Gene Information

Name : lpfC (EC55989_4000)
Accession : YP_002404928.1
Strain : Escherichia coli 55989
Genome accession: NC_011748
Putative virulence/resistance : Virulence
Product : Outer membrane usher protein lpfC precursor
Function : -
COG functional category : N : Cell motility
COG ID : COG3188
EC number : -
Position : 4078609 - 4081140 bp
Length : 2532 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 14977923; Product type m : membrane component

DNA sequence :
ATGCATTGGATGCATTTACCTCTCTATCACTACAGAGCGCATTTTTCCTTCTCTCTGCTGGCATTAACGATTGCCAGCTC
GTTACCTGCGTATGGCGGAAAATTTAACCCTAAATTTCTCGAAAACGTTCAGGGTATCGATCAACACATCGACTTGTCGG
TATACGACTCACCTGTCGGCCAGCAAATCCCCGGTAAATACCGGGTTTCGGTGTTTGTAAACGAAGAAAAAATGGCTTCC
CGGACGCTGGATTTTAGTACCGCCAGCGAAGCGAAACGCAAAGCCAGCGGTGAGTCGCTTATGCCTTGCCTTAGCCGGGT
GCAACTGGAAGAAATGGGCGTGCGCGTTGACAGCTTTCCGGCGCTGAAGATGTCACCACCAGAAGCCTGCGTAGCGTTTG
ATGAAATCATTCCCCAGGCCACCAGCCGCTTTGATTTTAATACTCAGACGCTGCATCTTTCCTTTCCACAGGCGGCAATG
ATGATGACCGCTCGCGGCACGGTTGATCCTTCTCGCTGGGACGAAGGAATACCTGCGCTGTTGCTGGATTACAGCTTTAG
TGGCAGCAATGGACGCAATGAAGGTACAGGTTCATCTTCAGATTCGACCAGTGACAGTTATTACCTGAACCTGCGCAGCG
GTTTGAACGTTGGTCCGTGGCGTTTACGTAATAACAGTATCTGGAACCGTACCGATGGCAAAAACCAATGGGATAACGTT
GGTACATCGTTAAACCGGGCAATTATTCCACTTAAATCACAGATAACTCTGGGTGATACCGCCACGCCTGGCGAGATTTT
TGATAGCGTACAAATGCGTGGGGCGTTACTGGCATCCGACGATGAAATGTTGCCGGACAGCCAGCGTGGCTTTGCTCCGG
TAGTGCGCGGCATCGCCAAAAGCAACGCTGAAGTGAGTATCGAACAGAACGGCTATGTCATTTATCGCACTTTTGTTCAG
CCGGGTGCATTTGAGATTAACGATCTCTACGCAACCTCCGGCAGCGGCGACCTGACGGTGATCATTAAAGAAGCCGACGG
AAGTGAACAACGTTTTATCCAGCCGTTTTCGGCGGTGGCGATTTTCCAGCGTGAAGGGTATCTGAAATACAGTCTGGCTG
CCGGTGAATATCGTGCTGGTAATTACGACAGCGATAAACCACATTTCGGGCAGTTTACCGCCATGTACGGCTTGCCGTGG
GGTATGACCGCCTACGGTGGTGCATTGTTGTCGGCAGATTACAGCGCTTTAGCTCTGGGCCTGGGGAAAAACTTCGGTAC
CATTGGCGCAGTATCGGTGGATGTCACTCAGGCGAAAAGTCAGTTACGCAACAATGAAAAAGAGGAAGGCCAGTCTTATC
GCTTCCTCTATTCGAAAAGTTTTGAGGGTGGCACTGACCTGCGTCTGTTGGGCTACAAATACTCAACCAGCGGCTACTAC
ACCTTCCAGGAAGCAACTGATGTTCGCAGTGACGCCGACAGTGATTACCGCCGTTATCACAAGCGCAGCCAGATACAGGG
CAATATTACCCAGCAACTGGGAGACTACGGCTCGGTTTATTTCAATATGACGCAGCAGGATTACTGGAACGTTGACGGTA
AGGAAAACTCCTTAAGCGCCGGTTATCACGGTCACATTGGTCGGGTGAATTACAGCGTGGCCTATACCTGGACGAGAAGT
CCGGAATGGGAAGAAGACGATCGCTTGTGGTCATTCAGTGTTTCCATCCCTCTGGGGGGCGCGTGGAGCAGTTATCGCAT
GACTACCGACCAGAATGGCAAGACGTCGCAACAGGCCTCTGTTAGCGGCACGTTACTGGAAGATCGTAACCTGAGCTATA
ACGTTCAGCAGGGTTACACCAGTAATGGCGTAGGCTACAGTGGCAGCGTCAACATGGGGTATATGGGTGGCTCTGGTAAC
ATTGACGTAGGCTATAACTATTCTAAAGATAACCAACAGGTTAACTATGGCGTGCGCGGCGGTGTCATCGTTCACAGTGA
AGGTATAACGCTTTCGCAGCCTTTAGGCGAAAGTCTGGCGATTGTTTCTGCACCGGGCGCGCGTGGTGGACATGTGGTTA
ACAGCAGCGGCGTAGAAGTTGACTGGATGGGCAACGCCGTGGTGCCTTATCTCACACCATATCGTGAAACCATTGTGGAA
TTGCGTAGCGACACGTTGGGGCAAAACGTTGAACTACAGGAAGCGTTCCAGAAAGTCGTGCCTACTCGTGGTGCAGTTGT
GCGTTCCCGCTTTGATACCCGCGTCGGTTACCGTGTGCTGATGAGCTTAAAACAGGCGAATGGCAACGCAGTACCGTTTG
GTGCAACCGCAGCGTTAATTGATGAGAGCAAACCTGCCAGCAGCATTGTGGGTGAAGAAGGACAGCTTTATATCAGCGGG
ATGCCAGAAGAGGGCGAATTGCAGGTGAGCTGGGGGAACGAGCAGGCGCAACGTTGCCGTGTGCCATTCCGCTTGCCAGA
GAACAAGGACAATGCGGCTATCGTGATGGTTAATGCGGTATGCGAGAAATAA

Protein sequence :
MHWMHLPLYHYRAHFSFSLLALTIASSLPAYGGKFNPKFLENVQGIDQHIDLSVYDSPVGQQIPGKYRVSVFVNEEKMAS
RTLDFSTASEAKRKASGESLMPCLSRVQLEEMGVRVDSFPALKMSPPEACVAFDEIIPQATSRFDFNTQTLHLSFPQAAM
MMTARGTVDPSRWDEGIPALLLDYSFSGSNGRNEGTGSSSDSTSDSYYLNLRSGLNVGPWRLRNNSIWNRTDGKNQWDNV
GTSLNRAIIPLKSQITLGDTATPGEIFDSVQMRGALLASDDEMLPDSQRGFAPVVRGIAKSNAEVSIEQNGYVIYRTFVQ
PGAFEINDLYATSGSGDLTVIIKEADGSEQRFIQPFSAVAIFQREGYLKYSLAAGEYRAGNYDSDKPHFGQFTAMYGLPW
GMTAYGGALLSADYSALALGLGKNFGTIGAVSVDVTQAKSQLRNNEKEEGQSYRFLYSKSFEGGTDLRLLGYKYSTSGYY
TFQEATDVRSDADSDYRRYHKRSQIQGNITQQLGDYGSVYFNMTQQDYWNVDGKENSLSAGYHGHIGRVNYSVAYTWTRS
PEWEEDDRLWSFSVSIPLGGAWSSYRMTTDQNGKTSQQASVSGTLLEDRNLSYNVQQGYTSNGVGYSGSVNMGYMGGSGN
IDVGYNYSKDNQQVNYGVRGGVIVHSEGITLSQPLGESLAIVSAPGARGGHVVNSSGVEVDWMGNAVVPYLTPYRETIVE
LRSDTLGQNVELQEAFQKVVPTRGAVVRSRFDTRVGYRVLMSLKQANGNAVPFGATAALIDESKPASSIVGEEGQLYISG
MPEEGELQVSWGNEQAQRCRVPFRLPENKDNAAIVMVNAVCEK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
fim2D AFH78429.1 putative fimbrial usher protein Virulence KpGI-5 Protein 2e-156 43
lpfC YP_006098365.1 fimbrial outer membrane usher protein Not tested Tn2411 Protein 2e-134 41
sfaF CAC16953.2 SfaF protein Virulence PAI III 536 Protein 6e-157 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lpfC YP_002404928.1 Outer membrane usher protein lpfC precursor VFG0454 Protein 0.0 74
lpfC YP_002404928.1 Outer membrane usher protein lpfC precursor VFG0876 Protein 2e-161 44
lpfC YP_002404928.1 Outer membrane usher protein lpfC precursor VFG0446 Protein 2e-149 41
lpfC YP_002404928.1 Outer membrane usher protein lpfC precursor VFG1645 Protein 3e-157 41
lpfC YP_002404928.1 Outer membrane usher protein lpfC precursor VFG0912 Protein 6e-157 41