Gene Information

Name : ECUMN_0219 (ECUMN_0219)
Accession : YP_002410990.1
Strain : Escherichia coli UMN026
Genome accession: NC_011751
Putative virulence/resistance : Virulence
Product : putative ATP-dependent Clp proteinase Aec27 ATP-binding chain, with chaperone activity
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 249130 - 251862 bp
Length : 2733 bp
Strand : -
Note : Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor

DNA sequence :
ATGATCCAGATTGATTTAGCCACGCTGGTAAAGCGGCTTAACCCCTTTGCAAAACAGGCGCTGGAAATGGCTGCCTCGGA
GTGTATGAGCCAGCAGGCCAGTGAGATCACCGTTGCCCATATGCTGTTGCAGATGCTGGTTATCCCGCGCAGCGACGTAA
GGGTGATTGCCGAACGCACAGGCATCAGTGCGGAGGATTTACGCCAGGCGCTGACCGTGGAGAGTTATCCCGGCGGACGT
TCCGCCGAAGGCTATCCCAGCTTCTCCCCGATGCTGATCGAATGGCTCAAGGAGTCATGGCTGCTGGCCTCAGCCCAGAT
GCAGCACAGCGAACTGCGCAGCGGCGTCCTGCTGCTTACTCTGCTGCATTCACCGCTGCGCTATATTCCACCCGCTGCTG
CCCGTCTGCTGACGGCCATAAACCGTGACCAGTTACAGCAGGATTTCACCGCATGGACAAAAGAATCCGCCGAATCCGTG
GATCTGGCTGGTGGGCAAGCGTTCCGTGCAACAGAAACCGGCGACACCCTGCTTGCCCGCTATGCCAAAAATATGACCGA
AGACGCCCGTAACGGAAAACTCGATCCGGTACTGTGCCGCGACCACGAAATCGATTTGATGATCGACATTCTCTGCCGCC
GTCGTAAAAATAACCCGGTGGTAGTGGGCGAAGCGGGCGTGGGCAAAAGCGCACTGATTGAAGGGCTGGCGCTGCGCATC
GTGGCAGGCCAGGTGCCGGACAAGCTGAAAAACACCGATATCATGACCCTTGACCTGGGCGCATTGCAGGCCGGAGCGTC
GGTGAAGGGCGAATTCGAAAAACGTTTCAAAGGGCTGATGGCGGAGGTCATTTCCTCCCCGGTGCCGATCATTCTGTTTA
TCGACGAAGCGCATACCCTGATTGGCGCGGGCAACCAGCAGGGCGGGCTGGATATCTCCAACCTGCTCAAACCGGCGCTG
GCGCGTGGCGAACTGAAAACCATCGCCGCCACAACCTGGAGCGAATACAAAAAATACTTCGAAAAAGACGCTGCCTTATC
GCGCCGCTTCCAGTTAGTTAAGGTCAGCGAACCTAACGCTGCCGAAGCGACGATTATTCTGCGTGGCCTGTCGGCGGTCT
ATGAACAGTCTCACGGTGTGCTGATTGACGATGAGGCCTTACAAGCCGCAGCAACACTGAGCGAGCGTTATCTCTCCGGA
CGTCAGTTGCCGGACAAAGCGATTGATGTGCTGGACACCGCCTGCGCCCGCGTGGCAATCAACCTTTCTTCGCCGCCGAA
ACAGATTTCGGCGCTGGCCACGTTAAGCCAGCAGCAGGAGACGGAAATCCGCCAGCTTGAGCGCGAAAGGCGTATCGGGC
TGCGTACCGATACCGCCCGGATGACGGAAGTGCTGGTGCAGTACGATGAAACACTGACGGCGCTGGATGAACTGGAAGCC
GCCTGGCACCAGCAACAGGCGCTGGTACAGGAGATTATTACGCTACGCCAGCAGTTACTGGGCGTTGCAGAGGACACAGA
TGCCGTAGTGGATACGCCGCCAGAGTCAGAACAGGATAATACTGGTGCCATACCGGCTGATGAAGCTGGCAGCGTACAGC
CGGAAGAGACCGCTGAAACAGTTTCCCCGGTACAGCGGCTGGCACAGCTTACTGCCGAACTGGACGCCCTGCATAACGAT
CGGTTGCTGGTCTCTCCGCATGTCGATAAAAAACAGATTGCGGCGGTAATTGCCGAATGGACTGGTGTTCCGCTTAACCG
CCTGTCGCAGAATGAAATGTCGGTCATCACCGACCTGCCGAAGTGGCTTGGTGACACCATCAAAGGCCAGGACCTGGCGA
TTGCCAGCCTGCATAAACACCTGCTGACCGCACGCGCCGACCTGCGCCGTCCGGGACGCCCGCTTGGCGCGTTTCTGCTG
GCTGGTCCCAGTGGCGTGGGTAAAACCGAAACCGTCCTGCAACTGGCAGAGCTGCTCTACGGCGGTCGCCAGTACCTGAC
CACCATCAATATGTCCGAGTTCCAGGAGAAGCACACCGTCTCGCGGCTGATTGGTTCCCCTCCGGGCTATGTCGGCTATG
GCGAAGGCGGCGTGCTGACTGAGGCCATCCGCCAGAAACCCTACTCGGTGGTACTTCTCGATGAAGTGGAAAAAGCGCAC
CCGGATGTGCTCAACCTGTTCTACCAGGCGTTTGACAAGGGCGAGATGGCGGACGGCGAGGGCCGCCTGATTGACTGTAA
AAACATCGTCTTCTTCCTCACCTCCAACCTCGGCTATCAGGTGATTGTCGAACACGCCGATGACCCGGAAACCATGCAGG
AAGCCCTGTATCCGGTGCTGGCAGACTTCTTTAAACCCGCCCTGCTGGCGCGTATGGAAGTGGTGCCATACCTGCCGCTG
TCGAAAGCGACGCTCGCTACCATTATTGCCGGGAAACTGGCCCGCCTGGATAACGTGCTGCGCAGCCGCTTTGGTGCGGA
CGTGATTATTGAACCGGAAGTGACGGACGAAATCATGAGCCGCGTCACCCGCGCGGAAAACGGCGCGAGGATGCTCGAAT
CGGTCATTGACGGCGACATGCTGCCGCCGCTCTCGCTGCTGCTGTTGCAGAAAATGGCGGCTAACACGGCGATTGCCCGG
ATTCGCCTGTCGGTGGCAGACGGTGCATTCACAGCAGACGTGGAAGATGTTCTGAACGACGAGTCCGTCACAGAGGATGA
AACGGTTTTATGA

Protein sequence :
MIQIDLATLVKRLNPFAKQALEMAASECMSQQASEITVAHMLLQMLVIPRSDVRVIAERTGISAEDLRQALTVESYPGGR
SAEGYPSFSPMLIEWLKESWLLASAQMQHSELRSGVLLLTLLHSPLRYIPPAAARLLTAINRDQLQQDFTAWTKESAESV
DLAGGQAFRATETGDTLLARYAKNMTEDARNGKLDPVLCRDHEIDLMIDILCRRRKNNPVVVGEAGVGKSALIEGLALRI
VAGQVPDKLKNTDIMTLDLGALQAGASVKGEFEKRFKGLMAEVISSPVPIILFIDEAHTLIGAGNQQGGLDISNLLKPAL
ARGELKTIAATTWSEYKKYFEKDAALSRRFQLVKVSEPNAAEATIILRGLSAVYEQSHGVLIDDEALQAAATLSERYLSG
RQLPDKAIDVLDTACARVAINLSSPPKQISALATLSQQQETEIRQLERERRIGLRTDTARMTEVLVQYDETLTALDELEA
AWHQQQALVQEIITLRQQLLGVAEDTDAVVDTPPESEQDNTGAIPADEAGSVQPEETAETVSPVQRLAQLTAELDALHND
RLLVSPHVDKKQIAAVIAEWTGVPLNRLSQNEMSVITDLPKWLGDTIKGQDLAIASLHKHLLTARADLRRPGRPLGAFLL
AGPSGVGKTETVLQLAELLYGGRQYLTTINMSEFQEKHTVSRLIGSPPGYVGYGEGGVLTEAIRQKPYSVVLLDEVEKAH
PDVLNLFYQAFDKGEMADGEGRLIDCKNIVFFLTSNLGYQVIVEHADDPETMQEALYPVLADFFKPALLARMEVVPYLPL
SKATLATIIAGKLARLDNVLRSRFGADVIIEPEVTDEIMSRVTRAENGARMLESVIDGDMLPPLSLLLLQKMAANTAIAR
IRLSVADGAFTADVEDVLNDESVTEDETVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 0.0 95
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 0.0 95
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 3e-126 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ECUMN_0219 YP_002410990.1 putative ATP-dependent Clp proteinase Aec27 ATP-binding chain, with chaperone activity VFG2084 Protein 0.0 57
ECUMN_0219 YP_002410990.1 putative ATP-dependent Clp proteinase Aec27 ATP-binding chain, with chaperone activity VFG2076 Protein 2e-145 43