Gene Information

Name : yfcS (ECIAI39_2489)
Accession : YP_002408444.1
Strain : Escherichia coli IAI39
Genome accession: NC_011750
Putative virulence/resistance : Virulence
Product : putative periplasmic pilus exported chaperone
Function : -
COG functional category : N : Cell motility
COG ID : COG3121
EC number : -
Position : 2573739 - 2574491 bp
Length : 753 bp
Strand : -
Note : Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor

DNA sequence : 
ATGTCTTATAAATTATCCAGTTCAATGGTCGTCAGCACGGCGCTGGCGGCACTGCTTTCCACCGTCAGCCTGGCGGCGCA
CGCCTCGGTCACCCCGGACCGCACCCGTCTGGTGTTTAACGAAAGCGATAAATCGATCAGCGTGACGTTGCGTAACAACA
ACGAAAAGCTGCCTTACCTGGCGCAAAGCTGGCTGGAAGACGAGAAGGGCAACAAAATCACCTCGCCGCTGGCGGTACTG
CCGCCGGTGCAGCGTATTGACGCCATGATGAACGGCCAGGTGAAGATTCAGGCGCTGCCGGACATTCACACGCTGCCATC
TGACCGTGAAAGCCTGTTCTACTACAACGTGCGTGAGATCCCGCCAAAGACCGGGAAAGCCAACACCCTGCAAATTGCCC
TGCAAACGCGCATCAAGCTGTTCTGGCGACCAAAGGCGCTGGAGAAGATTGACATGAGAAAACCGTGGCAGTTTAAGGTG
ACGCTCACGCGCAGCGGCCAGGACTATACCGTCAATAACCCGACGCCATACCACGTCATCATCAGCGATGCCAGCACACA
GAAGAAAGGGCCGACCGCAGCCGGGTTTAAACCGCTGGTGATGTCGCCGAAAACGTCACAGCCGTTAAAGGCAAAAATGG
ACAGCGCCCCGGTGCTGACCTACATCAACGACTACGGCGCGCGCCTGCCGCTGATCTTCCGCTGTGAAGGGGACACCTGC
AAGGTGGATGAAGATCAAAGCAGCAAAGGCTGA

Protein sequence : 
MSYKLSSSMVVSTALAALLSTVSLAAHASVTPDRTRLVFNESDKSISVTLRNNNEKLPYLAQSWLEDEKGNKITSPLAVL
PPVQRIDAMMNGQVKIQALPDIHTLPSDRESLFYYNVREIPPKTGKANTLQIALQTRIKLFWRPKALEKIDMRKPWQFKV
TLTRSGQDYTVNNPTPYHVIISDASTQKKGPTAAGFKPLVMSPKTSQPLKAKMDSAPVLTYINDYGARLPLIFRCEGDTC
KVDEDQSSKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
prfD CAD42028.1 PrfD protein Virulence PAI II 536 Protein 1e-47 46
papD AAZ04423.1 P pilus chaperone Virulence PAI I APEC-O1 Protein 4e-47 46
papD YP_854253.1 pilus assembly protein chaperone PapD Virulence PAI I APEC-O1 Protein 5e-47 46
pixD CAE85158.1 PixD protein Not tested PAI V 536 Protein 2e-47 46
papD_2 NP_757033.1 PapD protein Virulence PAI II CFT073 Protein 8e-47 45
papD YP_002414014.1 Chaperone protein PapD Not tested Not named Protein 8e-47 45
papD AAL67413.1 PapD Virulence PAI II CFT073 Protein 6e-47 45
papD NP_755464.1 PapD protein Virulence PAI I CFT073 Protein 1e-42 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
yfcS YP_002408444.1 putative periplasmic pilus exported chaperone VFG1547 Protein 8e-48 46
yfcS YP_002408444.1 putative periplasmic pilus exported chaperone VFG0896 Protein 3e-47 45
yfcS YP_002408444.1 putative periplasmic pilus exported chaperone VFG0885 Protein 6e-43 44