Gene Information

Name : yfcS (EC55989_2581)
Accession : YP_002403603.1
Strain : Escherichia coli 55989
Genome accession: NC_011748
Putative virulence/resistance : Virulence
Product : periplasmic pilus chaperone
Function : -
COG functional category : N : Cell motility
COG ID : COG3121
EC number : -
Position : 2650567 - 2651319 bp
Length : 753 bp
Strand : -
Note : Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor

DNA sequence :
ATGTCTGATTTACTTTGCTCTGCCAAATTGGGTGCTACGACGCTAGCGTTACTGCTTAGCGCTGCCAGTTTGTCTGCCCA
GGCTTCTGTAACGCCAGATCGTACCCGTTTGATATTTAATGAAAGCGACAAATCAATCAGCGTGACGTTGCGCAATAACG
ATCCGAAACTGCCTTATCTGGCCCAAAGCTGGATCGAAGATGAAAAGGGTAACAAGATCAGTTCACCGTTAACTGTTCTG
CCACCGGTGCAACGCATCGATTCAATGATGAACGGGCAGGTAAAAGTGCAGGGAATGCCGGATATCAACAAATTGCCTGC
CGATCGTGAAAGCCTGTTCTACTTCAACGTGCGTGAGATCCCGCCAAAATCAAACAAAGCCAACACGCTGCAAATAGCAC
TACAAACGCGTATTAAGTTGTTCTGGCGACCGAAGGCGCTGGAGAACGTCAGCATGAAAAACCCCTGGCAATATAAGGTT
ACTTTAACCCGCAACGGTCAGGAATTTACCGTCAATAACCCGACACCGTATTACGTCATTTTCAGTAATGCCAGCACACA
GAAAAATGGCAATCCGGCAGCCGGTTTCTCGCCAATAGTGATGTCGCCGAAAACCTCTGCACCGCTGAATGTGAAGATGG
GTAGCGTGCCGGTACTGACCTATGTCAACGACTATGGCGCTCGGATGCCGCTCTTTTTCACTTGCAACGGTAACAGTTGC
CAGGTCGATGAAGAGCAGAGCCGCAAAGGCTGA

Protein sequence :
MSDLLCSAKLGATTLALLLSAASLSAQASVTPDRTRLIFNESDKSISVTLRNNDPKLPYLAQSWIEDEKGNKISSPLTVL
PPVQRIDSMMNGQVKVQGMPDINKLPADRESLFYFNVREIPPKSNKANTLQIALQTRIKLFWRPKALENVSMKNPWQYKV
TLTRNGQEFTVNNPTPYYVIFSNASTQKNGNPAAGFSPIVMSPKTSAPLNVKMGSVPVLTYVNDYGARMPLFFTCNGNSC
QVDEEQSRKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
prfD CAD42028.1 PrfD protein Virulence PAI II 536 Protein 1e-47 45
papD AAL67413.1 PapD Virulence PAI II CFT073 Protein 3e-47 45
papD AAZ04423.1 P pilus chaperone Virulence PAI I APEC-O1 Protein 3e-47 45
papD_2 NP_757033.1 PapD protein Virulence PAI II CFT073 Protein 4e-47 45
papD YP_002414014.1 Chaperone protein PapD Not tested Not named Protein 4e-47 45
papD YP_854253.1 pilus assembly protein chaperone PapD Virulence PAI I APEC-O1 Protein 4e-47 45
papD NP_755464.1 PapD protein Virulence PAI I CFT073 Protein 1e-42 44
pixD CAE85158.1 PixD protein Not tested PAI V 536 Protein 2e-47 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
yfcS YP_002403603.1 periplasmic pilus chaperone VFG1547 Protein 7e-48 45
yfcS YP_002403603.1 periplasmic pilus chaperone VFG0896 Protein 2e-47 45
yfcS YP_002403603.1 periplasmic pilus chaperone VFG0885 Protein 6e-43 44