGCGCGCGAACGCGGTGAAACCTTCGCCGGGTTCAAACAGTCACGCTATGCCAGTGGTGAATATT
TTAGCCAATATCTGCAAGGGAACTGGCAGCCGAAAACGGCGAAAGTTGGCGAACTGTTTACCCGTAGCGGTATTACGTTA
CCTACCCGTGAGATGTGGGCGCAGCTGCGCGACGACGTGATGCGCTACGGCATTTACAACCAGAATCTTCAGGCGGTGCC
GCCCACCGGTTCTATCTCTTATATCAACCATGCTACGTCGAGTATTCATCCAATTGTGGCGAAAGTAGAGATACGCAAAG
AGGGCAAAACAGGGCGCGTTTACTACCCTGCCCCGTTTATGACTAACGAAAATCTGGCGCTGTATCAGGACGCTTACGAA
ATCGGCGCAGAAAAGATCATCGACACCTACGCGGAAGCGACTCGCCATGTCGATCAGGGGCTGTCGCTGACGCTGTTTTT
CCCCGATACCGCCACCACTCGCGATATCAACAAAGCGCAGATTTACGCCTGGCGCAAGGGTATCAAAACGCTCTACTACA
TCCGCCTGCGTCAGATGGCGCTGGAAGGCACTGAAATTGAAGGCTGCGTCTCCTGTGCACTTTAA

Protein sequence :
MATTTVERLTQETMDYHALNAMLNLYDSAGRIQFDKDRQAVDAFMATHVRPNSVTFSSQQQRLNWLVNEGYYDENVLNRY
SRDFVITLFAHAHASGFRFQTFLGAWKFYTSYTLKTFDGKRYLEDFADRVTMVALTLAQGDETLATQLTDEMLSGRFQPA
TPTFLNCGKQQRGELVSCFLLRIEDNMESIGRAVNSALQLSKRGGGVAFLLSNLREAGAPIKRIENQSSGVIPVMKMLED
AFSYANQLGARQGAGAVYLHAHHPDILRFLDTKRENADEKIRIKTLSLGVVIPDITFHLAKENAQMALFSPYDVERVYGK
PFADIAISEHYAELVANERIRKKYLNARDFFQRLAEIQFESGYPYIMYEDTVNRANPIAGRINMSNLCSEILQVNSASEY
DENLDYARTGHDISCNLGSLNIAHTMDSPDFARTVETAVRGLTAVSDMSHIRSVPSIEAGNAASHAIGLGQMNLHGYLAR
EGIAYGSPEALDFTNLYFYTITWHALRTSMLLARERGETFAGFKQSRYASGEYFSQYLQGNWQPKTAKVGELFTRSGITL
PTREMWAQLRDDVMRYGIYNQNLQAVPPTGSISYINHATSSIHPIVAKVEIRKEGKTGRVYYPAPFMTNENLALYQDAYE
IGAEKIIDTYAEATRHVDQGLSLTLFFPDTATTRDINKAQIYAWRKGIKTLYYIRLRQMALEGTEIEGCVSCAL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 0.0 72