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Name : irp (ECUMN_2277) Accession : YP_002412995.1 Strain : Escherichia coli UMN026 Genome accession: NC_011751 Putative virulence/resistance : Virulence Product : salicyl-AMP ligase YbtE Function : - COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism COG ID : COG1021 EC number : - Position : 2304148 - 2305725 bp Length : 1578 bp Strand : + Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9818149, 11927258, 9709002; Product type e : enzyme DNA sequence : ATGAATTCTTCCTTTGAATCTCTGATTGAACAGTATCCCTTACCCATTGCCGAACAGTTGCGCCACTGGGCGGCCCGTTA TGCCTCGCGAATTGCCGTCGTTGATGCAAAGGGGTCGTTAACCTACAGCGCGCTTGATGCACAAGTTGACGAACTTGCCG CAGGTCTGTCATCACTGGGTTTGCGTTCGGGGGAGCATGTAATTGTGCAGCTTCCCAACGACAACGCGTTTGTTACCCTG CTGTTCGCCTTGTTAAGACTGGGCGTTATCCCCGTGCTGGCGATGCCCTCGCAACGGGCGCTGGATATCGACGCGCTGAT TGAGCTGGCGCAACCCGTCGCTTACGTTATTCACGGGGAAAACCACGCAGAGCTGGCCCGACAGATGGCGCACAAACACG CCTGCTTGCGTCATGTTCTGGTCGCTGGAGAGACCGTGAGCGACGATTTTACGCCGCTCTTCTCCCTTCACGGTGAGCGA CAGGCATGGCCGCAGCCTGATGTTTCCGCCACCGCGTTGTTGTTGCTCTCAGGCGGCACAACCGGCACGCCCAAACTCAT CCCGCGCCGACATGCCGACTATAGCTATAACTTCAGCGCTTCTGCTGAACTGTGCGGCATCAGCCAACAGAGCGTGTATC TCGCCGTCCTCCCGGTGGCGCATAACTTTCCGCTGGCCTGCCCCGGTATTCTGGGAACGCTTGCCTGCGGCGGAAAAGTG GTGCTGACCGACAGCGCCAGCTGTGATGAGGTGATGCCTTTAATCGCGCAGGAAAGAGTGACTCACGTCGCCCTGGTTCC GGCGCTGGCGCAATTATGGGTGCAGGCCAGGGAGTGGGAAGACAGCGACCTTTCGTCGCTGCGCGTCATTCAGGCAGGCG GCGCCCGGCTCGACCCGACGCTTGCTGAGCAGGTTATCGCCACCTTTGACTGTACCCTGCAACAGGTTTTCGGTATGGCG GAAGGCCTGCTCTGTTTTACCCGGCTGGACGATCCGCATGCCACCATTCTCCACAGCCAGGGGCGCCCGTTGTCCCCTCT GGATGAAATCCGCATCGTTGATCAAGACGAGAACGACGTCGCGCCGGGCGAAACCGGGCAATTGTTAACGCGCGGCCCTT ATACCATTTCGGGCTATTACCGCGCCCCTGCCCACAACGCGCAGGCCTTTACCGCGCAAGGGTTTTACCGCACAGGCGAC AATGTCAGGCTGGATGAGGTGGGGAACCTGCACGTTGAGGGACGCATAAAAGAGCAGATCAACCGCGCCGGAGAAAAAAT AGCCGCGGCTGAAGTGGAATCGGCACTGCTGCGTTTAGCGGAAGTGCAAGATTGCGCGGTGGTCGCCGCGCCGGACACGC TGCTTGGCGAGCGGATTTGCGCGTTTATCATCGCGCAGCAGGTGCCAACTGACTATCAGCAGTTGCGTCAACAACTGACC CGTATGGGGCTCAGCGCGTGGAAAATTCCTGACCAAATCGAGTTTCTGGACCACTGGCCGCTCACCGCCGTCGGCAAGAT AGACAAAAAACGCCTGACGGCTCTCGCCGTCGACCGTTATCGCCATTCTGCCCAATAA Protein sequence : MNSSFESLIEQYPLPIAEQLRHWAARYASRIAVVDAKGSLTYSALDAQVDELAAGLSSLGLRSGEHVIVQLPNDNAFVTL LFALLRLGVIPVLAMPSQRALDIDALIELAQPVAYVIHGENHAELARQMAHKHACLRHVLVAGETVSDDFTPLFSLHGER QAWPQPDVSATALLLLSGGTTGTPKLIPRRHADYSYNFSASAELCGISQQSVYLAVLPVAHNFPLACPGILGTLACGGKV VLTDSASCDEVMPLIAQERVTHVALVPALAQLWVQAREWEDSDLSSLRVIQAGGARLDPTLAEQVIATFDCTLQQVFGMA EGLLCFTRLDDPHATILHSQGRPLSPLDEIRIVDQDENDVAPGETGQLLTRGPYTISGYYRAPAHNAQAFTAQGFYRTGD NVRLDEVGNLHVEGRIKEQINRAGEKIAAAEVESALLRLAEVQDCAVVAAPDTLLGERICAFIIAQQVPTDYQQLRQQLT RMGLSAWKIPDQIEFLDHWPLTAVGKIDKKRLTALAVDRYRHSAQ |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| irp5 | YP_002346898.1 | yersiniabactin siderophore biosynthetic protein | Virulence | HPI | Protein | 0.0 | 100 |
| ybtE | NP_669710.1 | salicyl-AMP ligase | Virulence | HPI | Protein | 0.0 | 100 |
| ybtE | NP_993003.1 | yersiniabactin siderophore biosynthetic protein | Virulence | HPI | Protein | 0.0 | 100 |
| ybtE | YP_070120.1 | yersiniabactin siderophore biosynthetic protein | Virulence | HPI | Protein | 0.0 | 100 |
| ybtE | CAA21394.1 | - | Virulence | HPI | Protein | 0.0 | 100 |
| ybtE | AAA93464.1 | yersiniabactin 2,3-dihydoxybenzoate-AMP ligase | Virulence | HPI | Protein | 0.0 | 100 |
| ybtE | YP_853079.1 | yersiniabactin siderophore biosynthetic protein | Virulence | PAI IV APEC-O1 | Protein | 0.0 | 99 |
| irp5 | CAA73130.1 | Irp5 protein | Virulence | HPI | Protein | 0.0 | 98 |
| irp5 | YP_001006819.1 | yersiniabactin siderophore biosynthetic protein | Virulence | HPI | Protein | 0.0 | 98 |
| irp2E | YP_005163485.1 | siderophore biosynthetic protein | Virulence | Not named | Protein | 4e-75 | 42 |
| irp2E | YP_005134497.1 | siderophore biosynthetic protein | Virulence | Not named | Protein | 4e-75 | 42 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| irp | YP_002412995.1 | salicyl-AMP ligase YbtE | VFG0168 | Protein | 8e-107 | 51 |
| irp | YP_002412995.1 | salicyl-AMP ligase YbtE | VFG1817 | Protein | 3e-88 | 44 |
| irp | YP_002412995.1 | salicyl-AMP ligase YbtE | VFG0932 | Protein | 4e-80 | 43 |
