Gene Information

Name : arsB (ECIAI39_3994)
Accession : YP_002409886.1
Strain : Escherichia coli IAI39
Genome accession: NC_011750
Putative virulence/resistance : Resistance
Product : arsenite/antimonite transporter
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1055
EC number : -
Position : 4151044 - 4152333 bp
Length : 1290 bp
Strand : +
Note : Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15004242, 95355341, 1535622, 7721697; Product type t : transporter

DNA sequence :
ATGTTACTGGCAGGCGCTATTTTTGTCCTGACCATCGTATTGGTTATCTGGCAGCCGAAAGGTTTAGGCATCGGCTGGAG
TGCGACACTGGGCGCCGTACTGGCGTTAGTTACTGGCGTGGTCCATCCGGGCGATATTCCGGTGGTGTGGAATATCGTCT
GGAACGCGACGGCGGCGTTTATAGCCGTCATTATCATCAGCTTGCTGCTGGATGAGTCCGGCTTTTTTGAATGGGCGGCG
CTGCACGTCTCACGCTGGGGCAATGGGCGCGGTCGCTTGCTGTTTACCTGGATTGTCCTGCTCGGTGCTGCCGTTGCAGC
TCTGTTTGCCAATGATGGCGCGGCGCTTATTTTGACACCGATTGTCATCGCCATGCTGCTGGCTTTAGGGTTCAACAAAG
GCACTACGCTGGCGTTTGTTATGGCGGCCGGATTCATTGCCGATACCGCCAGCCTGCCGCTTATTGTCTCTAACCTGGTT
AATATCGTTTCGGCAGATTTCTTTGGCCTCGGCTTTCGCGAATACGCATCGGTGATGGTGCCGGTGGATATCGCTGCAAT
ACTGGCTACCCTGGTGATGTTGCATCTCTATTTCCGCAAAGATATTCCGCAGAACTACGACATGGCGCTGCTAAAATCTC
CCGCAGATGCGATTAAAGATCCTGCGACGTTCAAAACTGGCTGGGTTGTTTTACTGCTTCTGCTGGTGGGATTTTTCGTC
CTGGAACCGCTCGGCATTCCGGTAAGCGCCATTGCGGCAGTGGGCGCGCTGATATTATTTGCCGTCGCTAAACGCGGTCA
TGCGATTAATACGGGTAAAGTGCTGCGCGGTGCGCCCTGGCAGATTGTCATCTTCTCGCTCGGCATGTATCTGGTGGTTT
ATGGCCTGCGCAATGCCGGACTAACGGAATATCTTTCTGGCGTACTCAACGTGCTGGCGGATAACGGCCTGTGGGCGGCG
ACGCTCGGCACCGGATTCCTCACCGCCTTCCTCTCTTCTATTATGAACAATATGCCGACGGTACTGGTTGGCGCGTTGTC
CATTGATGGCAGCACGGCATCTGGTGTCATCAAAGAAGCGATGGTTTATGCCAACGTAATTGGCTGCGATTTGGGGCCGA
AAATTACACCGATTGGTAGCCTGGCAACGCTGCTCTGGCTGCACGTACTTTCGCAGAAGAATATGACTATCAGCTGGGGA
TATTACTTCCGTACAGGGATTATCATGACCATGCCGGTGCTGTTTGTGACGCTCGCCGCGCTGGCGCTTCGTCTCTCTTT
CACTTTGTAA

Protein sequence :
MLLAGAIFVLTIVLVIWQPKGLGIGWSATLGAVLALVTGVVHPGDIPVVWNIVWNATAAFIAVIIISLLLDESGFFEWAA
LHVSRWGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFNKGTTLAFVMAAGFIADTASLPLIVSNLV
NIVSADFFGLGFREYASVMVPVDIAAILATLVMLHLYFRKDIPQNYDMALLKSPADAIKDPATFKTGWVVLLLLLVGFFV
LEPLGIPVSAIAAVGALILFAVAKRGHAINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNVLADNGLWAA
TLGTGFLTAFLSSIMNNMPTVLVGALSIDGSTASGVIKEAMVYANVIGCDLGPKITPIGSLATLLWLHVLSQKNMTISWG
YYFRTGIIMTMPVLFVTLAALALRLSFTL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arsB2 YP_001007633.1 arsenical pump membrane protein Not tested YAPI Protein 1e-156 92
arsB YP_005754065.1 arsenical pump membrane protein Not tested Type-XI SCCmec Protein 1e-94 60
arsB YP_252017.1 arsenical pump membrane protein Not tested SCCmec Protein 7e-96 60
SH0109 YP_252024.1 arsenical pump membrane protein Not tested SCCmec Protein 8e-99 59

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
arsB YP_002409886.1 arsenite/antimonite transporter BAC0576 Protein 4e-160 94
arsB YP_002409886.1 arsenite/antimonite transporter BAC0578 Protein 7e-161 94
arsB YP_002409886.1 arsenite/antimonite transporter BAC0031 Protein 5e-156 91
arsB YP_002409886.1 arsenite/antimonite transporter BAC0577 Protein 9e-155 90
arsB YP_002409886.1 arsenite/antimonite transporter BAC0575 Protein 8e-100 60
arsB YP_002409886.1 arsenite/antimonite transporter BAC0574 Protein 2e-96 60