Gene Information

Name : ECIAI39_4190 (ECIAI39_4190)
Accession : YP_002410066.1
Strain : Escherichia coli IAI39
Genome accession: NC_011750
Putative virulence/resistance : Virulence
Product : SHI-2 pathogenicity island protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4363387 - 4364430 bp
Length : 1044 bp
Strand : +
Note : Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10411725; Product type pe : putative enzyme

DNA sequence :
ATGAACGATAGATTATGCTTTGAAGTGCACGATAACAAGGGTTATTTCGTATTTCCGGATACCTGGTTTGGCCCATTGCT
GGGGGAGTTTGAAGAAGTGCTTGATGCATACGACGCTGATGAAATCAGCGAGACGAGTTACATCAACAAACTCCGACGCC
TTGCTCAACGGGAGCCGGACTTTATTGATATACACGCTCATCTGGCATATGCATTTCTGGAACAGAATGCCCCGCGTAAG
GCACTGAACGCCGCTCTTAAAGGACTGGCGGCAGGTAATCGTATCATCCCGGAAAGTTTCTGTGGTGAAATAATCTGGAT
GCATCCCGAAAACCGGCCTTATCTACGCGCGCTTTATGCAGCAATTCTCGCAAATGTGCACTTACAGCGCCATCAGGATG
CGGTTATGCTCACTGATAAAATACTGGCATACAATCCTGAAGATAATCAGGGGGCTCGCTGGTTGTTGGGTTCAGAGCTG
TTACGCACCGGCGATCATGAGCGAGCCTTCAGTGTACTGAAAGAGCATGCTGATGAATTTTCACCTTACTGGTATGAACT
CGGTCTCCTGCATTTTCTGAACGGGGAACATGTTAAGGCCGCCACAGCTTTTCGCCATGGCTTTGCCACAAACACTTACA
TCGCAGAAATGCTGTGCGGAAATCTGCATCCATTTCCACTTGCTGTGTGGCATGACTTCTCCGGCTCTCTGGATACGGCA
GAAGATTACTATGCAACATACTCACCATTATGGGGACAATATTCGGAAGCATTGCTGTTTGTAAACTGGCTCTATAACCA
TTCCTCCGTGCTGCATGAACGATCAGAAATCATTAAATGCGCCGAAATGCTGATTCAGGAAGATGATTTCGAAATATGCG
AAAGTATTTTAAGACAGCAGGAGCACCTGTGGAAAAGAATTGACAAGACACTTTCTGAGGAAATTGTACAGAAATGCAGA
AATATGAACGGTGAATATATCTGGCCCTGGATATTGCCCTTTTCCGCAGCAGGGATAAAACATTCAAGCATCCAGCATCA
GTAG

Protein sequence :
MNDRLCFEVHDNKGYFVFPDTWFGPLLGEFEEVLDAYDADEISETSYINKLRRLAQREPDFIDIHAHLAYAFLEQNAPRK
ALNAALKGLAAGNRIIPESFCGEIIWMHPENRPYLRALYAAILANVHLQRHQDAVMLTDKILAYNPEDNQGARWLLGSEL
LRTGDHERAFSVLKEHADEFSPYWYELGLLHFLNGEHVKAATAFRHGFATNTYIAEMLCGNLHPFPLAVWHDFSGSLDTA
EDYYATYSPLWGQYSEALLFVNWLYNHSSVLHERSEIIKCAEMLIQEDDFEICESILRQQEHLWKRIDKTLSEEIVQKCR
NMNGEYIWPWILPFSAAGIKHSSIQHQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
shiA AAD44731.1 ShiA Virulence SHI-2 Protein 2e-153 99
shiA NP_839237.1 hypothetical protein Virulence SHI-2 Protein 3e-153 99
shiA NP_709438.1 hypothetical protein Virulence SHI-2 Protein 3e-153 99
aec34 AAW51717.1 Aec34 Not tested AGI-3 Protein 2e-149 96
shiA AFX83956.1 ShiA family protein Not tested SE-PAI Protein 5e-136 87
c3557 NP_755432.1 ShiA-like protein Not tested PAI I CFT073 Protein 3e-132 83
ECUMN_3323 YP_002414005.1 SHI-2 pathogenicity island protein Virulence Not named Protein 2e-133 83

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ECIAI39_4190 YP_002410066.1 SHI-2 pathogenicity island protein VFG0599 Protein 1e-153 99
ECIAI39_4190 YP_002410066.1 SHI-2 pathogenicity island protein VFG1694 Protein 1e-132 83