Gene Information

Name : ibrA (ECIAI39_1046)
Accession : YP_002407064.1
Strain : Escherichia coli IAI39
Genome accession: NC_011750
Putative virulence/resistance : Virulence
Product : immunoglobulin-binding regulator
Function : -
COG functional category : R : General function prediction only
COG ID : COG3969
EC number : -
Position : 1108148 - 1109332 bp
Length : 1185 bp
Strand : +
Note : Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12057959; Product type r : regulator

DNA sequence :
ATGTTAATGTATTACATGCGGCCATTCACCGTATTGAGTGGATTTTCATCTGTTTGTTTGTCTTTTTCTGGAGGAAAAGA
CTCTACTGTGCTGCTCCATCTTACGGCCGATGTGGCTCGCAGGAAGAAACGTCGTTTCTCTGTATTATTCATTGACTGGG
AAGCTCAGTACCAGTGCACAATTGCACACATTCTGAAGATGAGGGAGATGTATCGGGATGTGACGGAGACTTTTTACTGG
GTGGCACTCCCCCTGACTACGGTAAACGGTGTCTCTCAGTTTCAGCCGGAATGGATATGCTGGGAACCAGGTGTGGAGTG
GGTTCGTCAGCCACCAGATGACGCTATTACAGATATGTCGTATTTCCCATTTTATCGGTATGCCATGACGTTTGAAGAAT
TTGTTCCGGCATTTTCTTCCTGGTTTGCCGGTAACCGGTGTGGAGTGGCAATACTGACTGGTGTTCGTGCTGATGAATCG
CTCAATCGCTTTATGGGACTGGTGTCTCAGCGCAAACTGAGATATGCAGATGATAAACCCTGGACCACAGCGTCACCTGA
AGGGTTTTATTACACCTTGTATCCGTTGTATGACTGGAAAGCCCGTGATATATGGATATATAACGCCAGAACCCGAGCTA
TCTACAATCCCCTGTATGACCTGATGTACCGTGCCGGCGTGCCGTTACGCAACATGCGGGTCTGTGAGCCTTTTGGCCCG
GAACAGCGTAAGGGACTGTGGCTTTACCATGTTCTGGAGCCGGAAACCTGGGCCAGGATGTGTGAGCGGGTGTCGGGTGC
TGCCAGCGGGGCGCTTTATGCCAATGAGAGCGGTGCCTATTTTGCCCTGCGTAAGCGTATCACGAAGCCGCCTCATCATA
CCTGGCGTAGCTATGCGATGTTCCTGCTGGATGTGATGCCGGAAAGAACGGCAGAACATTACCGTAATAAAATTGCTGTC
TACCTGCGCTGGTATCAGACGCGGGGCTTCCCGGATGACATCCCGGATGAACAGGAGAATGACCTGGGGAGCCGGGATAT
CCCGTCCTGGCGACGTATCTGTAAGACACTCATAAAGAATGATTTCTGGTGCCGGACCCTCTCCTTCAGTCCGAACAAAC
CCCGGCACTATGAACGTTATCTGCAGCGTATGAAAGAAAGGAGGAAGGAATGGGGGATTCTGTGA

Protein sequence :
MLMYYMRPFTVLSGFSSVCLSFSGGKDSTVLLHLTADVARRKKRRFSVLFIDWEAQYQCTIAHILKMREMYRDVTETFYW
VALPLTTVNGVSQFQPEWICWEPGVEWVRQPPDDAITDMSYFPFYRYAMTFEEFVPAFSSWFAGNRCGVAILTGVRADES
LNRFMGLVSQRKLRYADDKPWTTASPEGFYYTLYPLYDWKARDIWIYNARTRAIYNPLYDLMYRAGVPLRNMRVCEPFGP
EQRKGLWLYHVLEPETWARMCERVSGAASGALYANESGAYFALRKRITKPPHHTWRSYAMFLLDVMPERTAEHYRNKIAV
YLRWYQTRGFPDDIPDEQENDLGSRDIPSWRRICKTLIKNDFWCRTLSFSPNKPRHYERYLQRMKERRKEWGIL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
z1203 CAD33763.1 Z1203 protein Not tested PAI I 536 Protein 1e-176 96
ibrA ADD91735.1 putative phosphoadenosine phosphosulfate reductase IbrA Not tested PAI-I AL862 Protein 2e-174 95
Z1643 AAQ19139.1 putative phosphoadenosine phosphosulfate reductase Not tested PAI I CL3 Protein 7e-175 95
APECO1_3502 YP_854308.1 hypothetical protein Not tested PAI I APEC-O1 Protein 5e-175 94
c5209 NP_757057.1 hypothetical protein Not tested PAI II CFT073 Protein 5e-175 94
ORF_31 AAZ04441.1 conserved hypothetical protein Not tested PAI I APEC-O1 Protein 3e-175 94
Z1203 NP_286738.1 hypothetical protein Not tested TAI Protein 1e-173 93
Z1643 NP_287146.1 hypothetical protein Not tested TAI Protein 1e-173 93
t4277 NP_807875.1 hypothetical protein Not tested SPI-7 Protein 2e-169 89
STY4583 NP_458667.1 conserved hypothetical protein Not tested SPI-7 Protein 2e-169 88

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ibrA YP_002407064.1 immunoglobulin-binding regulator VFG1504 Protein 7e-177 96