Gene Information

Name : umuC (ECUMN_1473)
Accession : YP_002412218.1
Strain : Escherichia coli UMN026
Genome accession: NC_011751
Putative virulence/resistance : Unknown
Product : DNA polymerase V subunit UmuC
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0389
EC number : -
Position : 1477461 - 1478729 bp
Length : 1269 bp
Strand : +
Note : binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization

DNA sequence :
ATGTTTGCCCTCTGTGATGTAAACGCGTTTTATGCCAGCTGTGAGACGGTGTTTCGCCCTGATTTATGGGGTAAACCAGT
GGTTGTGCTATCGAATAATGACGGTTGCGTTATCGCCCGAAACGCTGAGGCAAAGGCGCTGGGTGTTAAAATGGGCGATC
CCTGGTTCAAACAAAAAGATCTGTTTCGTCGCTGTGGCGTGGTTTGCTTTAGCAGCAATTATGAGCTTTACGCAGACATG
AGCAATCGGGTGATGTCGACGCTGGAAGAGCTATCGCCCCGCGTCGAGATTTACAGTATTGATGAGGCATTCTGCGATCT
GACCGGTGTGCGTAATTGTCGCGATCTGACTGATTTGGGCAGAGAAATTCGCGCAACGGTACTACAACGTACCCATCTTA
CTGTTGGTGTGGGGATCGCCCAGACCAAAACGCTGGCTAAGCTTGCCAATCATGCGGCAAAAAAATGGCAGCGGCAGACG
GGTGGGGTGGTGGATTTATCAAATCTGGAACGCCAGCGTAAATTAATGTCTGCTCTCCCCGTGGATGAAGTCTGGGGGAT
TGGACGGCGGATCAGCAAAAAACTGGACGCGATGGGGATCAAAACCGTTCTCGATTTGGCGGATACAGATATCCGGTTTA
TCCGTAAACATTTTAATGTCGTGCTCGAAAGAACGGTGCGTGAACTGCGCGGTGAACCCTGTTTGCAACTGGAAGAGTTT
GCACCGACAAAGCAGGAAATTATCTGTTCCCGTTCGTTTGGTGAACGCATCACGGATTATACGTCGATGCGGCAGGCCAT
TTGTAGTTACGCTGCCCGGGCGGCGGAAAAACTTCGCAGTGAGCATCAATATTGTCGGTTTATTTCCACGTTTATTAAGA
CGTCACCATTTGCGCTCAATGAACCTTATTACGGCAATAGCGCGTCGGTAAAACTGCTGACACCCACTCAGGACAGCAGG
GATATCATTAACGCCGCTACGCGATCTCTGGATGCCATCTGGCAAGCGGGCCATCGCTACCAAAAAGCGGGCGTGATGCT
GGGAGATTTCTTCAGTCAGGGAGTCGCGCAGCTCAATTTATTCGATGACAACGCACCGCGCCCCGGGAGTGAGCAATTGA
TGGCGGTAATGGATACGCTAAATGCTAAAGAGGGCAGAGGAACACTCTATTTTGCTGGGCAGGGGATCCAGCAACAATGG
CAGATGAAGCGTGCCATGCTTTCACCACGTTATACAACGCGAAGTTCTGATTTACTGCGGGTCAAATAA

Protein sequence :
MFALCDVNAFYASCETVFRPDLWGKPVVVLSNNDGCVIARNAEAKALGVKMGDPWFKQKDLFRRCGVVCFSSNYELYADM
SNRVMSTLEELSPRVEIYSIDEAFCDLTGVRNCRDLTDLGREIRATVLQRTHLTVGVGIAQTKTLAKLANHAAKKWQRQT
GGVVDLSNLERQRKLMSALPVDEVWGIGRRISKKLDAMGIKTVLDLADTDIRFIRKHFNVVLERTVRELRGEPCLQLEEF
APTKQEIICSRSFGERITDYTSMRQAICSYAARAAEKLRSEHQYCRFISTFIKTSPFALNEPYYGNSASVKLLTPTQDSR
DIINAATRSLDAIWQAGHRYQKAGVMLGDFFSQGVAQLNLFDDNAPRPGSEQLMAVMDTLNAKEGRGTLYFAGQGIQQQW
QMKRAMLSPRYTTRSSDLLRVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
samB NP_458681.1 UV protection protein Not tested SPI-7 Protein 4e-126 63
umuC NP_807889.1 DNA polymerase V subunit UmuC Not tested SPI-7 Protein 4e-126 63
rulB CAI36137.1 nucleotidyltransferase/DNA polymerase Not tested PPHGI-1 Protein 4e-90 50
unnamed ABR13403.1 DNA-directed DNA polymerase Not tested PAGI-5 Protein 2e-75 49