Gene Information

Name : papC (ECIAI39_4589)
Accession : YP_002410453.1
Strain : Escherichia coli IAI39
Genome accession: NC_011750
Putative virulence/resistance : Virulence
Product : outer membrane usher protein PapC
Function : -
COG functional category : N : Cell motility
COG ID : COG3188
EC number : -
Position : 4787118 - 4789649 bp
Length : 2532 bp
Strand : +
Note : Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2897064, 1357526, 12399496, 2572580, 7909802, 9501230; Product type f : factor

DNA sequence :
GTGAATCTGGTGATGCGTGGAATGAAAGACAGAATACCTTTTGCAGTCAACAATATTACCTGTGTGATATTGTTGTCTCT
GTTTTGTAACGCAGCCAGTGCCGTTGAGTTTAATACAGATGTACTTGACGCGGCGGACAAGAAAAATATTGACTTCACCC
GTTTTTCAGAAGCTGGTTATGTTCTGCCGGGGCAATATCTTCTGGATGTGATTGTTAACGGGCAAAGTATTTCTCCCGCA
TCGTTACAGATTTCATTTGTTGAACCTCAGTCGTCAGGAGATAAGGCAGAAAAAAAATTGCCACAGGCCTGTCTGACATC
AGATATGGTCAGACTGATGGGGTTAACAGCAGAATCTCTGGATAAAGTTGTTTACTGGCATGATGGTCAGTGTGCGGATT
TTCATGGGTTGCCGGGAGTGGATATTCGTCCTGATACCGGAGCGGGCGTATTACGCATCAATATGCCGCAGGCCTGGCTT
GAGTATTCTGATGCCACCTGGCTGCCTCCCTCACGCTGGGACGACGGCATTCCCGGACTGATGCTGGATTATAACCTCAA
CGGGACGGTTTCCCGTAATTATCAGGGAGGAGACTCTCATCAGTTCAGTTATAACGGGACTGTGGGGGGGAATCTGGGGC
CCTGGCGCCTGCGGGCTGACTATCAGGGAAGCCAGGAGCAGAGCCGCTACAACGGGGAAAAAACGACAAACAGAAATTTC
ACATGGAGTCGCTTTTATCTGTTCCGTGCCATTCCACGATGGCGGGCAAACCTGACGCTGGGCGAGAATAATATCAACTC
AGATATATTCCGGTCATGGAGTTATACGGGAGCCAGCCTGGAAAGCGATGACCGGATGCTGCCACCCAGACTGCGAGGCT
ATGCACCGCAGATTACCGGGATTGCGGAGACTAATGCCCGTGTTGTGGTGTCGCAGCAGGGACGGGTGCTGTACGACTCG
ATGGTCCCCGCAGGGCCATTCAGTATTCAGGACCTGGACAGTTCAGTTCGCGGACGTCTTGATGTTGAGGTTATTGAACA
GAACGGACGGAAGAAAACCTTTCAGGTCGATACGGCCTCGGTTCCTTATCTGACGCGTCCGGGACAGGTCCGGTATAAAC
TTGTCTCCGGTCGTTCCCGCGGATACGGGCATGAGACCGAAGGGCCTGTATTTGCGACCGGAGAGGCGTCCTGGGGGCTC
AGTAACCAGTGGTCGCTGTATGGCGGGGCTGTGCTTGCCGGTGATTATAATGCACTGGCAGCCGGTGCCGGCTGGGACCT
GGGTGTGCCGGGGACCCTTTCCGCTGATATCACGCAGTCAGTAGCCCGTATTGAGGGAGAGAGAACGTTTCAGGGAAAAT
CCTGGCGTCTTAGCTACTCCAAACGGTTTGATAATGCGGATGCCGACATTACGTTCGCCGGGTATCGTTTCTCAGAGCGA
AACTATATGACCATGGAGCAGTACCTGAACGCCCGCTACCGTAATGATTACAGCAGTCGGGAAAAAGAGATGTATACCGT
TACGCTGAATAAAAACGTGGCGGACTGGAACACCTCTTTTAACCTGCAGTACAGCCGTCAGACATACTGGGACATACGGA
AAACGGACTATTATACGGTGAGCGTCAACCGCTACTTTAATGTTTTCGGACTGCAGGGAGTGGCGGTTGGATTGTCAGCC
TCAAGGTCTAAATATCTGGGGCGTGATAACGATTCTGCTTACCTGCGTATATCCGTGCCGCTGGGAACGGGGACAGCGAG
CTACAGTGGCAGTATGAGTAATGACCGTTATGTGAATATGGCCGGCTACACTGACACGTTCAATGACGGTCTGGACAGCT
ACAGCCTGAACGCCGGCCTTAACAGTGGCGGTGGACTGACATCGCAACGTCAGATTAATGCCTATTACAGTCATCGTAGT
CCGCTGGCAAATTTGTCCGCGAATATTGCATCCCTGCAGAAAGGATATACGTCTTTCGGCGTCAGTGCTTCCGGTGGGGC
AACAATTACCGGAAAAGGTGCGGCGTTACATGCAGGGGGAATGTCCGGTGGAACACGTCTTCTTGTTGACACGGATGGTG
TGGGAGGTGTACCGGTTGATGGCGGGCAGGTGGTGACAAATCGCTGGGGAACGGGCGTGGTGACTGACATCAGCAGTTAT
TACCGGAATACAACCTCTGTTGACCTGAAGCGCTTACCGGATGATGTGGAAGCAACCCGTTCTGTTGTGGAATCGGCGCT
GACAGAAGGTGCCATTGGTTACCGGAAATTCAGCGTGCTTAAAGGGAAACGTCTGTTTGCAATACTGCGTCTTGCTGATG
GCTCTCAGCCCCCGTTTGGTGCCAGTGTAACCAGTGAAAAAGGCCGGGAGCTGGGCATGGTGGCCGACGAAGGCCTTGCC
TGGCTGAGTGGCGTGACGCCGGGGGAAACCCTGTCGGTAAACTGGGATGGAAAAATACAGTGTCAGGTAAATGTACCGGA
GACAGCAATATCTGACCAGCAGTTATTGCTTCCCTGTACGCCTCAGAAATAA

Protein sequence :
MNLVMRGMKDRIPFAVNNITCVILLSLFCNAASAVEFNTDVLDAADKKNIDFTRFSEAGYVLPGQYLLDVIVNGQSISPA
SLQISFVEPQSSGDKAEKKLPQACLTSDMVRLMGLTAESLDKVVYWHDGQCADFHGLPGVDIRPDTGAGVLRINMPQAWL
EYSDATWLPPSRWDDGIPGLMLDYNLNGTVSRNYQGGDSHQFSYNGTVGGNLGPWRLRADYQGSQEQSRYNGEKTTNRNF
TWSRFYLFRAIPRWRANLTLGENNINSDIFRSWSYTGASLESDDRMLPPRLRGYAPQITGIAETNARVVVSQQGRVLYDS
MVPAGPFSIQDLDSSVRGRLDVEVIEQNGRKKTFQVDTASVPYLTRPGQVRYKLVSGRSRGYGHETEGPVFATGEASWGL
SNQWSLYGGAVLAGDYNALAAGAGWDLGVPGTLSADITQSVARIEGERTFQGKSWRLSYSKRFDNADADITFAGYRFSER
NYMTMEQYLNARYRNDYSSREKEMYTVTLNKNVADWNTSFNLQYSRQTYWDIRKTDYYTVSVNRYFNVFGLQGVAVGLSA
SRSKYLGRDNDSAYLRISVPLGTGTASYSGSMSNDRYVNMAGYTDTFNDGLDSYSLNAGLNSGGGLTSQRQINAYYSHRS
PLANLSANIASLQKGYTSFGVSASGGATITGKGAALHAGGMSGGTRLLVDTDGVGGVPVDGGQVVTNRWGTGVVTDISSY
YRNTTSVDLKRLPDDVEATRSVVESALTEGAIGYRKFSVLKGKRLFAILRLADGSQPPFGASVTSEKGRELGMVADEGLA
WLSGVTPGETLSVNWDGKIQCQVNVPETAISDQQLLLPCTPQK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
prfC CAD42029.1 PrfC protein Virulence PAI II 536 Protein 0.0 100
papC YP_002414015.1 Outer membrane usher protein PapC Not tested Not named Protein 0.0 100
papC YP_854254.1 outer membrane usher protein PapC Virulence PAI I APEC-O1 Protein 0.0 99
papC NP_755465.1 PapC protein Virulence PAI I CFT073 Protein 0.0 99
papC_2 NP_757034.1 PapC protein Virulence PAI II CFT073 Protein 0.0 99
papC AAZ04424.1 outer membrane usher protein Virulence PAI I APEC-O1 Protein 0.0 99
pixC CAE85159.1 PixC protein Not tested PAI V 536 Protein 0.0 72

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
papC YP_002410453.1 outer membrane usher protein PapC VFG1548 Protein 0.0 100
papC YP_002410453.1 outer membrane usher protein PapC VFG0895 Protein 0.0 99
papC YP_002410453.1 outer membrane usher protein PapC VFG0884 Protein 0.0 99