Gene Information

Name : intS (EC55989_2593)
Accession : YP_002403615.1
Strain : Escherichia coli 55989
Genome accession: NC_011748
Putative virulence/resistance : Unknown
Product : prophage CPS-53 integrase; CPS-53 (KpLE1) prophage
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0582
EC number : -
Position : 2665518 - 2666675 bp
Length : 1158 bp
Strand : +
Note : Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme

DNA sequence : 
ATGCTCACCGTTAAGCAGATTGAAGCAGCAAAGCCGAAAGAAAAACCATACCGCCTACTCGATGGTAATGGCCTGTACCT
TTATGTCCCTGTGTCAGGGAAAAAGGTATGGCAGCTTCGCTACAAGATTGACGGTAAGGAGAAAATCCTGACCGTAGGAA
AATATCCGCTAATGACTTTGCAGGAGGCAAGGGATAAAGCATGGACTGCGAGGAAAGACATCTCGGTTGGCATCGATCCG
GTAAAAGCGAAAAAGGCTTCGTCTAACAACAATTCCTTTAGTGCGATTTACAAGGAATGGTACGAGCACAAGAAGCAAGT
CTGGTCAGTAGGCTATGCAACTGAACTTGCAAAAATGTTTGATGACGACATTTTACCTATCATCGGCGGCCTTGAAATTC
AGGATATTGAGCCGATGCAACTGCTGGAAGTAATCCGCAGATTTGAAGATCGCGGTGCAATGGAGCGAGCCAACAAAGCC
CGCAGAAGATGCGGCGAGGTTTTCCGTTACGCTATTGTCACTGGTAGGGCTAAATATAACCCGGCGCCTGACCTTGCTGA
CGCCATGAAGGGATACCGCAAGAAGAACTTCCCGTTTCTTCCTGCAGACCAGATCCCTGCATTCAACAAAGCACTGGCAA
CATTTTCAGGAAGTATCGTATCGCTCATTGCCACCAAGGTTTTACGCTATACAGCCCTCAGAACAAAAGAGCTTCGTTCC
ATGCTATGGAAGAACGTCGATTTTGAAAACAGGATTATCACCATTGACGCCAGTGTGATGAAGGGACGCAAAATTCATGT
GGTCCCGATGTCAGACCAGGTGGTTGAACTTCTCACTACGCTAAGCTCAATCACCAAACCAGTATCAGAGTTTGTTTTTG
CCGGGCGCAACGATAAGAAGAAGCCGATCTGCGAGAACGCGGTGCTGCTTGTGATCAAACAAATCGGCTATGAGGGTCTG
GAAAGCGGTCACGGATTCAGGCATGAATTCAGCACGATTATGAACGAGCACGAATGGCCTGCTGACGCTATTGAAGTGCA
ACTGGCACATGCCAACGGCGGATCTGTGCGCGGGATTTACAACCATGCACAGTATCTCGATAAGCGCAGAGAAATGATGC
AGTGGTGGGCGGACTGGCTTGATGGTTTAATAGTTTAA

Protein sequence : 
MLTVKQIEAAKPKEKPYRLLDGNGLYLYVPVSGKKVWQLRYKIDGKEKILTVGKYPLMTLQEARDKAWTARKDISVGIDP
VKAKKASSNNNSFSAIYKEWYEHKKQVWSVGYATELAKMFDDDILPIIGGLEIQDIEPMQLLEVIRRFEDRGAMERANKA
RRRCGEVFRYAIVTGRAKYNPAPDLADAMKGYRKKNFPFLPADQIPAFNKALATFSGSIVSLIATKVLRYTALRTKELRS
MLWKNVDFENRIITIDASVMKGRKIHVVPMSDQVVELLTTLSSITKPVSEFVFAGRNDKKKPICENAVLLVIKQIGYEGL
ESGHGFRHEFSTIMNEHEWPADAIEVQLAHANGGSVRGIYNHAQYLDKRREMMQWWADWLDGLIV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
intL NP_290239.1 integrase for prophage 933L and the LEE pathogenicity island Not tested LEE Protein 1e-86 49
int ACU09430.1 integrase Not tested LEE Protein 7e-87 49
ECs4534 NP_312561.1 integrase Not tested LEE Protein 1e-86 49
int AAC31482.1 CP4-like integrase Not tested LEE Protein 7e-87 49
int CAC39282.1 integrase Not tested LPA Protein 1e-86 49
aec33 AAW51716.1 Int Not tested AGI-3 Protein 1e-86 49
int AAD54663.1 Sai integrase Not tested SHI-2 Protein 1e-85 49
S4835 NP_839238.1 integrase Not tested SHI-2 Protein 1e-85 49
SF3698 NP_709437.1 integrase Not tested SHI-2 Protein 1e-85 49
ESA_03025 YP_001439090.1 hypothetical protein Not tested Not named Protein 3e-82 48
int AAD44730.1 Int Not tested SHI-2 Protein 3e-85 48
unnamed AFX83955.1 integrase Not tested SE-PAI Protein 4e-78 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
intS YP_002403615.1 prophage CPS-53 integrase; CPS-53 (KpLE1) prophage VFG0783 Protein 4e-87 49
intS YP_002403615.1 prophage CPS-53 integrase; CPS-53 (KpLE1) prophage VFG0598 Protein 6e-86 49