Gene Information

Name : iucD (EC55989_4642)
Accession : YP_002405517.1
Strain : Escherichia coli 55989
Genome accession: NC_011748
Putative virulence/resistance : Virulence
Product : L-lysine 6-monooxygenase (Lysine N(6)-hydroxylase)
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG3486
EC number : 1.14.13.59
Position : 4757327 - 4758664 bp
Length : 1338 bp
Strand : -
Note : Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3275632, 10064136; Product type e : enzyme

DNA sequence :
ATGAAAAAAAGTGTCGATTTTATTGGTGTCGGGACAGGGCCATTTAATCTCAGCATTGCTGCATTGTCACATCAGATCGA
AGAACTGAACTGTCTCTTCTTTGACGAACATCCTCATTTTTCCTGGCATCCGGGTATGCTGGTACCGGATTGTCATATGC
AGACCGTCTTTCTGAAAGATCTGGTCAGTGCAGTTGCACCTACAAATCCCTACAGCTTTGTTAACTATCTGGTGAAGCAC
AAAAAGTTCTATCGCTTCCTTACAAGCAGGCTACGTACAGTATCCCGTGAAGAGTTTTCTGACTATCTCCGCTGGGCTGC
TGAAGATATGAATAACCTGTATTTCAGTCATACCGTTGAAAATATTGATTTCGACAAAAAAAGTCGATTGTTTCTGGTTC
AGACCAGTCGGGGAGAATATTTTGCCCGCAATATCTGCCTTGGTACAGGAAAACAACCTTATTTACCACCCTGTGTGAAG
CATGTGACACAATCCTGTTTCCATGCCAGTGAAATGAATCTTCGTCGGCCGGACCTGAGTGGAAAACGGATAACCGTGGT
TGGTGGAGGACAGAGTGGTGCAGACCTGTTCCTTAATGCATTACGCGGGGAATGGGGAGAAGCGGCGGAAATAAACTGGG
TCTCACGGCGTAATAATTTTAACGCACTGGATGAGGCTGCTTTTGCTGATGAGTATTTTACACCTGAATATATTTCAGGC
TTCTCCGGACTGAAGGAAGATATTCGCCATCAGTTACTGGATGAGCAGAAAATGACATCGGATGGCATCACTGCCGATTC
TTTACTGACCATTTATCGTGAGTTGTACCACCGTTTTGAAGTTCTGAGAAAACCAAGAAATATCCGTCTGCTACCCAGTC
GCTCGGTAACAACTCTGGAAAGTAGTGGTCCGGGCTGGAGGTTATTGATGGAACATCATCTGGATCAGGGCAGAGAGAGC
CTGGAAAGTGATGTGGTGATTTTCGCCACAGGTTACCGTTCTGCATTGCCACAAATACTTCCCTCACTGATGCCCTTGAT
CACCATGCACGATAAGAACACCTTTAAAGTGCGTGATGACTTCACTCTGGAATGGAGTGGCCCGAAAGAAAATAACATCT
TTGCGGTCAACGCCAGCATGCAAACTCATGGCATCGCCGAACCCCAGCTCAGCCTGATGGCCTGGCGATCTGCACGTATT
CTTAATCGCGTACTGGGGCGTGATTTATTCGATCTCAGTATGCCGCCCGCACTGATTCAGTGGCGCAGCGGCAGCCGGAA
AAAACCGCAGCCGGAGGCTGCTTCTTTAACTCACTATACAGCAAATATTCAGGAATAA

Protein sequence :
MKKSVDFIGVGTGPFNLSIAALSHQIEELNCLFFDEHPHFSWHPGMLVPDCHMQTVFLKDLVSAVAPTNPYSFVNYLVKH
KKFYRFLTSRLRTVSREEFSDYLRWAAEDMNNLYFSHTVENIDFDKKSRLFLVQTSRGEYFARNICLGTGKQPYLPPCVK
HVTQSCFHASEMNLRRPDLSGKRITVVGGGQSGADLFLNALRGEWGEAAEINWVSRRNNFNALDEAAFADEYFTPEYISG
FSGLKEDIRHQLLDEQKMTSDGITADSLLTIYRELYHRFEVLRKPRNIRLLPSRSVTTLESSGPGWRLLMEHHLDQGRES
LESDVVIFATGYRSALPQILPSLMPLITMHDKNTFKVRDDFTLEWSGPKENNIFAVNASMQTHGIAEPQLSLMAWRSARI
LNRVLGRDLFDLSMPPALIQWRSGSRKKPQPEAASLTHYTANIQE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
iucD AAK71634.1 IucD Virulence SHI-3 Protein 0.0 99
iucD AAD44749.1 IucD Virulence SHI-2 Protein 0.0 99
iucD YP_002414043.1 L-lysine 6-monooxygenase Virulence Not named Protein 0.0 99
iucD NP_839220.1 lysine:N6-hydroxylase Virulence SHI-2 Protein 0.0 99
iucD NP_709457.1 lysine:N6-hydroxylase Virulence SHI-2 Protein 0.0 99

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
iucD YP_002405517.1 L-lysine 6-monooxygenase (Lysine N(6)-hydroxylase) VFG0618 Protein 0.0 99
iucD YP_002405517.1 L-lysine 6-monooxygenase (Lysine N(6)-hydroxylase) VFG0937 Protein 0.0 99
iucD YP_002405517.1 L-lysine 6-monooxygenase (Lysine N(6)-hydroxylase) VFG1084 Protein 0.0 99