Gene Information

Name : cvrA (ECIAI39_1522)
Accession : YP_002407522.1
Strain : Escherichia coli IAI39
Genome accession: NC_011750
Putative virulence/resistance : Unknown
Product : potassium/proton antiporter
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG3263
EC number : -
Position : 1589112 - 1590848 bp
Length : 1737 bp
Strand : -
Note : the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli

DNA sequence :
TTGGATGCCACAACAATAATTAGCCTTTTCATCTTAGGATCCATCCTTGTCACCAGCAGTATATTACTTAGTTCATTTTC
TTCCCGTCTTGGCATTCCTATTCTGGTTATTTTTCTGGCGATCGGCATGCTGGCAGGAGTCGATGGCGTCGGCGGTATCC
CGTTTGATAATTACCCCTTCGCCTACATGGTAAGTAACCTGGCGCTGGCGATTATTTTGCTCGACGGCGGAATGCGCACT
CAGGCCAGTTCCTTTCGTGTGGCATTAGGACCGGCACTGTCGCTGGCGACGCTGGGCGTGCTTATCACCTCTGGTTTAAC
CGGCATGATGGCGGCGTGGCTGTTTAATCTTGATTTGATTGAAGGCTTATTAATCGGCGCTATCGTCGGCTCCACCGATG
CTGCAGCGGTCTTTTCTCTGCTGGGTGGTAAGGGGCTTAACGAACGTGTTGGCTCGACGCTGGAAATTGAATCCGGCAGT
AATGATCCAATGGCGGTCTTTCTGACGATTACCCTGATTGCGATGATCCAGCAACATGAAAGCAGTGTCAGTTGGATGTT
CGTAGTCGATATTCTGCAGCAATTTGGCCTCGGGATTGTCATCGGTCTTGGCGGTGGTTATTTACTGCTGCAAATGATTA
ATCGCATCGCCCTGCCCGCCGGATTATATCCATTGCTGGCATTAAGCGGCGGTATTTTAATTTTTGCTTTAACCACGGCG
CTGGAAGGCAGCGGTATTCTGGCTGTTTATCTGTGCGGTTTTCTGCTGGGTAATCGCCCGATTCGCAACCGCTACGGCAT
TCTGCAAAATTTCGACGGCCTCGCCTGGCTGGCGCAAATCGCCATGTTCCTGGTGCTGGGGCTGTTGGTTAACCCAAGCG
ATCTGCTGCCTATTGCCATTCCGGCGCTCATTTTGTCCGCATGGATGATTTTCTTCGCCCGTCCTCTTTCGGTATTTGCC
GGATTGCTACCATTCCGTGGCTTCAATCTGCGTGAGCGCGTGTTTATCAGCTGGGTGGGATTACGCGGCGCGGTGCCGAT
TATTCTGGCCGTGTTCCCGATGATGGCGGGGCTGGAGAATGCACGTCTGTTCTTTAATGTCGCCTTCTTTGTGGTTCTGG
TTTCACTGCTCTTGCAGGGAACATCACTCTCGTGGGCGGCGAAAAAAGCCAAAGTGGTGGTTCCGCCCGTCGGACGTCCG
GTGTCACGCGTTGGCCTGGATATTCATCCGGAAAATCCGTGGGAGCAGTTTGTTTATCAATTGAGTGCCGATAAATGGTG
CGTGGGCGCGGCACTGCGCGATTTGCATATGCCAAAAGAGACGCGTATTGCGGCACTGTTTCGTGATAACCAGCTGCTTC
ATCCTACCGGCAGCACCCGACTGCGCGAAGGCGATGTATTGTGTGTAATTGGTCGGGAACGCGATCTCCCGGCGCTCGGT
AAACTGTTCAGCCAGTCGCCGCCGGTCGCGCTGGATCAACGCTTCTTTGGTGACTTCATTCTCGAAGCCAGCGCCAAATA
TGCTGATGTGGCGCTGATATATGGTCTGGAAGACGGGCGAGAATATCGCGATAAGCAGCAAACGCTGGGTGAAATCGTCC
AGCAGTTGTTAGGCGCGGCACCGGTTGTCGGTGACCAGGTAGAGTTTGCCGGGATGATCTGGACGGTGGCCGAGAAAGAA
GATAATGAAGTGTTGAAGATTGGCGTACGGGTGGCTGAAGAGGAAGCTGAATCTTAA

Protein sequence :
MDATTIISLFILGSILVTSSILLSSFSSRLGIPILVIFLAIGMLAGVDGVGGIPFDNYPFAYMVSNLALAIILLDGGMRT
QASSFRVALGPALSLATLGVLITSGLTGMMAAWLFNLDLIEGLLIGAIVGSTDAAAVFSLLGGKGLNERVGSTLEIESGS
NDPMAVFLTITLIAMIQQHESSVSWMFVVDILQQFGLGIVIGLGGGYLLLQMINRIALPAGLYPLLALSGGILIFALTTA
LEGSGILAVYLCGFLLGNRPIRNRYGILQNFDGLAWLAQIAMFLVLGLLVNPSDLLPIAIPALILSAWMIFFARPLSVFA
GLLPFRGFNLRERVFISWVGLRGAVPIILAVFPMMAGLENARLFFNVAFFVVLVSLLLQGTSLSWAAKKAKVVVPPVGRP
VSRVGLDIHPENPWEQFVYQLSADKWCVGAALRDLHMPKETRIAALFRDNQLLHPTGSTRLREGDVLCVIGRERDLPALG
KLFSQSPPVALDQRFFGDFILEASAKYADVALIYGLEDGREYRDKQQTLGEIVQQLLGAAPVVGDQVEFAGMIWTVAEKE
DNEVLKIGVRVAEEEAES

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
f536 AAC61706.1 F536 Not tested PAI I CFT073 Protein 0.0 99
unnamed AAB61290.1 unknown Not tested PAI I CFT073 Protein 0.0 99