Gene Information

Name : irp (EC55989_2205)
Accession : YP_002403251.1
Strain : Escherichia coli 55989
Genome accession: NC_011748
Putative virulence/resistance : Virulence
Product : permease and ATP-binding protein of yersiniabactin-iron ABC transporter YbtP
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG1132
EC number : -
Position : 2238888 - 2240690 bp
Length : 1803 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10231486, 11320115; Product type t : transporter

DNA sequence :
ATGTCATCTCAATCATCCAGTACTGAATCGCTGTCCCGATTTCCTCTCTGGCAGGTGATTACACCGGTTCGCAGGAAGGT
TATTTTAGCTATGGCGCTGGCGGGGCTGGCGGCATTAACCAGCCTGGGGGCGCTCCTTTTTCTGGCGTGGAGCCTGCGTG
ACATTCGCGCGACGCCTGACGCTATTCCGGCCTGGCCGCTGGGCGGCGTGATCGGCTGCGTGGTCTTAACTTTTGTTCTG
CGCTTACAGGCGTTCAACACCTCTCATTACGCGGCTTTTCATCTGGAGAACATTCTGCGCAGCAGGTTAGCCCGTAAAGC
ATTGCAGCTTCCGCCTGGCGTGTTACAGCAAATGGGCTGCGGGTCAGTGGCGAAAGTGATGCTGGATGACGTGAAGTCGT
TACATATTTTTGTGGCCGACAGCACGCCGCTCTATGCCCGCGCGATCATCATGCCGCTGGCGACAATCGTTATCTTGTTC
TGGCTGGACTGGCGGCTGGCAATCGCGACGCTGGGGGTACTGGCGTTTGGATCGGTTATTCTCGTGCTCGCCCGCCAGCG
TTCGGAAAATATGGCTCAGCGTTATCATAAGGCGCGCGAGCAGGTTAGCGCGGCGGTTATTGAGTTCGTGCAGGCCATGC
CCGTGGTGAGAACGTTTGATAGCGGCAGCACCAGTTTTTTGCGCTATCAACGCGCCCTTGAAGAGTGGGTCGATGTGCTC
AAAACCTGGTATCGCAAAGCCGGTTTTTCAGCGCGTTTTTCCTTCTCGATTCTGAATCCTCTCCCGACCCTGTTTGTCCT
GATCTGGTCGGGATACGGCCTGTTGCACTATGGCAGTTTCGATTTTATCGCGTGGGTGGCCGTTTTACTGCTGGGCAGCG
GAATGGCCGAAGCCGTAATGCCAATGATGATGCTCAATAACCTGGTCGCGCAAACGCGTTTAAGCATTCAGCGTATTTAT
CAGGTTCTCGCGATGCCGGAGTTATCGCTGCCGCAGTCTGACCAGCAGCCGCAAGAGGCGAGCATTACCTTTGAGCAGGT
GAGCTTTCATTATCCGCAAGCGCGTACTGGCGCCGCGTTGCAGGAGGTGAGCTTTCATGTGCCTGCCGGGCAAATTGTGG
CGCTGGTCGGGCCAAGCGGCGCCGGAAAAAGCACCGTGGCGCGCTTGCTGCTGCGTTACGCCGACCCGGACAAAGGCCAT
ATCCGTATTGGCGGCGTGGATCTGCGTGATATGCAGACGGACACCCTGATGAAGCAACTCTCGTTTGTGTTTCAGGACAA
CTTCCTTTTTGCCGACACGATAGCCAATAACATTCGTCTGGGCGCGCCGGATACGCCGCTGGAGGCGGTTATAGCGGCGG
CCAGAGTGGCGCAGGCCCATGATTTTATTAGCGCTCTGCCAGAAGGTTACAACACTCGAGTCGGGGAACGTGGGGTATTT
CTCTCCGGCGGCCAGCGGCAGCGCATTACTATCGCCCGGGCGCTTTTGCAGGATCGCCCCATCCTGGTGCTCGATGAGGC
GACGGCGTTTGCTGACCCGGAAAACGAAGCGGCGCTTATCAAGGCGCTCGCGGCGGCCATGCGTGGCCGGACGGTCATCA
TGGTCGCGCATCGTCTCTCAATGGTGACTCAGGCCGATGTGATATTGCTGTTTTCCGACGGACAGCTCAGGGAAATGGGG
AACCATACGCAACTGTTGGCGCAGGGCGGCCTGTATCAACGGCTCTGGCAACACTATCAGCAGGCGCAGCATTGGGTGCC
GGGTGGAACACAGGAAGAGGTGGTGGAAAATGAAAGACAATAA

Protein sequence :
MSSQSSSTESLSRFPLWQVITPVRRKVILAMALAGLAALTSLGALLFLAWSLRDIRATPDAIPAWPLGGVIGCVVLTFVL
RLQAFNTSHYAAFHLENILRSRLARKALQLPPGVLQQMGCGSVAKVMLDDVKSLHIFVADSTPLYARAIIMPLATIVILF
WLDWRLAIATLGVLAFGSVILVLARQRSENMAQRYHKAREQVSAAVIEFVQAMPVVRTFDSGSTSFLRYQRALEEWVDVL
KTWYRKAGFSARFSFSILNPLPTLFVLIWSGYGLLHYGSFDFIAWVAVLLLGSGMAEAVMPMMMLNNLVAQTRLSIQRIY
QVLAMPELSLPQSDQQPQEASITFEQVSFHYPQARTGAALQEVSFHVPAGQIVALVGPSGAGKSTVARLLLRYADPDKGH
IRIGGVDLRDMQTDTLMKQLSFVFQDNFLFADTIANNIRLGAPDTPLEAVIAAARVAQAHDFISALPEGYNTRVGERGVF
LSGGQRQRITIARALLQDRPILVLDEATAFADPENEAALIKALAAAMRGRTVIMVAHRLSMVTQADVILLFSDGQLREMG
NHTQLLAQGGLYQRLWQHYQQAQHWVPGGTQEEVVENERQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtP NP_669704.1 permease and ATP-binding protein of yersiniabactin-iron ABC transporter Virulence HPI Protein 0.0 99
ybtP NP_993009.1 permease and ATP-binding protein of yersiniabactin-iron ABC transporter Virulence HPI Protein 0.0 99
ybtP YP_853073.1 inner membrane ABC-transporter Not tested PAI IV APEC-O1 Protein 0.0 99
irp6 YP_001006813.1 lipoprotein inner membrane ABC-transporter Not tested HPI Protein 0.0 99
ybtP YP_070126.1 lipoprotein inner membrane ABC-transporter Virulence HPI Protein 0.0 99
irp6 YP_002346904.1 lipoprotein inner membrane ABC transporter Not tested HPI Protein 0.0 99
ybtP CAA21388.1 - Virulence HPI Protein 0.0 99
irp6 CAB46573.1 lipoprotein inner membrane ABC-transporter, Irp6 Virulence HPI Protein 0.0 98

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
irp YP_002403251.1 permease and ATP-binding protein of yersiniabactin-iron ABC transporter YbtP BAC0432 Protein 0.0 99