Gene Information

Name : cvrA (ECUMN_1482)
Accession : YP_002412227.1
Strain : Escherichia coli UMN026
Genome accession: NC_011751
Putative virulence/resistance : Unknown
Product : potassium/proton antiporter
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG3263
EC number : -
Position : 1488477 - 1490213 bp
Length : 1737 bp
Strand : -
Note : the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli

DNA sequence :
TTGGATGCCACAACAATAATTAGCCTTTTCATCTTAGGATCCATCCTTGTCACCAGCAGTATATTACTTAGTTCATTTTC
TTCCCGTCTTGGCATTCCTATTCTGGTTATTTTTCTGGCGATCGGCATGCTGGCGGGAGTCGATGGCGTCGGCGGTATCC
CGTTTGATAATTACCCCTTCGCCTACATGGTAAGTAACCTGGCGCTGGCGATTATTTTGCTCGACGGCGGGATGCGCACT
CAGGCCAGTTCCTTTCGTGTGGCGTTAGGACCGGCGCTGTCGCTGGCGACGCTGGGCGTGCTTATCACCTCTGGTTTAAC
CGGCATGATGGCGGCGTGGCTGTTTAATCTTGATTTGATTGAAGGCTTATTAATCGGCGCTATCGTCGGCTCCACCGATG
CTGCGGCGGTATTTTCTCTGCTGGGTGGTAAGGGGCTTAACGAACGCGTTGGCTCGACGCTGGAAATTGAATCCGGCAGT
AATGATCCAATGGCGGTCTTTCTGACGATTACCCTGATTGCGATGATCCAGCAGCATGAAAGCAGTGTCAGCTGGATGTT
CGTGGTCGATATTTTGCAGCAATTTGGCCTCGGGATTGTCATCGGTCTTGGCGGTGGTTATTTACTGCTGCAAATGATTA
ATCGCATCGCCCTGCCCGCCGGTTTATATCCATTGCTGGCATTAAGCGGCGGTATTTTAATTTTTGCTTTAACCACGGCG
CTGGAAGGCAGCGGTATTCTGGCTGTTTATCTGTGCGGTTTTCTGCTGGGTAATCGGCCGATTCGCAACCGCTACGGCAT
CCTGCAAAATTTCGACGGCCTCGCCTGGCTGGCGCAAATCGCCATGTTCCTGGTGCTGGGGCTGTTGGTTAACCCAAGCG
ATCTGCTGCCTATTGCCATTCCGGCGCTCATTTTGTCCGCATGGATGATTTTCTTCGCCCGTCCTCTTTCGGTATTTGCC
GGATTGCTACCGTTCCGTGGTTTTAATCTGCGTGAGCGCGTGTTTATCAGCTGGGTGGGATTACGCGGCGCGGTGCCAAT
CATCCTGGCCGTGTTCCCGATGATGGCGGGGCTGGAGAATGCGCGACTGTTCTTTAATGTCGCCTTCTTTGTGGTTCTGG
TTTCACTGCTCTTGCAGGGAACATCACTCTCGTGGGCGGCGAAAAAAGCCAAAGTGGTCGTTCCGCCAGTGGGACGTCCG
GTGTCACGCGTTGGTCTGGATATTCATCCGGAAAATCCGTGGGAGCAGTTTGTTTATCAGTTGAGTGCCGATAAATGGTG
CGTGGGCGCGGCACTGCGTGATCTGCATATGCCAAAAGAGACGCGTATTGCGGCACTGTTTCGTGATAACCAGTTGCTTC
ATCCTACCGGCAGCACCCGACTGCGCGAAGGCGATGTGTTGTGTGTAATTGGTCGGGAACGCGATCTCCCGGCGCTCGGT
AAACTGTTCAGCCAGTCGCCGCCGGTCGCGCTGGATCAACGCTTCTTTGGTGACTTCATTCTCGAAGCCAGCGCCAAATA
TGCAGATGTGGCGCTGATATATGGCCTGGAAGACGGGCGAGAATATCGTGATAAGCAACAAACGCTGGGTGAAATTGTCC
AGCAGTTGTTAGGCGCGGCACCGGTTGTCGGTGACCAGGTAGAGTTTGCCGGAATGATCTGGACGGTGGCCGAGAAAGAA
GATAATGAAGTGTTGAAGATTGGCGTACGGGTGGCAGAAGAGGAAGCTGAATCTTAA

Protein sequence :
MDATTIISLFILGSILVTSSILLSSFSSRLGIPILVIFLAIGMLAGVDGVGGIPFDNYPFAYMVSNLALAIILLDGGMRT
QASSFRVALGPALSLATLGVLITSGLTGMMAAWLFNLDLIEGLLIGAIVGSTDAAAVFSLLGGKGLNERVGSTLEIESGS
NDPMAVFLTITLIAMIQQHESSVSWMFVVDILQQFGLGIVIGLGGGYLLLQMINRIALPAGLYPLLALSGGILIFALTTA
LEGSGILAVYLCGFLLGNRPIRNRYGILQNFDGLAWLAQIAMFLVLGLLVNPSDLLPIAIPALILSAWMIFFARPLSVFA
GLLPFRGFNLRERVFISWVGLRGAVPIILAVFPMMAGLENARLFFNVAFFVVLVSLLLQGTSLSWAAKKAKVVVPPVGRP
VSRVGLDIHPENPWEQFVYQLSADKWCVGAALRDLHMPKETRIAALFRDNQLLHPTGSTRLREGDVLCVIGRERDLPALG
KLFSQSPPVALDQRFFGDFILEASAKYADVALIYGLEDGREYRDKQQTLGEIVQQLLGAAPVVGDQVEFAGMIWTVAEKE
DNEVLKIGVRVAEEEAES

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
f536 AAC61706.1 F536 Not tested PAI I CFT073 Protein 0.0 99
unnamed AAB61290.1 unknown Not tested PAI I CFT073 Protein 0.0 99