Gene Information

Name : iucA (EC55989_4645)
Accession : YP_002405520.1
Strain : Escherichia coli 55989
Genome accession: NC_011748
Putative virulence/resistance : Virulence
Product : aerobactin siderophore biosynthesis protein
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG4264
EC number : -
Position : 4761351 - 4763138 bp
Length : 1788 bp
Strand : -
Note : Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3087960; Product type e : enzyme

DNA sequence :
TTGATAATGAGAATCATTATTGACATAATTGTTATTATTTTACTGTGTGGGAGCTGTTTGACTATGACCCTGCCCTCTGA
AAAACCAGCCACAGATGTGGCTGCGCAGTGCTTCCTGAATGCACTGATTCGTGAAACCACAGACTGGAAACTGACAGAAT
ACCCGCCAGACGAATTGATCATCCCGCTGGATGAGCAGAAATCGCTCCATTTCAGAGTGGCTTATTTCTCCCCAACCCAG
CATCACCGCTTTGCATTTCCTGCACGTCTGGTCACGGCATCAGGCAGTTATCCTGTCGACTTTACCACTCTCTCCCGGCT
TATTATTGATAAGCTACGGCATCAACTGTTTCTGCCCGTTCCCCTCTGCGAAACTTTCCACCAGCGCGTGCTGGAAAGCC
ACGCCCATACGCAACAGACAATTGATGCCCGTCATGACTGGACCGCCCTGCGTGAAAAAGCGTTGAATTTTGGCGAAGCT
GAGCAGGCGCTGCTGACAGGACACGCTTTCCACCCTGCGCCTAAGTCTCATGAACCGTTTAACCGGCGGGAGGCTGAACG
CTACCTGCCTGATATGGCACCCCACTTCCCACTGCGGTGGTTTTCGGTGGATAAAACGCAAATCGCCGGTGAAAGTTTGC
ATCTCAACCTTCAACAGCGGCTGACGCGATTTGCCGCAGAGAATGCGCCTCAGTTACTCAACGAATTAAGTGACAACCAA
TGGCTGTTCCCGTTGCACCCGTGGCAGGGGGAATATCTTTTGCAGCAGGGGTGGTGCCAGGCACTTGTTGCTAAAGGGCT
GATTAAAGACTTAGGTGAGGCCGGCACGTCGTGGCTGCCGACCACCTCTTCCCGTTCCCTCTACTGTGCCACCAGCCGCG
ATATGATCAAGTTCTCCCTGAGCGTACGGCTGACCAACTCCATCCGTACTCTGTCCGTGAAAGAAGTGAAGCGTGGGATG
CGCCTGGCACGCCTGGCTCAAACCGACGGCTGGCAGATGCTACAGGTCCGCTTCCCGACTTTCCGGGTAATGCAGGAGGA
TGGCTGGGCCGGGCTGCTCGATCTTAACGGCAACATCATGCAGGAAAGTCTGTTTGCCCTGCGTGAAAATCTGCTGGTGG
ATCAGCCGAAAAGCCAGACCAACGTACTGGTCTCCCTGACTCAGGCCGCACCTGATGGCGGTGATTCGCTGCTGGTTTCG
GCGGTAAAACGCCTGAGCGATCGCCTCGGTATCACTGTGCAACAGGCCGCCCATGCATGGGTCGATGCATACTGTCAGCA
AGTGCTAAAGCCGCTGTTTACGGCTGAAGCGGATTACGGCCTGGTGCTGCTGGCGCATCAGCAAAATATTCTTGTCCAGA
TGCTTGGGGATCTGCCGGTCGGATTTATTTACCGTGACTGTCAGGGCAGCGCTTTTATGCCTCACGCGACAGACTGGCTC
GATTCTATTGGCGAGGCGCAGGCGGAAAATATTTTCACCCATGAGCAGTTGCTGCGCTATTTCCCTTATTACCTGCTGGT
TAACTCCACTTTTGCTGTGACCGCTGCGCTGGGGGCTGCCGGGCTGGACAGCGAATCGAATCTGATGGCTCGTGTACGAG
CATCGCTGGCTGAAGTGCGTGATCAGGTGACTCATAAAACCTGTCTCAACTACGTGCTGGAAAGTCCGTACTGGAACGTA
AAAGGTAACTTTTTCTGTTATCTGAACGATCATAACGAGAACACCATTGTTGACCCTTCGGTGATCTATTTCGATTTCGC
TAACCCGCTGCAGGCTCAGGAGGTCTGA

Protein sequence :
MIMRIIIDIIVIILLCGSCLTMTLPSEKPATDVAAQCFLNALIRETTDWKLTEYPPDELIIPLDEQKSLHFRVAYFSPTQ
HHRFAFPARLVTASGSYPVDFTTLSRLIIDKLRHQLFLPVPLCETFHQRVLESHAHTQQTIDARHDWTALREKALNFGEA
EQALLTGHAFHPAPKSHEPFNRREAERYLPDMAPHFPLRWFSVDKTQIAGESLHLNLQQRLTRFAAENAPQLLNELSDNQ
WLFPLHPWQGEYLLQQGWCQALVAKGLIKDLGEAGTSWLPTTSSRSLYCATSRDMIKFSLSVRLTNSIRTLSVKEVKRGM
RLARLAQTDGWQMLQVRFPTFRVMQEDGWAGLLDLNGNIMQESLFALRENLLVDQPKSQTNVLVSLTQAAPDGGDSLLVS
AVKRLSDRLGITVQQAAHAWVDAYCQQVLKPLFTAEADYGLVLLAHQQNILVQMLGDLPVGFIYRDCQGSAFMPHATDWL
DSIGEAQAENIFTHEQLLRYFPYYLLVNSTFAVTAALGAAGLDSESNLMARVRASLAEVRDQVTHKTCLNYVLESPYWNV
KGNFFCYLNDHNENTIVDPSVIYFDFANPLQAQEV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
iucA NP_839223.1 siderophore biosynthesis protein Virulence SHI-2 Protein 0.0 99
iucA NP_709454.2 siderophore biosynthesis protein Virulence SHI-2 Protein 0.0 99
iucA AAD44746.1 IucA Virulence SHI-2 Protein 0.0 99
iucA YP_002414046.1 aerobactin siderophore biosynthesis protein Virulence Not named Protein 0.0 99
iucA AAK71631.1 IucA Virulence SHI-3 Protein 0.0 94

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
iucA YP_002405520.1 aerobactin siderophore biosynthesis protein VFG0615 Protein 0.0 99
iucA YP_002405520.1 aerobactin siderophore biosynthesis protein VFG0940 Protein 0.0 99
iucA YP_002405520.1 aerobactin siderophore biosynthesis protein VFG1081 Protein 0.0 94