Gene Information

Name : iucB (ECIAI39_3424)
Accession : YP_002409336.1
Strain : Escherichia coli IAI39
Genome accession: NC_011750
Putative virulence/resistance : Virulence
Product : aerobactin siderophore biosynthesis N(6)-hydroxylysine acetylase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1670
EC number : -
Position : 3570901 - 3571848 bp
Length : 948 bp
Strand : +
Note : Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3087960; Product type e : enzyme

DNA sequence :
ATGTCTGAGGCAAACATTATTCACAGCAGATATGGACTGCGCTGTGAAAAACTCGACAAGCCCCTGAATCTTGGCTGGGG
ACTGGACAATAGCGCGGTGTTGCACTGTCCCGGGGAGCTGCCGACAGGGTGGCTGTGCGATGCGCTGGATCAGATATTTA
TCGCCGCACCACAACTGTCAGCAGTGGCTCTCCCCTGGGCCGAATGGCGTGAGGAGCCACAGGCGCTGACGCTTTTTGGG
CAGGTAAAAAGCGACATTATCCATCGTACTGCCTTCTGGCAGTTACCGTTATGGTTGAGTTCACCGGCAAACCGGGCCTC
CGGTGAAATGGTTTTTGATGCAGAGCGTGAGATTTATTTCCCGCAGCGCCCACCCCGTCCACAGGGTGAGGTTTACCGCC
GTTACGATCCACGTATTCGCAGGATGCTGAGTTTCCGCATTGCCGATCCCGTTTCTGATGCAGAACGTTTCACCCGCTGG
ATGAATGATCCGCGCGTTGAGTATTTCTGGGAGCAAAGTGGCTCACTGGAGGTACAGACCGCCTATCTGGAGCGCCAGCT
CACCGGTAAACATGCATTCCCGCTGATTGGGTGCTTCGACGATCGGCCATTCAGCTATTTCGAAATCTACTGGGCGGCGG
AAGACCGCATTGGTCGTCACTATTCGTGGCAGCCCTTTGACCGTGGCCTGCATCTGCTGGTTGGTGAACAGCAATGGCGC
GGGGCCCACTATGTGCAAAGCTGGCTGCGCGGGCTGACACATTACCTGCTGCTGGATGAGCCCCGTACGCAGCGCACAGT
ACTGGAGCCACGCACCGATAACCAGCGCCTGTTCCGCCATCTTGAGCCTGCGGGATACCGGACAATTAAAGAGTTCGACT
TCCCACATAAGCGCTCGCGCATGGTGATGGCGGATCGTCATCACTTCTTCACGGAGGTCGGTCTGTAA

Protein sequence :
MSEANIIHSRYGLRCEKLDKPLNLGWGLDNSAVLHCPGELPTGWLCDALDQIFIAAPQLSAVALPWAEWREEPQALTLFG
QVKSDIIHRTAFWQLPLWLSSPANRASGEMVFDAEREIYFPQRPPRPQGEVYRRYDPRIRRMLSFRIADPVSDAERFTRW
MNDPRVEYFWEQSGSLEVQTAYLERQLTGKHAFPLIGCFDDRPFSYFEIYWAAEDRIGRHYSWQPFDRGLHLLVGEQQWR
GAHYVQSWLRGLTHYLLLDEPRTQRTVLEPRTDNQRLFRHLEPAGYRTIKEFDFPHKRSRMVMADRHHFFTEVGL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
iucB NP_839222.1 siderophore biosynthesis protein Virulence SHI-2 Protein 4e-148 100
iucB NP_709455.1 siderophore biosynthesis protein Virulence SHI-2 Protein 4e-148 100
iucB AAK71632.1 IucB Virulence SHI-3 Protein 3e-148 100
iucB YP_002414045.1 aerobactin siderophore biosynthesis protein, N(6)-hydroxylysine acetylase Virulence Not named Protein 5e-147 99
iucB AAD44747.1 IucB Virulence SHI-2 Protein 3e-148 99

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
iucB YP_002409336.1 aerobactin siderophore biosynthesis N(6)-hydroxylysine acetylase VFG0616 Protein 2e-148 100
iucB YP_002409336.1 aerobactin siderophore biosynthesis N(6)-hydroxylysine acetylase VFG1082 Protein 2e-148 100
iucB YP_002409336.1 aerobactin siderophore biosynthesis N(6)-hydroxylysine acetylase VFG0939 Protein 2e-147 99