Gene Information

Name : kpsC (ECIAI39_3437)
Accession : YP_002409347.1
Strain : Escherichia coli IAI39
Genome accession: NC_011750
Putative virulence/resistance : Virulence
Product : capsule polysaccharide export protein
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG3563
EC number : -
Position : 3587866 - 3589893 bp
Length : 2028 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8397187, 8326861; Product type t : transporter

DNA sequence :
ATGATTGGCATTTACTCGCCTGGCATCTGGCGTATTCCGCATCTGGAGAAATTTCTGGCGCAACCGTGCCAGAAACTTTC
TCTGCTGCGCCCTGTTCCGCAAGAAGTTGATGCTATCGCCGTGTGGGGACATCGTCCCAGCGCGGCGAAACCAGTCGCCA
TCGCCAAAGCAGCGGGAAAACCCGTCATTCGTCTGGAAGATGGATTTGTGCGTTCGCTGGATCTTGGCGTCAATGGCGAG
CCGCCGCTTTCTCTGGTGGTGGATGATTGTGGCATTTACTACGATGCCAGCAAGCCTTCAGCACTGGAGAAACTGGTACA
GGATAAAGCCGGAAATACAGCTCTGATAAGCCAGGCCAGAGAAGCGATGCACACCATCGTGACCGGGGATTTGTCGAAAT
ATAACCTGGCACCTGCGTTTGTGGCTGATGAGTCAGAACGTGCAGACATCGTTCTGGTTGTCGATCAGACATTTAATGAT
ATGTCAGTGACGTATGGCAATGCTGGCCCGCATGAGTTTGCTGCCATGCTGGAAGCCGCGATGGCGGAAAATCCTCAAGC
CGAAATTTGGGTGAAGGTGCACCCAGATGTACTGGAAGGAAAGAAAACAGGTTATTTCGCTGATCTGCGTGCCACGCAAC
GAGTACGTTTGATTGCCGAGAATGTCAGCCCGCAGTCGCTATTGCGACACGTTTCCCAGGTTTACGTCGTGACCTCCCAG
TACGGCTTTGAAGCCTTGCTGGCAGGAAAACCAGTAACATGTTTCGGCCAGCCTTGGTATGCAGGTTGGGGTTTAACCGA
CGATCGTCATCCACAGTCCGCTTTGTTATCTGCCCGACGCGGTTCTGCCACGCTGGAGGAACTTTTTGCCGCTGCATACC
TGCGTTACTGTCGCTATATCGATCCGCAAACGGGAGAAGTAAGCGATCTATTTACCGTGCTGCAATGGCTGCAATTACAA
CGTCGACATCTGCAACAGCGTGATGGTTATTTATGGGCGCCAGGCTTAACGCTGTGGAAGTCAGCGATCCTGAAACCTTT
CTTGCAAACGGCAACAAACCGGCTGAGTTTTTCACGTCGCTGTACTGCGGCGAGCGCCTGCGTGGTATGGGGTGTAAAGG
GAGAACAGCAATGGCGAGCCGAAGCGCAGCGAAAATCACTGCCGTTATGGCGAATGGAAGATGGTTTTCTGCGTTCATCC
GGACTTGGCTCTGACCTGCTGCCGCCGCTATCGCTGGTGCTGGATAAACGCGGTATTTACTATGACGCCACACGCCCCAG
CGATCTGGAAGTGCTGCTGAATCATAGCCAGCTAACGCTGGCGCAGAAGATGCGAGCTGAAAAATTACGCCAGCGACTGG
TTGAAAGCAAACTGAGTAAGTACAACCTGGGAGCCGATTTCTCTCTACCAGCCGAAGCCAAAGATAAAAAAGTTATCCTG
GTGCCGGGTCAGGTAGAGGACGATGCCTCTATTAAAACAGGCACTGTCTCGATTAAGAGCAACCTTGAGTTATTACGCAC
AGTACGCGAGCGCAATCCGCACGCCTACATTGTTTATAAACCGCACCCGGATGTACTGGTGGGGAATCGCAAGGGCGATA
TTCCGGCAGAACTGACTGCTGAACTCGCTGATTATCAGGCACTGGACGCCGATATTATTCAATGCATTCAGCGCGCAGAT
GAAGTGCACACCATGACATCATTGTCCGGGTTTGAAGCGTTATTACATGGCAAGCACGTACATTGTTACGGCCTGCCCTT
CTATTCCGGTTGGGGTTTAACCGTCGATGAACATCGCTGCCCGCGTCGCGAGCGAAAATTAACGTTAGCGGATTTGATCT
ATCAGGCGCTGATTGTTTATCCAACCTATATCCACCCAACACGGCTACAACCTATTACGGTTGAAGAGGCGGCGGAATAT
TTGATCCAGACGCCGCGCAAGCCGTTGTTTATTACCAGAAAAAAAGCGGGGCGAGTAATACGTTATTACCGCAAATTAAT
TATGTTCTGCAAGGTCAGATTTGGCTAA

Protein sequence :
MIGIYSPGIWRIPHLEKFLAQPCQKLSLLRPVPQEVDAIAVWGHRPSAAKPVAIAKAAGKPVIRLEDGFVRSLDLGVNGE
PPLSLVVDDCGIYYDASKPSALEKLVQDKAGNTALISQAREAMHTIVTGDLSKYNLAPAFVADESERADIVLVVDQTFND
MSVTYGNAGPHEFAAMLEAAMAENPQAEIWVKVHPDVLEGKKTGYFADLRATQRVRLIAENVSPQSLLRHVSQVYVVTSQ
YGFEALLAGKPVTCFGQPWYAGWGLTDDRHPQSALLSARRGSATLEELFAAAYLRYCRYIDPQTGEVSDLFTVLQWLQLQ
RRHLQQRDGYLWAPGLTLWKSAILKPFLQTATNRLSFSRRCTAASACVVWGVKGEQQWRAEAQRKSLPLWRMEDGFLRSS
GLGSDLLPPLSLVLDKRGIYYDATRPSDLEVLLNHSQLTLAQKMRAEKLRQRLVESKLSKYNLGADFSLPAEAKDKKVIL
VPGQVEDDASIKTGTVSIKSNLELLRTVRERNPHAYIVYKPHPDVLVGNRKGDIPAELTAELADYQALDADIIQCIQRAD
EVHTMTSLSGFEALLHGKHVHCYGLPFYSGWGLTVDEHRCPRRERKLTLADLIYQALIVYPTYIHPTRLQPITVEEAAEY
LIQTPRKPLFITRKKAGRVIRYYRKLIMFCKVRFG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsC YP_854335.1 capsule polysaccharide export protein KpsC Not tested PAI I APEC-O1 Protein 0.0 99
kpsC AAZ04470.1 capsule polysaccharide export protein Virulence PAI I APEC-O1 Protein 0.0 99
kpsC CAE85214.1 KpsC protein Virulence PAI V 536 Protein 5e-176 93
lipA NP_273145.1 capsule polysaccharide modification protein Not tested IHT-A Protein 2e-127 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
kpsC YP_002409347.1 capsule polysaccharide export protein VFG0259 Protein 9e-128 50
kpsC YP_002409347.1 capsule polysaccharide export protein VFG0692 Protein 6e-118 48
kpsC YP_002409347.1 capsule polysaccharide export protein VFG0704 Protein 3e-105 48