Gene Information

Name : irp (EC55989_2202)
Accession : YP_002403248.1
Strain : Escherichia coli 55989
Genome accession: NC_011748
Putative virulence/resistance : Virulence
Product : salicylate synthase Irp9
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0147
EC number : -
Position : 2234494 - 2235798 bp
Length : 1305 bp
Strand : -
Note : catalyzes the conversion of chorismate to salicylate in the biosynthesis of the siderophore yersiniabactin

DNA sequence :
ATGAAAATCAGTGAATTTTTACATCTGGCGTTACCAGAGGAACAATGGCTACCGACGATTTCTGGCGTTTTACGCCAGTT
CGCAGAAGAAGAGTGTTATGTCTATGAGCGTCAACCCTGTTGGTATTTAGGCAAAGGGTGCCAGGCACGGCTGCACATTA
ATGCCGACGGAACGCAGGCGACATTTATTGATGATGCCGGGGAGCAAAAATGGGCGGTGGATTCCATTGCCGACTGCGCG
CGTCGTTTTATGGCGCATCCTCAGGTGAAAGGACGTCGGGTATATGGACAGGTTGGGTTCAACTTTGCGGCGCATGCGCG
GGGGATTGCCTTTAACGCCGGGGAGTGGCCGCTGCTGACGTTAACCGTTCCCCGTGAAGAACTTATTTTTGAAAAGGGAA
ATGTCACCGTTTATGCGGACTCCGCCGACGGGTGCCGACGTTTGTGCGAGTGGGTAAAAGAGGCCGGTACAACGACGCAG
AACGCACCACTGGCGGTGGATACCGCCCTCAATGGTGAGGCATATAAACAACAGGTTGCGCGCGCCGTTGCGGAGATCCG
CCGTGGCGAGTATGTCAAAGTGATTGTCTCGCGCGCCATTCCCCTGCCATCGCGGATTGATATGCCCGCCACGCTGTTAT
ACGGGCGGCAGGCAAACACGCCTGTGCGCTCGTTTATGTTCCGTCAGGAAGGACGCGAAGCGCTGGGCTTTAGCCCGGAA
CTGGTGATGTCAGTGACGGGCAATAAAGTGGTCACTGAACCGCTTGCGGGCACCCGCGATCGCATGGGAAACCCGGAGCA
TAATAAGGCGAAAGAGGCAGAACTGCTGCACGACAGTAAAGAGGTGCTTGAGCATATCCTTTCTGTCAAAGAAGCTATTG
CTGAACTGGAGGCTGTTTGCCAGCCGGGCAGCGTGGTGGTTGAAGATTTAATGTCGGTTCGCCAGCGCGGCAGCGTTCAG
CATCTGGGGTCTGGCGTGAGCGGTCAGCTTTCGGAAAACAAGGATGCCTGGGATGCGTTTACCGTGCTGTTTCCGTCGAT
TACCGCCTCAGGTATCCCTAAAAATGCTGCTCTGAACGCGATTATGCAAATTGAGAAGACGCCGCGAGAGCTTTATTCCG
GCGCAATCCTGCTGCTGGACGATACGCGCTTTGATGCGGCGCTAGTTCTGCGTTCCGTATTTCAGGATAGCCAGCGCAGC
TGGATACAGGCGGGGGCGGGAATCATCGCGCAATCTACTCCGGAACGCGAACTGACAGAAACCCGGGAGAAATTAGCGAG
CATTGCGCCCTATTTAATGGTGTAG

Protein sequence :
MKISEFLHLALPEEQWLPTISGVLRQFAEEECYVYERQPCWYLGKGCQARLHINADGTQATFIDDAGEQKWAVDSIADCA
RRFMAHPQVKGRRVYGQVGFNFAAHARGIAFNAGEWPLLTLTVPREELIFEKGNVTVYADSADGCRRLCEWVKEAGTTTQ
NAPLAVDTALNGEAYKQQVARAVAEIRRGEYVKVIVSRAIPLPSRIDMPATLLYGRQANTPVRSFMFRQEGREALGFSPE
LVMSVTGNKVVTEPLAGTRDRMGNPEHNKAKEAELLHDSKEVLEHILSVKEAIAELEAVCQPGSVVVEDLMSVRQRGSVQ
HLGSGVSGQLSENKDAWDAFTVLFPSITASGIPKNAALNAIMQIEKTPRELYSGAILLLDDTRFDAALVLRSVFQDSQRS
WIQAGAGIIAQSTPERELTETREKLASIAPYLMV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
APECO1_1052 YP_853070.1 salicylate synthase Irp9 Not tested PAI IV APEC-O1 Protein 0.0 99
ybtS YP_002346907.1 salicylate synthase Irp9 Not tested HPI Protein 0.0 99
ybtS NP_669701.1 salicylate synthase Irp9 Not tested HPI Protein 0.0 99
ybtS YP_070129.1 salicylate synthase Irp9 Not tested HPI Protein 0.0 99
ybtS CAA21385.1 - Virulence HPI Protein 0.0 99
irp9 CAB46570.1 salicylate synthetase, Irp9 Virulence HPI Protein 0.0 99
irp9 YP_001006810.1 salicylate synthase Irp9 Not tested HPI Protein 0.0 99
ybtS NP_993012.1 salicylate synthase Irp9 Not tested HPI Protein 0.0 99
unnamed AAD17661.1 unknown Not tested HPI Protein 0.0 93