Gene Information

Name : yedW (ECUMN_2260)
Accession : YP_002412979.1
Strain : Escherichia coli UMN026
Genome accession: NC_011751
Putative virulence/resistance : Virulence
Product : transcriptional regulatory protein YedW
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 2271730 - 2272401 bp
Length : 672 bp
Strand : -
Note : induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistanc

DNA sequence : 
ATGAAGATTTTACTTATTGAAGATAATCAAAGGACCCAGGAGTGGGTAACGCAGGGGCTTTCCGAAGCGGGTTATGTCAT
TGATGCCGTTTCTGATGGCAGAGATGGGCTTTATCTTGCGCTGAAGGATGATTATGCATTGATCATTCTGGATATTATGC
TTCCGGGTATGGATGGCTGGCAGATCTTACAAACGTTAAGAACAGCAAAGCAAACCCCTGTTATTTGCCTTACTGCAAGG
GATTCTGTCGATGACAGAGTCAGAGGGCTGGACAGTGGAGCAAATGATTATCTGGTAAAACCTTTTTCATTTTCTGAGTT
GCTGGCAAGGGTTCGGGCACAATTAAGGCAACATCATGCTTTGAATTCAACATTAGAAATCAGTGGCTTAAGAATGGACT
CTGTTAGTCAAAGTGTGAGCAGGGACAATATCAGTATTACACTGACGCGCAAGGAGTTTCAGTTACTTTGGCTACTGGCC
TCCAGAGCTGGCGAAATTATACCCAGAACGGTTATTGCGAGTGAAATTTGGGGAATCAACTTTGATAGTGATACCAATAC
GGTGGACGTCGCCATTCGCAGGCTCCGCGCAAAAGTTGATGATCCTTTTCCTGAAAAGCTAATCGCCACAATCCGGGGGA
TGGGCTATTCATTCGTAGCGGTAAAAAAATAA

Protein sequence : 
MKILLIEDNQRTQEWVTQGLSEAGYVIDAVSDGRDGLYLALKDDYALIILDIMLPGMDGWQILQTLRTAKQTPVICLTAR
DSVDDRVRGLDSGANDYLVKPFSFSELLARVRAQLRQHHALNSTLEISGLRMDSVSQSVSRDNISITLTRKEFQLLWLLA
SRAGEIIPRTVIASEIWGINFDSDTNTVDVAIRRLRAKVDDPFPEKLIATIRGMGYSFVAVKK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 1e-80 77
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 5e-80 76

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
yedW YP_002412979.1 transcriptional regulatory protein YedW BAC0125 Protein 8e-59 57
yedW YP_002412979.1 transcriptional regulatory protein YedW BAC0197 Protein 4e-56 56
yedW YP_002412979.1 transcriptional regulatory protein YedW BAC0083 Protein 4e-54 54
yedW YP_002412979.1 transcriptional regulatory protein YedW BAC0308 Protein 3e-52 53
yedW YP_002412979.1 transcriptional regulatory protein YedW BAC0111 Protein 9e-56 52
yedW YP_002412979.1 transcriptional regulatory protein YedW BAC0638 Protein 6e-49 52
yedW YP_002412979.1 transcriptional regulatory protein YedW BAC0347 Protein 3e-50 49
yedW YP_002412979.1 transcriptional regulatory protein YedW NC_007793.3914065.p0 Protein 2e-38 42
yedW YP_002412979.1 transcriptional regulatory protein YedW NC_002758.1121390.p0 Protein 2e-38 42
yedW YP_002412979.1 transcriptional regulatory protein YedW NC_010079.5776364.p0 Protein 2e-38 42
yedW YP_002412979.1 transcriptional regulatory protein YedW NC_002952.2859858.p0 Protein 2e-38 42
yedW YP_002412979.1 transcriptional regulatory protein YedW NC_007622.3794948.p0 Protein 2e-38 42
yedW YP_002412979.1 transcriptional regulatory protein YedW AE015929.1.gene1106. Protein 2e-33 42
yedW YP_002412979.1 transcriptional regulatory protein YedW NC_003923.1003417.p0 Protein 2e-38 42
yedW YP_002412979.1 transcriptional regulatory protein YedW NC_013450.8614146.p0 Protein 2e-38 42
yedW YP_002412979.1 transcriptional regulatory protein YedW NC_002951.3238224.p0 Protein 2e-38 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
yedW YP_002412979.1 transcriptional regulatory protein YedW VFG0596 Protein 5e-81 77