Gene Information

Name : irp (EC55989_2203)
Accession : YP_002403249.1
Strain : Escherichia coli 55989
Genome accession: NC_011748
Putative virulence/resistance : Virulence
Product : yersiniabactin-iron transporter permease YbtX
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG2814
EC number : -
Position : 2235826 - 2237229 bp
Length : 1404 bp
Strand : -
Note : Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter

DNA sequence :
TTGAGCAGGGTACTCATGCGCAATTGCTCTCACATCATGGACGTTATCAGGCGCTGTGGCAGGCGCAAATGGCCGCGCGC
GTGTGGCGCGACGACGGGGTTTCCGCGTCTGGAGAGTGGGTGCATGAGTGATGTTCAGTCGAATGTGAAACCGCTGACGT
TGACGACCGGGCGGGTGATTTTTGCTATTGCCGGCGTCTATGTGACGCAGAGTCTGGTATCGGCGCTGTCTATGCAGTCC
TTACCCGCGCTGGTGCGCGCTGCTGGCGGTTCGCTGGCGCTTGCCGGTGCGACAACCCTGTTTATGCTGCCCTGGGCGCT
GAAGTTTATTTGGGCGTCGTGGATCGAGCGCTGGCGGCTTCCGCCCGGTAGCCAGGAACGCCGTTCCCGCATGTTAATCC
TGCGTGGTCAGGTCGCGCTAGCGGCGATCCTGACTATTGTCGCAGCGATTGGCTGGTTTGGGCGAGAAGGGGGATTCCCC
GATACGCAAATCGTCGCGTTATTTGTTCTGTTTATGGTGGCAGGCACGGTCGCCTCCACCATTGATATCGCCAGCGACGG
CTTTTGTGTCGATCAACTGACCCGCACGGGTTACGGCTGGGGAAACAGCGTGCAGGTCGGCGGCAGCTATCTGGGAATGA
TGTGCGGCGGCGGGGTGTTCCTGATGCTGTCGGCGGCATCCGGCTGGCCTGTCGCCATGCTGATGATGGCGGTGCTGATT
ATGGCGCTGTCACTCCCGCTGTGGCGCATTACGGAGCCGACGCGAACAGCGACTATCCCGCATGTTCCGGCGTTAGGTTA
TGCGCTAAGGAGGAAGCAGGCTCGCCTGGGCTTACTGCTGGTATTGATGCTGAATTCAGGCATGCGGTTTGTGCTGCCTC
TTCTGGCACCGCTGTTGTTGGATCATGGGTTGAGCATGTCCGCATTGGGCGCGCTGTTCAGCGGCGGCAATATTGCAGCG
GGCATAGCAGGAACGCTGGCCGGCGGATTGCTGATGAAATACACCTCACCCGGCAGAGCGCTGTTGACGGCTTATGGCGT
CCAGGGGATCGCGCTGCTGGCGGTGGTGATGACTCTCATGATGGCGCCGGGTCATCTGCTGCTGCAGATTCTCCAGTGTC
TGGTCCTTGTCCAGTCCATTTCGCTGGCCTGCGCGCTGGTCTGTCTTTACGCCACGCTGATGTCGCTTTCATCGCCTTTG
CAGGCCGGTGTCGACTTCACCCTCTTTCAATGTACTGATGCGGCAATCGCCATTCTGGCAGGCGTTATCGGTGGCGTTGT
TGCTCAACATTTTGGCTATGCGGCCTGCTTCCTGTTTGCCGGGGCATTCACGTTGCTGGCGGCGTGGGTTGCTTATATCC
GGCTGCATTCGGCAAGAGAACTGATGACAAGCGCAATTGATTGA

Protein sequence :
MSRVLMRNCSHIMDVIRRCGRRKWPRACGATTGFPRLESGCMSDVQSNVKPLTLTTGRVIFAIAGVYVTQSLVSALSMQS
LPALVRAAGGSLALAGATTLFMLPWALKFIWASWIERWRLPPGSQERRSRMLILRGQVALAAILTIVAAIGWFGREGGFP
DTQIVALFVLFMVAGTVASTIDIASDGFCVDQLTRTGYGWGNSVQVGGSYLGMMCGGGVFLMLSAASGWPVAMLMMAVLI
MALSLPLWRITEPTRTATIPHVPALGYALRRKQARLGLLLVLMLNSGMRFVLPLLAPLLLDHGLSMSALGALFSGGNIAA
GIAGTLAGGLLMKYTSPGRALLTAYGVQGIALLAVVMTLMMAPGHLLLQILQCLVLVQSISLACALVCLYATLMSLSSPL
QAGVDFTLFQCTDAAIAILAGVIGGVVAQHFGYAACFLFAGAFTLLAAWVAYIRLHSARELMTSAID

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp8 YP_002346906.1 signal transducer Not tested HPI Protein 2e-119 99
ybtX YP_070128.1 MFS superfamily transporter signal transducer Virulence HPI Protein 2e-119 99
ybtX YP_853071.1 hypothetical protein Not tested PAI IV APEC-O1 Protein 2e-138 99
ybtX CAA21386.1 - Virulence HPI Protein 3e-139 99
ybtX NP_669702.1 hypothetical protein Virulence HPI Protein 1e-141 99
ybtX NP_993011.1 signal transducer Virulence HPI Protein 1e-141 99
irp8 CAB46571.1 signal transducer, Irp8 Virulence HPI Protein 7e-136 98
irp8 YP_001006811.1 putative signal transducer Not tested HPI Protein 3e-117 98