Gene Information

Name : irp (ECIAI39_1073)
Accession : YP_002407086.1
Strain : Escherichia coli IAI39
Genome accession: NC_011750
Putative virulence/resistance : Virulence
Product : Thiazolinyl-S-HMWP1 reductase YbtU
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG4693
EC number : -
Position : 1137102 - 1138262 bp
Length : 1161 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11927258; Product type e : enzyme

DNA sequence :
TTGTGCGCAACACATTACGCGCTGGCTTTGCGCAACCTCAACGCAACCGGAGAACACGTTATGATGCCGTCCGCCTCCCC
AAAACAACGTGTACTGATTGTGGGCGCCAAATTTGGCGAAATGTACCTGAATGCCTTTATGCAGCCCCCGGAGGGGCTGG
AACTGGTCGGCCTGCTGGCGCAGGGAAGCGCCCGTTCAAGAGAGCTGGCTCATGCGTTTGGCATTCCGCTGTATACCTCG
CCGGAACAGATAACCAGGATGCCGGATATCGCCTGTATTGTCGTGCGTTCGACCGTCGCCGGAGGAACCGGTACGCAGCT
TGCCAGACACTTTCTGACGCGCGGCGTACACGTCATTCAGGAGCATCCCCTCCACCCGGATGACATCAGTTCCTTACAAA
CGCTGGCGCAGGAACAGGGCTGCTGCTATTGGGTAAACACGTTTTATCCGCATACGCGCGCGGGACGCACATGGCTTCGC
GATGCGCAGCAGCTGCGTCGCTGCCTGGCTAAGACGCCGCCGGTAGTCCACGCCACCACCAGCCGACAGTTGCTCTACTC
CACTCTGGATTTGTTGTTGCTGGCTCTGGGCGTTGATGCCGCCGCCGTGGAGTGCGACGTGGTTGGCAGCTTTAGCGATT
TTCACTGTCTGAGACTCTTCTGGCCGGAGGGAGAAGCCTGCCTGCTGCTTCAGCGCTATCTCGATCCTGACGATCCAGAT
ATGCATAGCCTTATCATGCACCGCCTGCTGCTGGGCTGGCCGGAAGGTCATCTTTCGCTGGAGGCGAGCTACGGCCCCGT
CATTTGGTCATCCAGTCTGTATGTCGCAGACCATCAGCAGAACCCCCACAGTCTCTGGCGCAGACCGGAGATCCTGCGCG
ATCTGCCGGGTCTGACGCGCAGCGCGGCGCCCCTGAGCTGGCGCGACTGCTGCGAAACCGTCGGGCCGGAGGGCGTCAGC
TGGTTGCTACACCAGTTGCGCAGCAATCTGGCGGGCGAACATCCACCAGCGGCCTGCCAAAGCGTACATCAGATCGCGTT
ATCACGTTTATGGCAGCAGATTTTACGTAAGACCGGCAATGCGGAGATCAGACGCCTGACGCCGCCGCACCACGACCGGT
TAGCCGGTTTCTACAACGATGATGATAAGGAGGCGCTGTGA

Protein sequence :
MCATHYALALRNLNATGEHVMMPSASPKQRVLIVGAKFGEMYLNAFMQPPEGLELVGLLAQGSARSRELAHAFGIPLYTS
PEQITRMPDIACIVVRSTVAGGTGTQLARHFLTRGVHVIQEHPLHPDDISSLQTLAQEQGCCYWVNTFYPHTRAGRTWLR
DAQQLRRCLAKTPPVVHATTSRQLLYSTLDLLLLALGVDAAAVECDVVGSFSDFHCLRLFWPEGEACLLLQRYLDPDDPD
MHSLIMHRLLLGWPEGHLSLEASYGPVIWSSSLYVADHQQNPHSLWRRPEILRDLPGLTRSAAPLSWRDCCETVGPEGVS
WLLHQLRSNLAGEHPPAACQSVHQIALSRLWQQILRKTGNAEIRRLTPPHHDRLAGFYNDDDKEAL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtU YP_070122.1 yersiniabactin biosynthetic protein YbtU Virulence HPI Protein 5e-160 99
ybtU CAA21392.1 - Virulence HPI Protein 2e-159 99
ybtU YP_853077.1 yersiniabactin biosynthetic protein Virulence PAI IV APEC-O1 Protein 6e-160 99
irp3 YP_002346900.1 yersiniabactin biosynthetic protein YbtU Virulence HPI Protein 5e-160 99
ybtU NP_669708.2 thiazolinyl-S-HMWP1 reductase Virulence HPI Protein 5e-160 99
ybtU NP_993005.2 yersiniabactin biosynthetic protein YbtU Virulence HPI Protein 5e-160 99
irp3 YP_001006817.1 yersiniabactin biosynthetic protein YbtU Virulence HPI Protein 1e-160 97
irp3 CAA73128.1 Irp3 protein Virulence HPI Protein 6e-160 97
nrpU YP_002152319.1 siderophore biosynthetic protein Virulence Not named Protein 6e-62 43