Gene Information

Name : intS (ECIAI39_2501)
Accession : YP_002408455.1
Strain : Escherichia coli IAI39
Genome accession: NC_011750
Putative virulence/resistance : Unknown
Product : putative prophage CPS-53 integrase; CPS-53 (KpLE1) prophage
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0582
EC number : -
Position : 2588734 - 2589891 bp
Length : 1158 bp
Strand : +
Note : Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme

DNA sequence : 
ATGCTCACCGTTAAGCAGATTGAAGCAGCAAAGCCGAAAGAAAAACCATACCGCCTACTCGATGGTAATGGCCTGTACCT
TTATGTCCCTGTGTCAGGGAAAAAGGTATGGCAGCTTCGCTACAAGATTGACGGTAAGGAGAAAATCCTGACCGTAGGAA
AATATCCGCTAATGACTTTGCAGGAGGCAAGAGATAAAGCATGGACCGCGAGGAAAGACATCTCGGTTGGCATCGATCCG
GTAAAAGCGAAAAAGGCTTCGTCTAACAACAATTCCTTTAGCGCCATTTACAAGGAATGGTACGAGCACAAGAAGCAAGT
CTGGTCAGTAGGCTATGCAACTGAACTTGCCAAAATGTTTGATGACGACATTTTGCCCATCATCGGCGGTCTTGAGATTC
AGGATATTGAGCCGATGCAACTGCTGGAAGTAATCCGCAGATTTGAAGATCGCGGTGCAATGGAACGAGCCAATAAAGCC
CGCAGAAGATGCGGCGAGGTTTTTCGTTACGCTATTGTCACCGGAAGGGCTAAATATAACCCGGCACCTGACCTTGCAGA
CGCCATGAAAGGATACCGCAAGAAGAACTTCCCGTTTCTTCCAGCAGACCAGATCCCTGCATTCAACAAAGCACTGGCAA
CATTTTCAGGAAGTATCGTATCGCTCATTGCGACCAAAGTCTTACGCTACACAGCCCTAAGAACGAAAGAGCTTCGTTCC
ATGCAATGGAAGAGCGTCGATTTTGAAAACAGGATTATCACCATCGACGCCAGTGTGATGAAGGGACGCAAAATTCATGT
GGTTCCTATGTCAGACCAGGTGGTTGAACTTCTTACTACGCTAAGCTCAATCACCAAACCAGTCTCAGAGTTTGTTTTTG
CCGGGCGCAACGATAAGAAGAAACCAATCTGCGATAACGCGGTATTGCTTGTGATCAAACAAATCGGCTATGAGGGGCTG
GAAAGCGGTCACGGATTCAGGCATGAATTCAGCACGATTATGAACGAGCACGAATGGCCTGCCGACGCCATTGAAGTGCA
ACTGGCACATGCCAACGGCGGATCTGTACGTGGAATTTACAACCATGCTCAGTATCTCGATAAGCGCAGAGAAATGATGC
AGTGGTGGGCGGATTGGCTTGATGAGAAGGTAGAGTGA

Protein sequence : 
MLTVKQIEAAKPKEKPYRLLDGNGLYLYVPVSGKKVWQLRYKIDGKEKILTVGKYPLMTLQEARDKAWTARKDISVGIDP
VKAKKASSNNNSFSAIYKEWYEHKKQVWSVGYATELAKMFDDDILPIIGGLEIQDIEPMQLLEVIRRFEDRGAMERANKA
RRRCGEVFRYAIVTGRAKYNPAPDLADAMKGYRKKNFPFLPADQIPAFNKALATFSGSIVSLIATKVLRYTALRTKELRS
MQWKSVDFENRIITIDASVMKGRKIHVVPMSDQVVELLTTLSSITKPVSEFVFAGRNDKKKPICDNAVLLVIKQIGYEGL
ESGHGFRHEFSTIMNEHEWPADAIEVQLAHANGGSVRGIYNHAQYLDKRREMMQWWADWLDEKVE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
int AAC31482.1 CP4-like integrase Not tested LEE Protein 2e-86 49
int ACU09430.1 integrase Not tested LEE Protein 2e-86 49
intL NP_290239.1 integrase for prophage 933L and the LEE pathogenicity island Not tested LEE Protein 2e-86 49
ECs4534 NP_312561.1 integrase Not tested LEE Protein 2e-86 49
int CAC39282.1 integrase Not tested LPA Protein 3e-86 49
aec33 AAW51716.1 Int Not tested AGI-3 Protein 3e-86 49
SF3698 NP_709437.1 integrase Not tested SHI-2 Protein 2e-85 49
int AAD54663.1 Sai integrase Not tested SHI-2 Protein 2e-85 49
S4835 NP_839238.1 integrase Not tested SHI-2 Protein 2e-85 49
ESA_03025 YP_001439090.1 hypothetical protein Not tested Not named Protein 2e-81 48
int AAD44730.1 Int Not tested SHI-2 Protein 6e-85 48
unnamed AFX83955.1 integrase Not tested SE-PAI Protein 6e-78 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
intS YP_002408455.1 putative prophage CPS-53 integrase; CPS-53 (KpLE1) prophage VFG0783 Protein 9e-87 49
intS YP_002408455.1 putative prophage CPS-53 integrase; CPS-53 (KpLE1) prophage VFG0598 Protein 1e-85 49