Gene Information

Name : insD (ECIAI39_3421)
Accession : YP_002409333.1
Strain : Escherichia coli IAI39
Genome accession: NC_011750
Putative virulence/resistance : Unknown
Product : IS2 insertion element transposase InsAB'; CP4-44 prophage
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG2801
EC number : -
Position : 3566829 - 3567734 bp
Length : 906 bp
Strand : +
Note : Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689094; Product type h : extrachromosomal origin

DNA sequence :
GTGGATAGCGCACGCGCCCTTATTGCCCGGGGATGGGGAGTAAGCTTCGTCAGCCGTTGTCTCCGGGTGTCGCGTGCGCA
GTTGCACGTCATTCTCAGACGAGCCGATGACTGGAAGGACGGCCGCCGCAGCCGTCACACGGATGATACGGATGTGCTTC
GCCGTATACACCATGTTATCGGGGAGCTGCCCACGTATGGTTATCGTCGGGTATGGGCGCTGCTTCGCAGACAAACAGAA
CTTGATGGTATGCCTGCGATCAATGCCAAACGTGTTTACCGGATCATGCGCCAGAATGCGCTGTTGCTTGAGCGAAAAAC
CGCTGTACCGCCATCGAAACGGGCACATACCGGCAGAGTGGCTGTGAAAGAAAGTAATCAGCGATGGTGCTCTGACGGGT
TCGAGTTCCGCTGTGATAACGGAGAAAAACTGCGAGTCACGTTCGCGCTGGACTGCTGTGACCGTGAGGCACTGCACTGG
GCGGTCACTACGGGCGGCTTCAACAGTGAAACAGTACAGGACGTCATGCTGGGAGCGGTGGAACGCCGCTTCGGCAACGA
GCTTCCGGCGTCTCCAGTAGAGTGGCTGACGGATAATGGTTCATGCTACCGGGCTAATGAAACACGGCAGTTTGCCCGGA
TGTTGGGGCTTGAACCGAAAAACACGGCGGTGCGGAGTCCGGAGAGTAACGGCATAGCAGAGAGCTTCGTGAAAACGATA
AAGCGTGACTACATAAGTATCATACCCAAACCAGACGGGTTAACGGCAGCAAAGAACCTTGCAGAGGCGTTCGAGCATTA
TAACGAATGGCATCCGCATAGTGCGTTGGGTTATCGCTCGCCACGGGAATATCTGCGGCAGCGGGCCTGTAATGGGTTAA
GTGATAACAGATGTCTGGAAATATAG

Protein sequence :
MDSARALIARGWGVSFVSRCLRVSRAQLHVILRRADDWKDGRRSRHTDDTDVLRRIHHVIGELPTYGYRRVWALLRRQTE
LDGMPAINAKRVYRIMRQNALLLERKTAVPPSKRAHTGRVAVKESNQRWCSDGFEFRCDNGEKLRVTFALDCCDREALHW
AVTTGGFNSETVQDVMLGAVERRFGNELPASPVEWLTDNGSCYRANETRQFARMLGLEPKNTAVRSPESNGIAESFVKTI
KRDYISIIPKPDGLTAAKNLAEAFEHYNEWHPHSALGYRSPREYLRQRACNGLSDNRCLEI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AAL67379.1 transposase-like protein Not tested PAI II CFT073 Protein 5e-119 98
insD YP_002414033.1 insertion element IS2 transposase InsD Not tested Not named Protein 3e-136 98
tnpF AAD44739.1 TnpF Not tested SHI-2 Protein 1e-117 97
S4050 NP_839218.2 insertion element IS2 transposase InsD Not tested SHI-2 Protein 6e-135 97
unnamed CAC39284.1 hypothetical protein Not tested LPA Protein 5e-118 97
SF3708 NP_709447.1 IS2 transposase TnpB Not tested SHI-2 Protein 6e-135 97
SF3721 NP_709460.1 IS2 transposase TnpB Not tested SHI-2 Protein 6e-135 97
S4061 NP_839230.2 insertion element IS2 transposase InsD Not tested SHI-2 Protein 3e-135 97
S3189 NP_838472.2 insertion element IS2 transposase InsD Not tested SHI-1 Protein 7e-134 96
SF2985 NP_708759.1 insertion element IS2 transposase InsD Not tested SHI-1 Protein 2e-116 96
ECO111_3773 YP_003236109.1 putative IS2 transposase InsAB Not tested LEE Protein 4e-120 94
aec49 AAW51732.1 Aec49 Not tested AGI-3 Protein 1e-120 84
unnamed CAC39283.1 hypothetical protein Not tested LPA Protein 1e-83 63
c5197 NP_757045.1 transposase insD Not tested PAI II CFT073 Protein 3e-62 60
insD YP_854263.1 IS2 transposase Not tested PAI I APEC-O1 Protein 5e-66 60
insD AAZ04432.1 IS2 transposase Not tested PAI I APEC-O1 Protein 4e-66 60

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
insD YP_002409333.1 IS2 insertion element transposase InsAB'; CP4-44 prophage VFG1732 Protein 1e-136 98
insD YP_002409333.1 IS2 insertion element transposase InsAB'; CP4-44 prophage VFG0608 Protein 2e-135 97
insD YP_002409333.1 IS2 insertion element transposase InsAB'; CP4-44 prophage VFG0621 Protein 2e-135 97
insD YP_002409333.1 IS2 insertion element transposase InsAB'; CP4-44 prophage VFG0649 Protein 9e-117 96